Knowledge of Maternal and Newborn Care Among Primary Level Health Workers in Kapilvastu District of Nepal

Background: Higher maternal and neonatal deaths are common in low‑ and middle‑income countries; due to less access to skilled help. Adequate knowledge and skills on maternal and newborn care (MNC) of community health workers can improve maternal and newborn health.Aims: To identify the knowledge of primary level health workers on some components of MNC.Subjects and Methods: Respondents were selected using simple random sampling method. For collecting the data, enumerators visited health institutions for 2 months from 1|st October to 31st November 2012, and structured interview schedule was used to gather the information. A cross‑sectional study was conducted in a total of one hundred and thirty‑seven primary level health workers in Kapilvastu district, Nepal. The Chi‑square test was employed to examine the association between the knowledge of health workers on MNC and designation and work experience. Data were analyzed using SPSS version 17.Results: In a total of 137 primary level health workers, more than half 53.2% (73/137) were senior auxiliary health workers/health assistant. Health workers having correct knowledge on contents of MNC were‑registration 32.1% (44/137), major components of antenatal care 57.7% (79/137), danger signs of pregnancy 39.4% (54/137), five cleans 59.1% (81/137), postnatal health problems 54.0% (74/137), majority to health action to newborn care, newborn bath and meaning of exclusive breastfeeding. There was a statistical association between designation of health workers and above‑mentioned components of MNC (P < 0.05).Conclusions: The differentials in the knowledge of MNC among primary level health suggest improving knowledge of the grass root level health workers with appropriate training and development programs.Keywords: Knowledge, Maternal and newborn care, Primary level health worker

Enhanced Removal Efficiency of Arsenic and Copper from Aqueous Solution Using Activated Acorus calamus Based Adsorbent

Water security, due to heavy metal pollution in water resources, has become a serious problem in modern urbanized society. Plants with a good source of cellulose, hemicellulose, pectin, lignin, etc., are the most promising adsorbents for the removal of heavy metals from water. In this work, for the first time, a low-cost local plant named Acorus calamus (AC; flag root or sweet flag) and citric acid modified AC root powder (CAMAC) were used as potential adsorbents. The samples were characterized by SEM, FT-IR, XRD, and the sorption properties were investigated by different parameters, such as solution pH, batch kinetic study, batch isotherm, effect of adsorbent dose, effect of initial concentration, and effect of contact time. The results of ACRP on removal efficiency of copper (II) and arsenic (III) in an aqueous solution showed an excellent adsorption behavior (~ 80 % adsorption efficiency). This study opens up an easy and economical method for the decontamination of harsh polluting metal ions from water. This work is licensed under a Creative Commons Attribution 4.0 International License

{TADA}: {T}axonomy Adaptive Domain Adaptation

Traditional domain adaptation addresses the task of adapting a model to a novel target domain under limited or no additional supervision. While tackling the input domain gap, the standard domain adaptation settings assume no domain change in the output space. In semantic prediction tasks, different datasets are often labeled according to different semantic taxonomies. In many real-world settings, the target domain task requires a different taxonomy than the one imposed by the source domain. We therefore introduce the more general taxonomy adaptive domain adaptation (TADA) problem, allowing for inconsistent taxonomies between the two domains. We further propose an approach that jointly addresses the image-level and label-level domain adaptation. On the label-level, we employ a bilateral mixed sampling strategy to augment the target domain, and a relabelling method to unify and align the label spaces. We address the image-level domain gap by proposing an uncertainty-rectified contrastive learning method, leading to more domain-invariant and class discriminative features. We extensively evaluate the effectiveness of our framework under different TADA settings: open taxonomy, coarse-to-fine taxonomy, and partially-overlapping taxonomy. Our framework outperforms previous state-of-the-art by a large margin, while capable of adapting to target taxonomies

Effect of Heat Stress on Crossbred Dairy Cattle in Tropical Nepal: Impact on Blood Parameters

Chitwan district of Nepal has been known as the dairy kingdom of the country considering its strategic location andpotential to easily provision inputs and produce as well as market quality milk across the country. However, theclimate especially during summer has been a challenge to farmers that potentially compromise the daily milk yieldof cows. Therefore, sixteen crossbred dairy cattle were placed in a RCBD fashion to assess the impacts of cold waterbathing in ameliorating effect of heat stress on their performance and body physiology. Routine assessment of themicroclimate within the experimental shed and blood parameters was made. The results from the experimentinferred that frequency of bathing (none, once, twice or thrice a day) did not have any significant impact onHaemoglobin, Haematocrit, Sodium, Potassium, Chloride and Bicarbonate levels in the blood plasma(p>0.05). Inaddition, the animals did not exhibit any signs of physiological distress clinically either. A detailed study scopingtemperature humidity index and over a number of other milk and blood parameters are to be tested across a numberof other available breeds too in order for the researchers to come to a meaningful strategy to beat the heat stress

Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity

To the Editor, So far, little attention has been paid to the link between immunosenescence and the dramatic mortality rate of coronavirus disease 2019 (COVID-19) in older age groups. Indeed, the number of cases of COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is very low among children and teenagers, in contrast to the increased frequency in adults and the elderly, who are also more at risk of developing very serious symptoms and death (Guan et al. 2020; Wu and McGoogan 2020). As shown in Fig. 1, a similar epidemiological profile was observed during previous coronavirus (severe acute respiratory syndrome coronavirus 1, SARS-CoV-1, and Middle east respiratory syndrome coronavirus, MERS-CoV) outbreaks (Jia et al. 2009; Salamatbakhsh et al. 2019). Notably, the same trend was also noted during West Nile virus and, with some exceptions in very young children, Ebolavirus outbreaks (Bower et al. 2016; Hayes et al. 2005). Likely this phenomenon is multifactorial. For instance, in elderly individuals with severe COVID-19, associated comorbidities are much more prevalent (Guan et al. 2020). In addition, the progressive accumulation of senescent cells during life may play a role in the vulnerability of old people to COVID-19, resulting in reduced functionality of the organs, such as the lungs, and facilitating conditions for the development of fibrosis. Moreover, senescent cells can generate a pro-inflammatory environment, referred to as SASP (for senescence-associated secretory phenotype), which includes many inflammatory cytokines (e.g., interleukin-6) and contributes to the basal hyperinflammatory status characteristic of the old person. This hyperinflammatory status might influence the expression of ACE2, CD147, cyclophilins, CD26, and other CoV-associated molecules in human tissues, thus favoring viral entry (Radzikowska et al. 2020). It likely also constitutes an already unbalanced pro-inflammatory background, on which the development of an exacerbated inflammatory response and acute respiratory distress syndrome may be facilitated upon SARS-CoV-2 infection

A Pilot Survey of an M Dwarf Flare Star with Swift's UV Grism

The near-ultraviolet (NUV) spectral region is a useful diagnostic for stellar flare physics and assessing the energy environment of young exoplanets, especially as relates to prebiotic chemistry. We conducted a pilot NUV spectroscopic flare survey of the young M dwarf AU Mic with the Neil Gehrels Swift Observatory's UltraViolet and Optical Telescope. We detected four flares and three other epochs of significantly elevated count rates during the 9.6 hours of total exposure time, consistent with a NUV flare rate of $\sim$0.5 hour$^{-1}$. The largest flare we observed released a minimum energy of 6$\times$10$^{33}$ erg between 1730-5000 \r{A}. All flares had durations longer than the $\sim$14-17 minute duration of each Swift visit, making measuring total flare energy and duration infeasible.Comment: Published in Research Notes of the AAS (RNAAS

A study to Assess the Knowledge Regarding Human Right of Mentally Ill Patient among Community People in Kaski, Pokhara,Nepal

Introduction: Mental health problems raise many human rights issues. People with mental illness are exposed to human rights violation within and outside the health care context. Because of lack of awareness, people with mental illness and their families do not exercise their rights. Psychiatric patients are most vulnerable groups in community. Incidence of violation of rights of mentally ill patients can be avoided if the community people become aware of them. Objective: To assess knowledge regarding human rights and myth of mental illness among community people. Method: A descriptive crosssectional study was conducted among 140 community people of Ritthepani-27, Kaski, Nepal. Non probability convenient sampling technique was adopted to collect the data. Inclusion criteria included head of the family of the selected community who were willing to participate in the study. Data was collected through face to face interview using a structured questionnaire. Results: In the present study, it was found that 46.40% of the community people had inadequate knowledge regarding human rights of mentally ill patients. There was no significant association between demographic variables and knowledge score of the respondents. The study found that more than half of the respondents (51%) had belief that mental illness is not related to physical health. Likewise 36.4% believed mental illness is caused by supernatural power and evil and 30% believed that marriage can cure mental illness. Conclusion: Based on findings, it is concluded that the level of knowledge regarding rights of mentally ill patient is inadequate and there is a high prevalence of myths and misconceptions related to mental illness among the adult population. So, there is need to conduct awareness raising activities in the community