Deregulation of conveyancing markets in England and Wales

There has been much concern in recent years with whether the ‘privilege’ of self- regulation accorded to the professions works for or against the public interest (Federal Trade Commission, 1984; Monopolies and Mergers Commission, 1970, 1976a and 1976b; Department of Trade and Industry, 1989; Courts and Legal Services Act, 1990). Ogus (1993) argues that ‘Self-regulation has had a bad press’ and that ‘most of this criticism is well-founded in relation to some forms of self- regulation’. Economists have been, traditionally, highly critical of many aspects of professional self-regulation.2 More recently, there has been a greater awareness of the informational asymmetry inherent in professional markets which demands some protection for the (infrequent) consumer of personal professional services (see, for example, Dingwall and Fenn (1987)). Commentators have identified three principal instruments of such selfregulators which work against the public interest: (1) restrictions on entry; (2) restrictions on fee competition; and (3) restrictions on advertising and other means of promoting a competitive process within the profession.

Habitat and bycatch effects on population parameters of inshore lizardfish (Synodus foetens) in the north central Gulf of Mexico

We examined the effect of habitat and shrimp trawl bycatch on the density, size, growth, and mortality of inshore lizardfish (Synodus foetens), a nonexploited species that is among the most widespread and abundant benthic fishes in the north central Gulf of Mexico. Results of quarterly trawl sampling conducted from spring 2004 through spring 2005 revealed that inshore lizardfish are most abundant on sand habitat, but larger fish are more common on shell rubble habitat. There was no significant difference in fish density between habitats exposed to shrimp trawling on the open shelf versus those habitats within a permitted artificial reef zone that served as a de facto no-trawl area; this finding indicates that either inshore lizardfish experienced minimal effects from trawling or, more likely, that fish moved between trawled and nontrawled habitats. Exploitation ratio (bycatch mortality/total morality) estimates derived from catch curve analysis ranged from 0.43 inside the artificial reef zone to 0.55 outside the reef zone, thus indicating that inshore lizardfish are subject to significant fishing mortality in the north central Gulf of Mexico despite the lack of a directed fishery for the species. We infer from this result that effects of shrimp trawl bycatch may be significant at the population level for nonexploited species and that a broader ecosystem-scale examination of bycatch effects is warranted

Otolith Microchemical Fingerprints of Age-0 Red Snapper, Lutjanus campechanus, from the Northern Gulf of Mexico

Red snapper, Lutjanus campechanus, in the northern Gulf of Mexico (Gulf) are believed to constitute a single stock. However, tagging and genetics studies suggest there is little mixing between populations of red snapper in the northern Gulf, and little is known about mixing rates of adult fish. The long-term goal of our work is to determine if age-0 red snapper from different nursery areas have unique microchemical fingerprints in their sagittal otoliths, and if so, can the microchemical fingerprints at the core of adult otoliths be used to determine retrospectively nursery area of origin. Ultimately, we hope to use the microchemical fingerprints at the core of adult snapper otoliths to estimate adults\u27 mixing rates and movement patterns. In this study, the objective was to determine if age-0 red snapper collected from different northern Gulf nursery areas in summer and fall 1995 did contain unique microchemical fingerprints. Sagittal otoliths of age-0 red snapper collected off the coasts of Alabama/Mississippi, Louisiana, and Texas were analyzed using inductively coupled plasma atomic emission spectrometry (ICP-AES). Twelve elements in the sagittae of age-0 snapper were analyzed with ICP-AES. Of these, eight were put into a stepwise discriminant function analysis with the best-fitted model including Mg, Se, As, Fe, and AI, entered in that order (MANOVA, P \u3c 0.001). Cross-validated classification accuracies were 92% for Texas fish, 91% for Louisiana fish, and 92% for Alabama/Mississippi fish. Therefore, it appears that otolith microchemistry can be used to infer nursery area of age-0 red snapper. Future work will focus on (1) establishing the temporal stability of age-0 red snapper otolith microchemical fingerprints and (2) inclusion of analyses of age-structured samples from adult red snapper otolith cores to estimate their nursery area of origin and mixing rates

Hypercube matrix computation task

A major objective of the Hypercube Matrix Computation effort at the Jet Propulsion Laboratory (JPL) is to investigate the applicability of a parallel computing architecture to the solution of large-scale electromagnetic scattering problems. Three scattering analysis codes are being implemented and assessed on a JPL/California Institute of Technology (Caltech) Mark 3 Hypercube. The codes, which utilize different underlying algorithms, give a means of evaluating the general applicability of this parallel architecture. The three analysis codes being implemented are a frequency domain method of moments code, a time domain finite difference code, and a frequency domain finite elements code. These analysis capabilities are being integrated into an electromagnetics interactive analysis workstation which can serve as a design tool for the construction of antennas and other radiating or scattering structures. The first two years of work on the Hypercube Matrix Computation effort is summarized. It includes both new developments and results as well as work previously reported in the Hypercube Matrix Computation Task: Final Report for 1986 to 1987 (JPL Publication 87-18)

Movement of Red Snapper, Lutjanus campechanus, in the North Central Gulf of Mexico: Potential Effects of Hurricanes

