335 research outputs found
Very hard states in neutron star low-mass X-ray binaries
We report on unusually very hard spectral states in three confirmed
neutron-star low-mass X-ray binaries (1RXS J180408.9-342058, EXO 1745-248, and
IGR J18245-2452) at a luminosity between ~ 10^{36-37} erg s^{-1}. When fitting
the Swift X-ray spectra (0.5 - 10 keV) in those states with an absorbed
power-law model, we found photon indices of \Gamma ~ 1, significantly lower
than the \Gamma = 1.5 - 2.0 typically seen when such systems are in their so
called hard state. For individual sources very hard spectra were already
previously identified but here we show for the first time that likely our
sources were in a distinct spectral state (i.e., different from the hard state)
when they exhibited such very hard spectra. It is unclear how such very hard
spectra can be formed; if the emission mechanism is similar to that operating
in their hard states (i.e., up-scattering of soft photons due to hot electrons)
then the electrons should have higher temperatures or a higher optical depth in
the very hard state compared to those observed in the hard state. By using our
obtained \Gamma as a tracer for the spectral evolution with luminosity, we have
compared our results with those obtained by Wijnands et al. (2015). We confirm
their general results in that also our sample of sources follow the same track
as the other neutron star systems, although we do not find that the accreting
millisecond pulsars are systematically harder than the non-pulsating systems.Comment: Accepted for publication in MNRA
Enhancing the Sustainability of the Aviation Industry: Airlinesâ Commitment to âGreenâ Practices
The aviation industry represents an important polluter, being responsible for increasing
environmental impacts on global scale. Aiming to approach the adoption of suitable policies
in the aviation industry towards the achievement of the national and international
sustainability goals, the present research tackles airlinesâ commitment to aviation-related
environmental issues, as well as their willingness to adopt sustainable aviation fuel (i.e., bio
jet fuel) and sustainable development strategies, focusing on those companies operating
flights in the Karol WojtyĆa Airport (Bari, Italy). The paper adopts the Ï2 test and the logistic
regression to investigate three different hypotheses related to airlinesâ headquarters, carriersâ
typology (i.e., low-cost or not, flag carriers or not) and years of service. Results outline that
traditional airlines, either flag carriers or not, as well as South and North American
companies, are more likely to be aware of aviation environmental consequences, publishing
environmental reports and offering to passengers the chance to participate to climate change
reduction (e.g., through online carbon offset programs or more expensive ticket to produce
bio jet fuels). In addition, airlines transiting in Karol WojtyĆa Airport show a small
willingness to share information through environmental reports and are scarcely intentioned
to make use of bio jet fuels, confirming that low-cost companies are still less attentive
towards aviation environmental issues. The present research contributes to the empirical
studies on sustainable aviation and carriersâ commitment to environmental strategies,
highlighting the need to enhance carbon offsets programs and digital technologies as the
online compensation of CO2 emissions
Do Patients with Bronchiectasis Have an Increased Risk of Developing Lung Cancer? A Systematic Review
Background: Initial evidence supports the hypothesis that patients with non-cystic fibrosis bronchiectasis (NCFB) have a higher risk of lung cancer. We systematically reviewed the available literature to define the characteristics of lung malignancies in patients with bronchiectasis and the characteristics of patients who develop bronchiectasis-associated lung cancer. Method: This study was performed based on the PRISMA guidelines. The review protocol was registered in PROSPERO. Results: The frequency rates of lung cancer in patients with NCFB ranged from 0.93% to 8.0%. The incidence rate was 3.96. Cancer more frequently occurred in the elderly and males. Three studies found an overall higher risk of developing lung cancer in the NCFB population compared to the non-bronchiectasis one, and adenocarcinoma was the most frequently reported histological type. The effect of the co-existence of NCFB and COPD was unclear. Conclusions: NCFB is associated with a higher risk of developing lung cancer than individuals without NCFB. This risk is higher for males, the elderly, and smokers, whereas concomitant COPDâs effect is unclear
Endoscopic Technologies for Peripheral Pulmonary Lesions: From Diagnosis to Therapy
Peripheral pulmonary lesions (PPLs) are frequent incidental findings in subjects when performing chest radiographs or chest computed tomography (CT) scans. When a PPL is identified, it is necessary to proceed with a risk stratification based on the patient profile and the characteristics found on chest CT. In order to proceed with a diagnostic procedure, the first-line examination is often a bronchoscopy with tissue sampling. Many guidance technologies have recently been developed to facilitate PPLs sampling. Through bronchoscopy, it is currently possible to ascertain the PPLâs benign or malignant nature, delaying the therapyâs second phase with radical, supportive, or palliative intent. In this review, we describe all the new tools available: from the innovation of bronchoscopic instrumentation (e.g., ultrathin bronchoscopy and robotic bronchoscopy) to the advances in navigation technology (e.g., radial-probe endobronchial ultrasound, virtual navigation, electromagnetic navigation, shape-sensing navigation, cone-beam computed tomography). In addition, we summarize all the PPLs ablation techniques currently under experimentation. Interventional pulmonology may be a discipline aiming at adopting increasingly innovative and disruptive technologies
The very faint X-ray binary IGR J17062-6143: a truncated disc, no pulsations, and a possible outflow
We present a comprehensive X-ray study of the neutron star low-mass X-ray binary IGR J17062-6143, which has been accreting at low luminosities since its discovery in 2006. Analysing NuSTAR, XMMâNewton, and Swift observations, we investigate the very faint nature of this source through three approaches: modelling the relativistic reflection spectrum to constrain the accretion geometry, performing high-resolution X-ray spectroscopy to search for an outflow, and searching for the recently reported millisecond X-ray pulsations. We find a strongly truncated accretion disc at
