559 research outputs found
Study of the performance of a large scale water-Cherenkov detector (MEMPHYS)
MEMPHYS (MEgaton Mass PHYSics) is a proposed large-scale water Cherenkov
experiment to be performed deep underground. It is dedicated to nucleon decay
searches, neutrinos from supernovae, solar and atmospheric neutrinos, as well
as neutrinos from a future Super-Beam or Beta-Beam to measure the CP violating
phase in the leptonic sector and the mass hierarchy. A full simulation of the
detector has been performed to evaluate its performance for beam physics. The
results are given in terms of "Migration Matrices" of reconstructed versus true
neutrino energy, taking into account all the experimental effects.Comment: Updated after JCAP's referee's comment
Future large-scale water-Cherenkov detector
MEMPHYS (MEgaton Mass PHYSics) is a proposed large-scale water-Cherenkov
experiment to be performed deep underground. It is dedicated to nucleon decay
searches and the detection of neutrinos from supernovae, solar, and atmospheric
neutrinos, as well as neutrinos from a future beam to measure the CP violating
phase in the leptonic sector and the mass hierarchy. This paper provides an
overview of the latest studies on the expected performance of MEMPHYS in view
of detailed estimates of its physics reach, mainly concerning neutrino beams
Exocytotic exposure and recycling of membrane antigens of chromaffin granules: ultrastructural evaluation after immunolabeling.
MEMPHYS:A large scale water Cerenkov detector at Fr\'ejus
A water \v{C}erenkov detector project, of megaton scale, to be installed in
the Fr\'ejus underground site and dedicated to nucleon decay, neutrinos from
supernovae, solar and atmospheric neutrinos, as well as neutrinos from a
super-beam and/or a beta-beam coming from CERN, is presented and compared with
competitor projects in Japan and in the USA. The performances of the European
project are discussed, including the possibility to measure the mixing angle
and the CP-violating phase .Comment: 1+33 pages, 14 figures, Expression of Interest of MEMPHYS projec
Establishing a nu_{mu,tau} Component in the Solar Neutrino Flux
We point out that the recoil electron kinetic energy spectra in the nu-e
elastic scattering are different for incident nu_{e} or nu_{mu,tau}, and hence
one can in principle establish the existence of the nu_{mu,tau} component in
the solar neutrino flux by fitting the shape of the spectrum. This would be a
new model-independent test of the solar neutrino oscillation in a single
experiment, free from astrophysical and nuclear physics uncertainties. For the
^7Be neutrinos, it is possible to determine the nu_{mu,tau} component at
BOREXINO or KamLAND, if the background is sufficiently low. Note that this
effect is different from the distortion in the incident neutrino energy
spectrum, which has been discussed in the literature.Comment: 12 pages, 3 figures, uses psfig. Figures reorganized, one corrected,
conclusions unchange
Progress on a spherical TPC for low energy neutrino detection
The new concept of the spherical TPC aims at relatively large target masses
with low threshold and background, keeping an extremely simple and robust
operation. Such a device would open the way to detect the neutrino-nucleus
interaction, which, although a standard process, remains undetected due to the
low energy of the neutrino-induced nuclear recoils. The progress in the
development of the fist 1 m prototype at Saclay is presented. Other physics
goals of such a device could include supernova detection, low energy neutrino
oscillations and study of non-standard properties of the neutrino, among
others.Comment: 3 pages, talk given at the 9th Workshop on Topics in Astroparticle
and Underground Physics, Zaragoza, September 10-1
Eigenvector Expansion and Petermann Factor for Ohmically Damped Oscillators
Correlation functions in ohmically damped
systems such as coupled harmonic oscillators or optical resonators can be
expressed as a single sum over modes (which are not power-orthogonal), with
each term multiplied by the Petermann factor (PF) , leading to "excess
noise" when . It is shown that is common rather than
exceptional, that can be large even for weak damping, and that the PF
appears in other processes as well: for example, a time-independent
perturbation \sim\ep leads to a frequency shift \sim \ep C_j. The
coalescence of () eigenvectors gives rise to a critical point, which
exhibits "giant excess noise" (). At critical points, the
divergent parts of contributions to cancel, while time-independent
perturbations lead to non-analytic shifts \sim \ep^{1/J}.Comment: REVTeX4, 14 pages, 4 figures. v2: final, 20 single-col. pages, 2
figures. Streamlined with emphasis on physics over formalism; rewrote Section
V E so that it refers to time-dependent (instead of non-equilibrium) effect
An internal deletion in the cytoplasmic tail reverses the apical localization of human NGF receptor in transfected MDCK cells.
An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ
Background: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are present. We describe a live kidney slice model in which pericyte-mediated vasa recta constriction/dilation can be visualized in situ. Methods: Confocal microscopy was used to image calcein, propidium iodide and Hoechst labelling in âliveâ kidney slices, to determine tubular and vascular cell viability and morphology. DIC video-imaging of live kidney slices was employed to investigate pericyte-mediated real-time changes in vasa recta diameter. Results: Pericytes were identified on vasa recta and their morphology and density were characterized in the medulla. Pericyte-mediated changes in vasa recta diameter (10â30%) were evoked in response to bath application of vasoactive agents (norepinephrine, endothelin-1, angiotensin-II and prostaglandin E2) or by manipulating endogenous vasoactive signalling pathways (using tyramine, L-NAME, a cyclo-oxygenase (COX-1) inhibitor indomethacin, and ATP release). Conclusions: The live kidney slice model is a valid complementary technique for investigating vasa recta function in situ and the role of pericytes as regulators of vasa recta diameter. This technique may also be useful in exploring the role of tubulovascular crosstalk in regulation of medullary blood flow
The LAGUNA design study- towards giant liquid based underground detectors for neutrino physics and astrophysics and proton decay searches
The feasibility of a next generation neutrino observatory in Europe is being
considered within the LAGUNA design study. To accommodate giant neutrino
detectors and shield them from cosmic rays, a new very large underground
infrastructure is required. Seven potential candidate sites in different parts
of Europe and at several distances from CERN are being studied: Boulby (UK),
Canfranc (Spain), Fr\'ejus (France/Italy), Pyh\"asalmi (Finland),
Polkowice-Sieroszowice (Poland), Slanic (Romania) and Umbria (Italy). The
design study aims at the comprehensive and coordinated technical assessment of
each site, at a coherent cost estimation, and at a prioritization of the sites
within the summer 2010.Comment: 5 pages, contribution to the Workshop "European Strategy for Future
Neutrino Physics", CERN, Oct. 200
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