Date Fruit Production and Consumption: A Perspective on Global Trends and Drivers from a Multidimensional Footprint Assessment

Date production and consumption is mostly diffused in Middle East and Northern African countries. Date production is linked to the land and water footprint in countries where agricultural land and freshwater are scarce. We estimate the global land, green water, blue water, and water scarcity footprint at the country scale from a production perspective. We show that production trends are increasingly driven by foreign demand. By tracking the international trade dynamics of dates, we map the shift of environmental footprint from the producing to the consuming countries. We find that dates production and consumption are not yet decoupled from the associated environmental burden. Global dates consumption accounted for 1.4 million hectares of agricultural land, 5.8 Gm(3) of green water, 7.5 Gm(3) of blue water, and the related impact on water scarcity reached 358 Gm(3) world equivalent in 2019. The primacy of the economic driver is revealed, indicating that in the case of dates, the environmental sustainability aspects are currently overlooked for the sake of the economic benefit. The time-series analysis provides informative results to support policymakers in the design of mitigation strategies that can help the achievement of the SDGs

The Effectiveness of Clinical Colloquium Established by the “Drawing Recall” Technique in University Counselling Services for Student Mental Health

An experimental assessment of the effectiveness of university counselling was conducted through the “Stress Drawing Recall” Technique applied before and after a clinical colloquium with 70 uni- versity students of both genders, aged 18 - 35 years, who had requested this service. Another 70 students waiting to undergo the colloquium were interviewed as a control group. Two parallel se- ries of drawings depicting personal stress situations were collected and, after evaluation by three expert judges in “double-blind” conditions, led to establishing five forms of development of the graphic language from the first to second drawing, defined as follows: a) distension, with a reduc- tion in stress indicators and increase in comfort indicators; b) explicit representation of conflict resolution; c) appearance of new elements, with persisting conflict; d) increase in stress indicators; e) invariant or equivalent repetition of the stress drawing. Results showed that students who un- derwent the clinical colloquium (experimental group) changed their stress drawings mainly in the direction of distension and conflict resolution, while the control group had more invariant or equivalent repetition of the stress situation ( X42 = 62.77; p < 0.001). The events depicted in the stress drawings were divided into three categories: a) limited short-term stressful situations due to mainly external agents; b) externally induced stressful situations with intense emotional reso- nance; c) wide-ranging long-lasting stressful situations with great involvement of the self. The participants were divided into: a) very anxious subjects; b) averagely anxious subjects; c) not very anxious subjects, on the basis of their scores on two questionnaires: the MPI (1959) and the STAI (1970). There is a correspondence between the subjects’ level of conflict and extension of the de- picted stress. This confirms the usefulness of the Stress Drawing Recall Technique in psychological counsellin

Perceptions and attitudes toward blue energy and technologies in the Mediterranean area: ASKYOURCITIZENSONBE

An energy transition is needed in order to meet the European pledge of reaching climate neutrality by 2050. This transition cannot ignore the renewable resources available from 70% of the Earth (namely, the oceans and seas). This concept is fundamental for the planet, especially for the Mediterranean area. Marine renewable energies are still under-deployed in the Mediterranean area for many reasons, including legislative constraints, lower energy availability, and technological readiness. An appropriate participatory process including all actors (e.g., policymakers, firms, citizens, and researchers) is necessary for a correct path toward decarbonization. The BLUE DEAL project was conceived and implemented by 12 Mediterranean partners to tackle these issues and set the route for blue energy deployment in the Mediterranean area. Activities already conducted include a survey to probe the perceptions and attitudes of citizens toward blue energy. The survey targeted about 3,000 persons in 12 Mediterranean sites with the aim of bringing citizens into the discussion on future technologies. The results showed that although blue energy is still relatively unknown to the general public (only 42% of respondents were aware of these technologies), there was a general willingness (70%) to host one or more such installations in their areas. Here, we describe our survey method and some empirical results with suggestions for replicability and recommendations on how to use it for policymaking purposes

Alopecia universalis after discontinuation of pegylated interferon and ribavirin combination therapy for hepatitis C: a case report

