952 research outputs found
Detection and emotional evaluation of an electric vehicle’s exterior sound in a simulated environment
Electric vehicles are quiet at low speeds and thus potentially pose a threat to pedestrians’ safety. Laws are formulating worldwide that mandate these vehicles emit sounds to alert the pedestrians of the vehicles’ approach. It is necessary that these sounds promote a positive perception of the vehicle brand, and understanding their impact on soundscapes is also important. Detection time of the vehicle sounds is an important measure to assess pedestrians’ safety. Emotional evaluation of these sounds influences assessment of the vehicle brand. Laboratory simulation is a new approach for evaluating exterior automotive sounds. This study describes the implementation of laboratory simulation to compare the detection time and emotional evaluation of artificial sounds for an electric vehicle. An Exterior
Sound Simulator simulated audio-visual stimuli of an electric car passing a crossroad of a virtual town at 4.47 ms-1 (10 mph), from the perspective of a pedestrian standing at the crossroad. In this environment, 15 sounds were tested using experiments where participants detected the car and evaluated its sound using perceptual dimensions. Results show that these sounds vary significantly in their detection times and emotional evaluations, but crucially that traditional metrics like dB(A) do not always relate to the detection of these sounds. Detection time and emotional evaluation do not have significant correlation. Hence, sounds of a vehicle could be detected
quickly, but may portray negative perceptions of the vehicle. Simulation provides a means to more fully evaluate potential electric vehicle sounds against the competing criteria
Towards a methodology for assessing electric vehicle exterior sounds
Laws mandate that electric vehicles emit sounds to ensure pedestrians' safety by alerting pedestrians of the vehicles' approach. Additionally, manufacturers want these sounds to promote positive impressions of the vehicle brand. A reliable and valid methodology is needed to evaluate electric vehicles' exterior sounds. To help develop such a methodology, this paper examines automotive exterior sound evaluation methods in the context of experimental design and cognitive psychology. Currently, such evaluations are usually conducted on road or inside a laboratory; however, a virtual environment provides advantages of both these methods but none of their limitations. The stimuli selected for evaluations must satisfy legislative guidelines. Methods for presenting and measuring the stimuli can affect study outcomes. A methodology is proposed for conducting evaluations of an electric vehicle's exterior sounds, testing its detectability and emotional evaluation. An experiment tested the methodology. Thirty-one participants evaluated an electric car in a virtual environment of a town's T-junction with 15 exterior sounds as stimuli. The car's arrival time, direction of approach, and, thus, distance to pedestrian varied across conditions. Detection time of the sound and pleasantness and powerfulness evaluations of the car were recorded. The vehicle's arrival time and approach direction affected its detectability and emotional evaluation; thus, these are important elements to vary and control in studies. Overall, the proposed methodology increases the realistic context and experimental control than in existing listening evaluations. It benefits by combining two competing elements necessary for assessing electric vehicle exterior sounds, namely, pedestrians' safety and impressions of the vehicle brand
FABRICATION OF SILVER NANOPARTICLES SYNTHESIZED FROM GANODERMA LUCIDUM INTO THE COTTON FABRIC AND ITS ANTIMICROBIAL PROPERTY
Objectives: To synthesize and characterize the silver nanoparticles from the mushroom, Ganoderma lucidum and application of this nanoparicle into the cotton fabric to impart sterility.Methods: SNPs synthesised by using the fruiting body of Ganoderma lucidum, Resulted AgNPs fabricated cotton fabric was characterized using SEM (Scanning Electron Microscope) and silver nanoparticles produced from G. lucidum were characterized using UV-VIS Spectrophotometer, SEM, FE-SEM (Field Emission Scanning Electron Microscope), EDAX (Energy dispersion X-RAY spectroscopy)and XRD (X-ray diffraction spectroscpy). Then the incorporated cotton fabric was tested against 5 different strains.Results: The results showed that cotton fabric incorporated with AgNPs displayed significant antibacterial activity against all the selected strains.Conclusion: It was demonstrated that application of biologically synthesized AgNPs production and fabrication of cotton fabric, indicates sterile properties. Further it can be modified as perfect wound dressing material in the health care market. Moreover to avoid the damage to the environment the fabric containing silver nanoparticles can be treated with cyanogenic bacterial strains
The “Fingerprint” of Cancer Extends Beyond Solid Tumor Boundaries: Assessment With a Novel Ultrasound Imaging Approach
Abnormalities of microvascular morphology have been associated with tumor angiogenesis for more than a decade, and are believed to be intimately related to both tumor malignancy and response to treatment. However, the study of these vascular changes in-vivo has been challenged due to the lack of imaging approaches which can assess the microvasculature in 3-D volumes non-invasively. Here, we use contrast-enhanced “acoustic angiography” ultrasound imaging to observe and quantify heterogeneity in vascular morphology around solid tumors
Nevus sebaceous of Jadassohn of face with infundibular and keratinous cyst in an adolescent Arab male-a rare case report
Nevus Sebaceous of Jadassohn is rare hamartomatous skin lesion. We report an interesting case of an Adolescent Arab male 18yr old, who presented to us with a velvety plaque of 7cm length in his left preauricular area. Excision biopsy revealed Nevus sebaceous of Jadassohn with infundibular and keratinous cyst. The lesion is present since birth started as a tiny lesion and grown to the current size. No such large sized lesion on the face has ever been reported in the medical literature till date. We advise an early excision as they have strong potential for malignant change
A survey of risk tolerance to multiple sclerosis therapies
OBJECTIVE: To determine tolerance to various risk scenarios associated with current multiple sclerosis (MS) therapies.
