In vitro studies of antistress and antiallergic effects of semecarpus anacardium fruit in asthma

Semicarpus anacardium Linn. (Anacardiaceae) is a deciduous moderate sized tree. The plant is commonly known as Ballataka (Sanskrit), Bhela (Hindi) and marking nut in English. Fruits are acrid and sweet and used traditionally in the treatment of asthma. Allergy and stress are important contributing factors in asthma; hence, our objective was to study the effect of plant extracts on milk-induced leucocytosis (antistress) and milk-induced eosinophilia (antiallergic) as no work is done in this direction and to check a possible antiasthmatic role of the plant. Extracts were given at the dose of 50 and 100 mg/kg, p.o., to mice. Ethyl acetate and ethanol extracts showed significant decrease in leukocytes and eosinophils count. These results confirm the use of S. anacardium fruits as antistress and antiallergic agents in the treatment asthma.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Synthesis and evaluation of some new substituted phenylthiazole derivatives and their antitubercular activity

1033-1037A new series of substituted phenylthiazole derivatives have been synthesized and the structures of these compounds have been established on the basis of spectral and elemental analysis. All compounds have been screened for antitubercular activity by Middle brook 7H9 agar medium against H37Rv. strain. Most of these compounds have shown promising antitubercular activity

Robust TCP (TCP-R) with Explicit Packet Drop Notification (EPDN) for Satellite Networks

Abstract. Numerous studies have shown that packet reordering is com-mon, especially in satellite networks where there are regular handoffs oc-curring between neighboring satellites. Reordering of packets decreases the TCP performance of a network, mainly because it leads to overesti-mation of the congestion of the network. We consider satellite networks and analyze the performance of such networks when reordering of packets occurs. We propose a solution that could significantly improve the perfor-mance of the network when reordering of packets occurs in the satellite network. We report results of our simulation experiments, which support this claim. Our solution is based on enabling the senders to distinguish between dropped packets and reordered packets.

Synthesis and microbiological evaluation of 2-acetanilido-4-arylthiazole derivatives

1929-1932A series of compounds have been synthesized by reacting 2-amino 4-arylthiazole with different substituted acetanilides and chloroacetylation of 2-amino 4-arylthiazole or their substituted derivatives. Ten different substituted compounds synthesized out of the 2-acetanilido 4-arylthiazole derivatives and 2-pyrazine 4-arylthiazole have been evaluated for the antifungal and antibacterial activities. These compounds have showed moderate antibacterial and very good activity

Synthesis of <i>N</i>-3(4-(4-chlorophenyl thiazole-2-yl)-(2-(amino)methyl)-quinazoline-4(3<i style="">H</i>)-one and their derivatives for antitubercular activity

1778-1781A new series of N-3[4-(4-chlorophenyl thiazole-2-yl)-2-amino methyl] quinazoline-4(3H)-one and their derivatives are synthesized. The structures of the title compounds are confirmed on the basis of IR and 1H NMR. The compounds are screened for their antitubercular activity, using H37Rv strain on L J medium. All the compounds have showed moderate to promising antitubercular activity

Synthesis and evaluation of some novel 1,3,4-thiadiazoles for antidiabetic activity

615-618A new series of 1,3,4-thiadiazole derivatives are synthesized and the structures of these compounds have been established on the basis of spectral and elemental analysis. All the compounds are evaluated for antidiabetic activity on albino rats. Most of these compounds show promising antidiabetic activity

Phaeoacremonium krajdenii, a Cause of White Grain Eumycetoma

We describe the first case of white grain pedal eumycetoma caused by Phaeoacremonium krajdenii in a 41-year-old man from Goa, India. Based on histological examination of biopsy tissue showing serpentine granules, a culture of the granules yielding phaeoid fungal colonies, and morphological characteristics and sequence comparison of the partial β-tubulin gene with the ex-type isolate of P. krajdenii, the causal agent was identified as P. krajdenii

Synthesis and antidiabetic activity of 2-amino [5'(4-sulphonylbenzylidine)-2,4-thiazolidinedione]-7-chloro-6-fluorobenzothiazole

2404-2408A new series of 2-amino[5'(4-sulphonylbenzylidine)-2,4-thiazolidinedione]-7-chloro-6-fluorobenzothiazole were synthe­sized. The structures of the compounds were confirmed by UV-Vis, IR and NMR spectroscopy. The title compounds were screened for their antidiabetic activity on albino rats

Synthesis and Evaluation of Some 1,4-Dihydropyridine and Their Derivatives as Antihypertensive Agents.

698-701A series of 1, 4-dihydro-2, 6-dimethyl-4-{4-[3-(2-aminopyrazine/1-amino-4-methyl piperazine)-2-hydroxy propoxy]-phenyl}-pyridine-3, 5-carbamoyl have been synthesized and the structure of the compounds have been confirmed by IR, ¹H NMR , MS & elemental analysis. The title compounds have been evaluated for antihypertensive activity by tail-cuff method. Some of these compounds have been found to exhibit excellent antihypertensive activity