Abstract For the last decade, the combination therapy of pegylated interferon (Peg-IFN) plus ribavirin (RBV) has been considered as the standard of care treatment for chronic hepatitis C virus (HCV) infection. However, it has been associated with an increased incidence of many adverse cutaneous reactions and emergence of autoantibodies or even autoimmune diseases. We report a case of irreversible alopecia universalis (AU) with complete hair loss extended to the whole body, which started after discontinuation of Peg-IFN/RBV combination therapy for chronic HCV infection. In conclusion, this case represents an uncommon presentation of a common disease. Physicians must be aware of the potential adverse reactions of an antiviral therapy containing IFN, which might occur even after the discontinuation, and fully inform the patient at the beginning of his treatment course. We hope that interferon-free regimens will utterly supplant interferon-based therapy for most or all HCV patients avoiding the emergence of autoimmune manifestations

LCA based circularity indices of systems at different scales: a holistic approach

Many are the definitions of Circular Economy as well as the policies and strategies for its implementation. However, gaps still exist in quantifying the effects of circularity. The existing approaches are usually sector- or product-specific, limited to microscale systems, and/or fail to simultaneously assess the environmental impacts of the studied system. This paper introduces a generally applicable method in which a set of LCA-based indices of circularity are able to detect the effects of circularity/symbiosis strategies on the environmental performance of meso- and macro-systems. These indices quantify the overall system's circularity level by comparing the impacts of a system in which the components interact with each other (with a certain level of circularity) with an equivalent linear system (where no circularity takes place). The method works both on existing and projected systems, being able to track the effects of future circularity policies. This method obviates the limitations and the gaps mentioned above: it applies to meso- and macro-systems, it is not bound to a specific sector, it allows to capture the environmental impacts, and it is sensitive to the temporal dimension. This approach provides a tool to inform managers and policymakers for planning circularity actions and monitor their effectiveness while also capturing the temporal dimension

Benchmarking Marine Energy Technologies Through LCA: Offshore Floating Wind Farms in the Mediterranean

Floating wind turbines are a valid option for offshore wind farms in the Mediterranean, where the sea-floor falls off rapidly with distance from the coastline. The present study concerns a Life Cycle Assessment of the environmental performance of two types of floating wind turbine. Greenhouse gas emissions of two standard models (raft-buoy and spar-buoy, 154&nbsp;m rotor diameter, 6&nbsp;MW installed power) were estimated in terms of Global Warming Potential (t CO2eq) with the aim of determining a benchmark for evaluating the performance of similar offshore wind farms. Thus, the aim of the paper was to create a benchmark for the design of innovative technologies, such as those developed by specialist companies, and to verify the validity of new designs and technologies in terms of avoided greenhouse gas emissions. The results show that the Carbon Intensity of Electricity of a single floating wind turbine varies in the range 26–79&nbsp;g CO2eq·kWh−1, averaging 49&nbsp;g CO2eq·kWh−1, in line with other studies of offshore wind turbines and other renewable energy sources (such as onshore wind and photovoltaic). Extension of our study to the whole life cycle, including manufacturing, assembly and installation, maintenance and material replacement and a hypothetical decommissioning and end-of-life, showed that wind farms are among the most promising marine renewable energy technologies for the Mediterranean

Lifecycle environmental impact assessment of an overtopping wave energy converter embedded in breakwater systems

Overtopping breakwater systems are among the most promising technologies for exploiting wave energy to generate electricity. They consist in water reservoirs, embedded in piers, placed on top of ramps, higher than sea-level. Pushed by wave energy, seawater fills up the reservoirs and produces electricity by flowing back down through low headhydro turbines. Different overtopping breakwater systems have been tested worldwide in recent years. This study focuses on the Overtopping BReakwater for Energy Conversion (OBREC) system that has been implemented and tested in the harbor of Naples (Italy). The Life Cycle Assessment of a single replicable module of OBREC has been performed for analyzing potential environmental impacts, in terms of Greenhouse Gas Emissions, considering construction, installation, maintenance, and the operational phases. The Carbon Footprint (i.e., mass of CO2eq) to build wave energy converters integrated in breakwater systems has been estimated, more specifically the "environmental investment" (i.e., the share of Carbon Footprint due to the integration of wave energy converter) needed to generate renewable electricity has been assessed. The Carbon Intensity of Electricity (i.e., the ratio between the CO2eq emitted and the electricity produced) has been then assessed in order to demonstrate the profitability and the opportunity to foster innovation in the field of blue energy. Considering the impact for implementing an operational OBREC module (Carbon Footprint = 1.08 t CO2eq; Environmental Investment = 0.48 t CO2eq) and the electricity production (12.6 MWh/year per module), environmental benefits (avoided emissions) would compensate environmental costs (i.e., Carbon Footprint; Environmental Investment) those provided within a range of 25 and 13 months respectively