METHODS: People with MS from the North American Research Committee on Multiple Sclerosis Registry\u27s online cohort and the National Multiple Sclerosis Society were invited to complete a questionnaire on tolerance to real-world risks associated with a hypothetical therapy. Multiple risks levels were presented, including skin rash, infection, kidney injury, thyroid injury, liver injury, and progressive multifocal leukoencephalopathy (PML).
RESULTS: Both PML and kidney injury had the lowest risk tolerance (RT) at 1:1,000,000, and thyroid and infection risks had the highest tolerance at 1:1,000. Men, younger individuals, and participants with greater disability reported a higher tolerance to all risk scenarios. Those who were currently taking an MS therapy reported higher tolerance than those not taking any therapy. Participants taking infusion therapies reported high tolerance to all risks, and those taking injectables reported a lower tolerance.
CONCLUSION: People with MS displayed a wide range of RT for MS therapies. Our study identified sex, age, disability, and current disease-modifying therapy use to be associated with RT
Obstructive sleep apnea and electrocardiographic P-wave morphology.
INTRODUCTION: Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder with important cardiovascular implications. Left atrial abnormality can be identified by electrocardiographic P-wave morphology and is considered an important risk for atrial fibrillation (AF) and stroke, both of which have been associated with OSA. We hypothesized that severity of OSA would be associated with more abnormal electrocardiographic P-wave morphology as indicated by P-wave terminal force in V
METHODS: Patients who underwent clinically indicated polysomnography and had 12-lead ECG were identified through medical record review. Logistic regression was used to determine the associations between the measures of OSA severity (apnea hypopnea index [AHI] and mean nocturnal oxygen [O
RESULTS: A total of 261 patients (mean age: 57 years old, male: 52%) were included in the study. Multivariate analysis showed that AHI was associated with abnormal PTFV
CONCLUSION: In a sleep clinic cohort, there was significant association between OSA severity and ECG-defined left atrial abnormality
Spatial analysis of individual- and village-level sociodemographic characteristics associated with age at marriage among married adolescents in rural Niger.
BACKGROUND: Niger has the highest prevalence of child marriage in the world. While child marriage in Niger is clearly normative in the sense that it is commonly practiced, the social and contextual factors that contribute to it are still unclear. METHODS: Here, we tested the importance of village-level factors as predictors of young age at marriage for a group of married adolescent girls (N = 1031) in the Dosso district of rural Niger, using multi-level and geographic analyses. We aggregated significant individual level factors to determine whether, independent of a girl's own sociodemographic characteristics, the impact of each factor is associated at the village level. Finally, we tested for spatial dependence and heterogeneity in examining whether the village-level associations we find with age at marriage differ geographically. RESULTS: The mean age of marriage for girls in our study was 14.20 years (SD 1.8). Our statistical results are consistent with other literature suggesting that education is associated with delayed marriage, even among adolescent girls. Younger ages at marriage are also associated with a greater age difference between spouses and with a greater likelihood of women being engaged in agricultural work. Consistent with results at the individual level, at the village level we found that the proportion of girls who do agricultural work and the mean age difference between spouses were both predictive of a lower age at marriage for individual girls. Finally, mapping age at marriage at the village level revealed that there is geographical variation in age at marriage, with a cluster of hot spots in the Hausa-dominated eastern area where age at marriage is particularly low and a cluster of cold spots in the Zarma-dominated western areas where age at marriage is relatively high. CONCLUSIONS: Our findings suggest that large-scale approaches to eliminating child marriage in these communities may be less successful if they do not take into consideration geographically and socially determined contextual factors at the village level
A study to assess the level of knowledge regarding prevention and management of acute respiratory infection among mothers of children 0-5 years in selected hospital in Siliguri
Background: In developing countries like India acute respiratory infection (ARI) contributes in child mortality upto 75% and out of 10, 7 deaths are due to ARI. The knowledge of the mothers towards the disease is a significant determinant of child’s health.Methods: A descriptive cross-sectional study included 100 mothers of children 0-5 years admitted in pediatric ward and postnatal ward in selected hospital Siliguri during the year 2022 in the month of March. Data was collected using structured interview method.Results: 20% of mothers have good knowledge in prevention and 33% had good knowledge in management of ARI.Conclusions: As the leading cause of death among children, knowledge assessment about ARI among the mothers is very important, which helps for better understanding of the intensity of the problem
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