77+22â18
gravitational radii (âŒ164âkm) assuming a high inclination, although a low inclination and a disc extending to the neutron star cannot be excluded. The high-resolution spectroscopy reveals evidence for oxygen-rich circumbinary material, possibly resulting from a blueshifted, collisionally ionized outflow. Finally, we do not detect any pulsations. We discuss these results in the broader context of possible explanations for the persistent faint nature of weakly accreting neutron stars. The results are consistent with both an ultra-compact binary orbit and a magnetically truncated accretion flow, although both cannot be unambiguously inferred. We also discuss the nature of the donor star and conclude that it is likely a CO or OâNeâMg white dwarf, consistent with recent multiwavelength modelling
Somatic BRCA Mutation in a Cholangiocarcinoma Patient for HBOC Syndrome Detection
BRCA-associated hereditary breast and ovarian cancer syndrome (HBOC) is characterized by an increased risk of developing other malignancies including cholangiocarcinoma (CCA). Somatic BRCA mutations have been reported in CCA, but they have yet to be utilized in a proband case to identify HBOC in families. Two healthy daughters of a deceased female patient who had had metachronous breast cancer and CCA received genetic counseling to assess their cancer risk. Somatic BRCA1/2 mutation analysis was performed by next-generation sequencing on the DNA extracted from a formalin-fixed, paraffin-embedded CCA biopsy specimen of their mother. A pathogenic variant was identified (c.6468_6469delTC in a BRCA2 gene mutation). Germline BRCA mutation analysis of the two daughters detected the same pathogenic variant in one of them. For the first time, a CCA somatic BRCA mutation has been used to identify a family with HBOC
Short-term cardiac outcome in survivors of COVID-19: a systematic study after hospital discharge
Background: COVID-19 has caused considerable morbidity and mortality worldwide and cardiac involvement has been reported during infection. The short-term cardiac outcome in survivors of COVID-19 is not known. Objective: To examine the heart of patients who survived COVID-19 and to compare the cardiac outcome between patients who recovered from mild-to-moderate or severe illness. Methods: With use of ECG and echocardiography, we examined the heart of 105 patients who had been hospitalized with COVID-19 and were consecutively recruited after hospital discharge while attending follow-up visits. Survivors of COVID-19 were compared with 105 matched controls. We also compared the cardiac outcome and lung ultrasound scan between COVID-19 patients who had mild-to-moderate or severe illness. Results: Cardiac data were collected a median of 41\ua0days from the first detection of COVID-19. Symptoms were present in a low percentage of patients. In comparison with matched controls, no considerable structural or functional differences were observed in the heart of survivors of COVID-19. Lung ultrasound scan detected significantly greater residual pulmonary involvement in COVID-19 patients who had recovered from severe than mild-to-moderate illness. No significant differences were detected in ECG tracings nor were found in the left and right ventricular function of patients who had recovered from mild-to-moderate or severe illness. Conclusions: In a short-term follow-up, no abnormalities were identified in the heart of survivors of COVID-19, nor cardiac differences were detected between patients who had different severity of illness. With the limitations of a cross-sectional study, these findings suggest that patients who recover from COVID-19 do not have considerable cardiac sequelae. Graphic abstract: [Figure not available: see fulltext.
Accreting Millisecond X-Ray Pulsars
Accreting Millisecond X-Ray Pulsars (AMXPs) are astrophysical laboratories
without parallel in the study of extreme physics. In this chapter we review the
past fifteen years of discoveries in the field. We summarize the observations
of the fifteen known AMXPs, with a particular emphasis on the multi-wavelength
observations that have been carried out since the discovery of the first AMXP
in 1998. We review accretion torque theory, the pulse formation process, and
how AMXP observations have changed our view on the interaction of plasma and
magnetic fields in strong gravity. We also explain how the AMXPs have deepened
our understanding of the thermonuclear burst process, in particular the
phenomenon of burst oscillations. We conclude with a discussion of the open
problems that remain to be addressed in the future.Comment: Review to appear in "Timing neutron stars: pulsations, oscillations
and explosions", T. Belloni, M. Mendez, C.M. Zhang Eds., ASSL, Springer;
[revision with literature updated, several typos removed, 1 new AMXP added
Design and Analysis of the Cis-Lunar Navigation for the ArgoMoon CubeSat Mission
In the framework of the Artemis-1 mission, 10 CubeSats will be released, including the 6U CubeSat ArgoMoon, built by the Italian company Argotec and coordinated by the Italian Space Agency. The primary goal of ArgoMoon is to capture images of the Interim Cryogenic Propulsion Stage. Then, ArgoMoon will be placed into a highly elliptical orbit around the Earth with several encounters with the Moon. In this phase, the navigation process will require a precise Orbit Determination (OD) and a Flight Path Control (FPC) to satisfy the navigation requirements. The OD will estimate the spacecraft trajectory using ground-based radiometric observables. The FPC is based on an optimal control strategy designed to reduce the dispersion with respect to the reference trajectory and minimize the total ÎV. A linear approach was used to determine the optimal targets and the number and location of the orbital maneuvers. A covariance analysis was performed to assess the expected OD performance and its robustness. The analysis results show that the reference translunar trajectory can be successfully flown and the navigation performance is strongly dependent on the uncertainties of the ArgoMoonâs Propulsion Subsystem and of the orbit injection
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