Site fidelity and movement of red snapper, Lutjanus campechanus, were estimated from a tagging study conducted off the coast of Alabama from March 1995 to January 1997. Red snapper were caught using rod and reel over nine artificial reef sites, with three reefs each located at 21-m, 27-m, and 32-m depths. During the study, 1,604 fish were tagged, and 174 recaptures were made of 167 individuals. On 4 October 1995, the eye of Hurricane Opal passed within 40 km of the artificial reef sites. When recaptures were stratified according to whether or not they were at liberty during Opal, storm effect was the most significant factor in predicting the likelihood of movement and magnitude of movement by tagged red snapper. Eighty percent of recaptured red snapper that were not at liberty during Opal were recaptured at their site of release. Fish that were at liberty during Opal, however, had a significantly higher likelihood of movement away from their site of release (P \u3c 0.001). These fish also moved significantly further than those that were not at liberty during Opal (P \u3c 0.001). Fish that were at liberty during Opal moved a mean distance (± SE) of 32.6 km (± 6.81), compared to a mean distance (± SE) of 2.5 km (± 1.10) for fish that were tagged and recaptured before Opal, and a mean distance (± SE) of 1.7 km (± 0.43) for fish that were tagged and recaptured after Opal. Heretofore, it has generally been accepted that adult red snapper demonstrate strong site fidelity and genetic homogeneity in the stock was hypothesized to result from larval drift or due to historic mixing on longer time scales. This study documents movement of adult red snapper on spatial scales that would facilitate stock mixing and implicates large-scale climatic events, such as hurricanes, as important factors in stock mixing dynamics

Application of Otolith Chemical Signatures to Estimate Population Connectivity of Red Snapper In the Western Gulf of Mexico

Otolith chemical signatures of Red Snapper Lutjanus campechanus from six nursery regions were used to estimate the sources of recruits to four sampling regions in the western Gulf of Mexico (Gulf) and to estimate whether postsettlement mixing of Red Snapper occurs between the U.S. and Mexican portions of the western Gulf. In a previous study, region-specific otolith signatures (element : Ca ratios: Ba:Ca, Mg:Ca, Mn:Ca, Sr:Ca, and Li:Ca; stable isotope delta values: δ13C and δ18O) were developed based on age-0 Red Snapper (2005–2007 year-classes) sampled from the six nursery areas. In the present study, subadult and adult Red Snapper (ages 1–3) belonging to those same year-classes were collected from four sampling regions within the western Gulf (two regions in U.S. waters; two regions along the Mexican continental shelf) during summer in 2006–2008. Left sagittal otoliths were used to age subadults and adults to the corresponding nursery year-classes, and right sagittal otoliths were cored for chemical analysis. Off the southwestern U.S. coast, the sampled age-1–3 Red Snapper included locally derived recruits as well as recruits from the northwestern Gulf nursery region. However, analytical results were inconclusive with respect to estimating the connectivity between Red Snapper populations in U.S. and Mexican waters of the western Gulf

Polarized QPOs from the INTEGRAL polar IGRJ14536-5522 (=Swift J1453.4-5524)

We report optical spectroscopy and high speed photometry and polarimetry of the INTEGRAL source IGRJ14536-5522 (=Swift J1453.4-5524). The photometry, polarimetry and spectroscopy are modulated on an orbital period of 3.1564(1) hours. Orbital circularly polarized modulations are seen from 0 to -18 per cent, unambiguously identifying IGRJ14536-5522 as a polar. Some of the high speed photometric data show modulations that are consistent with quasi-periodic oscillations (QPOs) on the order of 5-6 minutes. Furthermore, for the first time, we detect the (5-6) minute QPOs in the circular polarimetry. We discuss the possible origins of these QPOs. We also include details of HIPPO, a new high-speed photo-polarimeter used for some of our observations.Comment: Accepted for publication by MNRAS. The paper contains 7 figures and 1 tabl

Scheduling a project to maximize its net present value: An integer programming approach

We describe an integer programming algorithm for determining scheduled start and finish times for the activities of a project subject to resource limitations during each period of the schedule duration. The objective is to maximize the net present value of the project to the firm. A depth-first branch and bound solution procedure searches over the feasible set of finish or completion times for each of the activities of the project. Fathoming criteria based upon the concept of a network cut originally developed to solve the duration minimization version of this problem are extended in this paper to solve the net present value problem. These fathoming decision rules prevent many potentially inferior solutions from being explicitly evaluated. Computational experience reported demonstrates the efficacy of the approach.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/31003/1/0000678.pd

Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis

<p>Abstract</p> <p>Background</p> <p>Melanoma vaccines have not been optimized. Adjuvants are added to activate dendritic cells (DCs) and to induce a favourable immunologic milieu, however, little is known about their cellular and molecular effects in human skin. We hypothesized that a vaccine in incomplete Freund's adjuvant (IFA) would increase dermal Th1 and Tc1-lymphocytes and mature DCs, but that repeated vaccination may increase regulatory cells.</p> <p>Methods</p> <p>During and after 6 weekly immunizations with a multipeptide vaccine, immunization sites were biopsied at weeks 0, 1, 3, 7, or 12. In 36 participants, we enumerated DCs and lymphocyte subsets by immunohistochemistry and characterized their location within skin compartments.</p> <p>Results</p> <p>Mature DCs aggregated with lymphocytes around superficial vessels, however, immature DCs were randomly distributed. Over time, there was no change in mature DCs. Increases in T and B-cells were noted. Th2 cells outnumbered Th1 lymphocytes after 1 vaccine 6.6:1. Eosinophils and FoxP3⁺cells accumulated, especially after 3 vaccinations, the former cell population most abundantly in deeper layers.</p> <p>Conclusions</p> <p>A multipeptide/IFA vaccine may induce a Th2-dominant microenvironment, which is reversed with repeat vaccination. However, repeat vaccination may increase FoxP3⁺T-cells and eosinophils. These data suggest multiple opportunities to optimize vaccine regimens and potential endpoints for monitoring the effects of new adjuvants.</p> <p>Trail Registration</p> <p>ClinicalTrials.gov Identifier: NCT00705640</p