Analysis of the influence of the GPS errors occurred while collecting electrode coordinates on the electrical resistivity of tumuli

In archaeological applications the accurate reconstruction of buried structures is mandatory. Electrical resistivity tomography is widely used for this purpose. Nevertheless, resistivity errors could be generated by wrong placement of electrodes. Papers in the literature do not discuss the influence of errors connected with the electrode position location (GPS-error). In this paper the first results of a Monte Carlo simulation analysis of data acquired on a tumulus are presented. The main research questions were: (i) if it is correct to ignore the GPS-error collect, and (ii) if a minimum threshold, that significantly affect the inversion, exists. Results, obtained considering planimetric GPS-errors of about one third of the fixed electrode distances, show that the GPS-errors affect resistivity, but the generated errors/anomalies: (a) are lower than that obtained without considering the topography, and (b) are significant from a numerical point of view, but do not affect the interpretation, being compatible with the soil resistivity ranges

Advantages of manual and automatic computer-aided compared to traditional histopathological diagnosis of melanoma: A pilot study

Background: Cutaneous malignant melanoma (CMM) accounts for the highest mortality rate among all skin cancers. Traditional histopathologic diagnosis may be limited by the pathologists’ subjectivity. Second-opinion strategies and multidisciplinary consultations are usually performed to overcome this issue. An available solution in the future could be the use of automated solutions based on a computational algorithm that could help the pathologist in everyday practice. The aim of this pilot study was to investigate the potential diagnostic aid of a machine-based algorithm in the histopathologic diagnosis of CMM. Methods: We retrospectively examined excisional biopsies of 50 CMM and 20 benign congenital compound nevi. Hematoxylin and eosin (H&amp;E) stained WSI were reviewed independently by two expert dermatopathologists. A fully automated pipeline for WSI processing to support the estimation and prioritization of the melanoma areas was developed. Results: The spatial distribution of the nuclei in the sample provided a multi-scale overview of the tumor. A global overview of the lesion's silhouette was achieved and, by increasing the magnification, the topological distribution of the nuclei and the most informative areas of interest for the CMM diagnosis were identified and highlighted. These silhouettes allow the histopathologist to discriminate between nevus and CMM with an accuracy of 96% without any extra information. Conclusion: In this study we proposed an easy-to-use model that produces segmentations of CMM silhouettes at fine detail level

Autochthonous cases of mucosal leishmaniasis in Northeastern Italy: clinical management and novel treatment approaches

Mucosal leishmaniasis (ML) is a rare clinical variant of tegumentary leishmaniasis in Mediterranean Europe. Here we report on three autochthonous cases of head and neck ML in patients living in Northeastern Italy. Patients presented with non-specific, long-standing symptoms of upper respiratory tract involvement, mimicking other diseases. Parasitological diagnosis was reached by histopathology, immunohistochemistry and molecular biology on tissue specimens. Leishmania infantum was identified by molecular typing in all three cases. All patients reached a complete remission with protracted multivalent antileishmanial drugs; in one case, a novel approach of combined medical and endoscopic surgical treatment was carried out. High clinical suspicion led to a prompt diagnosis and deployment of a multivalent treatment. ML should be considered in the differential diagnosis of nasal, oral, and pharyngolaryngeal lesions in endemic areas. A prompt diagnosis is mandatory to establish a correct management; different antileishmanial medications as well as endoscopic surgical options may be required to reach a complete remission