Cosmology without inflation

We propose a new cosmological paradigm in which our observed expanding phase is originated from an initially large contracting Universe that subsequently experienced a bounce. This category of models, being geodesically complete, is non-singular and horizon-free, and can be made to prevent any relevant scale to ever have been smaller than the Planck length. In this scenario, one can find new ways to solve the standard cosmological puzzles. One can also obtain scale invariant spectra for both scalar and tensor perturbations: this will be the case, for instance, if the contracting Universe is dust-dominated at the time at which large wavelength perturbations get larger than the curvature scale. We present a particular example based on a dust fluid classically contracting model, where a bounce occurs due to quantum effects, in which these features are explicit.Comment: 8 pages, no figur

combining first-principles with deep neural networks

JP acknowledges PhD grant SFRD/BD14610472019, Fundação para a Ciência e Tecnologia (FCT).Hybrid modeling combining First-Principles with machine learning is becoming a pivotal methodology for Biopharma 4.0 enactment. Chinese Hamster Ovary (CHO) cells, being the workhorse for industrial glycoproteins production, have been the object of several hybrid modeling studies. Most previous studies pursued a shallow hybrid modeling approach based on threelayered Feedforward Neural Networks (FFNNs) combined with macroscopic material balance equations. Only recently, the hybrid modeling field is incorporating deep learning into its framework with significant gains in descriptive and predictive power.publishersversionpublishe

Evaluation of moisture sources for the Central European summer flood of May/June 2013 based on regional climate model simulations

Heavy precipitation affected Central Europe in May/June 2013, triggering damaging floods both on the Danube and the Elbe rivers. Based on a modelling approach with COSMO-CLM, moisture fluxes, backward trajectories, cyclone tracks and precipitation fields are evaluated for the relevant time period 30 May–2 June 2013. We identify potential moisture sources and quantify their contribution to the flood event focusing on the Danube basin through sensitivity experiments: Control simulations are performed with undisturbed ERA-Interim boundary conditions, while multiple sensitivity experiments are driven with modified evaporation characteristics over selected marine and land areas. Two relevant cyclones are identified both in reanalysis and in our simulations, which moved counter-clockwise in a retrograde path from Southeastern Europe over Eastern Europe towards the northern slopes of the Alps. The control simulations represent the synoptic evolution of the event reasonably well. The evolution of the precipitation event in the control simulations shows some differences in terms of its spatial and temporal characteristics compared to observations. The main precipitation event can be separated into two phases concerning the moisture sources. Our modelling results provide evidence that the two main sources contributing to the event were the continental evapotranspiration (moisture recycling; both phases) and the North Atlantic Ocean (first phase only). The Mediterranean Sea played only a minor role as a moisture source. This study confirms the importance of continental moisture recycling for heavy precipitation events over Central Europe during the summer half year

Has the Universe always expanded ?

We consider a cosmological setting for which the currently expanding era is preceded by a contracting phase, that is, we assume the Universe experienced at least one bounce. We show that scalar hydrodynamic perturbations lead to a singular behavior of the Bardeen potential and/or its derivatives (i.e. the curvature) for whatever Universe model for which the last bounce epoch can be smoothly and causally joined to the radiation dominated era. Such a Universe would be filled with non-linear perturbations long before nucleosynthesis, and would thus be incompatible with observations. We therefore conclude that no observable bounce could possibly have taken place in the early universe if Einstein gravity together with hydrodynamical fluids is to describe its evolution, and hence, under these conditions, that the Universe has always expanded.Comment: 11 pages, LaTeX-ReVTeX, no figures, submitted to PR

Wind gust estimation for Mid-European winter storms: towards a probabilistic view

Three wind gust estimation (WGE) methods implemented in the numerical weather prediction (NWP) model COSMO-CLM are evaluated with respect to their forecast quality using skill scores. Two methods estimate gusts locally from mean wind speed and the turbulence state of the atmosphere, while the third one considers the mixing-down of high momentum within the planetary boundary layer (WGE Brasseur). One hundred and fifty-eight windstorms from the last four decades are simulated and results are compared with gust observations at 37 stations in Germany. Skill scores reveal that the local WGE methods show an overall better behaviour, whilst WGE Brasseur performs less well except for mountain regions. The here introduced WGE turbulent kinetic energy (TKE) permits a probabilistic interpretation using statistical characteristics of gusts at observational sites for an assessment of uncertainty. The WGE TKE formulation has the advantage of a ‘native’ interpretation of wind gusts as result of local appearance of TKE. The inclusion of a probabilistic WGE TKE approach in NWP models has, thus, several advantages over other methods, as it has the potential for an estimation of uncertainties of gusts at observational sites

Adiabatic and entropy perturbations propagation in a bouncing Universe

By studying some bouncing universe models dominated by a specific class of hydrodynamical fluids, we show that the primordial cosmological perturbations may propagate smoothly through a general relativistic bounce. We also find that the purely adiabatic modes, although almost always fruitfully investigated in all other contexts in cosmology, are meaningless in the bounce or null energy condition (NEC) violation cases since the entropy modes can never be neglected in these situations: the adiabatic modes exhibit a fake divergence that is compensated in the total Bardeen gravitational potential by inclusion of the entropy perturbations.Comment: 25 pages, no figure, LaTe

Primordial perturbations in a non singular bouncing universe model

We construct a simple non singular cosmological model in which the currently observed expansion phase was preceded by a contraction. This is achieved, in the framework of pure general relativity, by means of a radiation fluid and a free scalar field having negative energy. We calculate the power spectrum of the scalar perturbations that are produced in such a bouncing model and find that, under the assumption of initial vacuum state for the quantum field associated with the hydrodynamical perturbation, this leads to a spectral index n=-1. The matching conditions applying to this bouncing model are derived and shown to be different from those in the case of a sharp transition. We find that if our bounce transition can be smoothly connected to a slowly contracting phase, then the resulting power spectrum will be scale invariant.Comment: 11 pages, RevTeX 4, 8 figures, submitted to Phys. Rev.

Mapping woody plant community turnover with space-borne hyperspectral data: a case study in the Cerrado

Effective conservation measures require the knowledge on the spatial patterns of species communities and their turnover. This knowledge is, however, many times lacking, particularly so for complex systems. On the other hand, recent developments have resulted in tools that enable the mapping of these patterns from remote sensing data, such as Sparse Generalized Dissimilarity Modelling (SGDM). SGDM is a two-stage approach, which combines a Sparse Canonical Component analysis and a Generalized Dissimilarity Modelling (GDM), thus being designed to deal with high-dimensional data to predict community turnover in GDM. In this study, we use space-borne hyperspectral data to map woody plant community patterns collected in two study sites in the Cerrado (Brazilian savannah), namely, the Parque Estadual da Serra Azul (PESA) in Mato Grosso state and Parque Nacional da Chapada dos Veadeiros (PNCV) in Goiás state. Field data were collected in both study sites, following a systematic sampling scheme adapted for the Cerrado. The Cerrado is the most diverse of all the world's savannahs, and while holding a high diversity and endemism of species, this biome is mostly unprotected and understudied. We used Hyperion data acquired over the two study sites, which were subject to data pre-processing (including radiometric and geometric corrections, as well as correction for sensor errors) and quality screening before analysis. Our models were used to map woody plant community patterns and turnover for the study areas. We also inspected the Hyperion spectral bands which most contributed in the SGDM, for each site. Furthermore, the modelled patterns were interpreted with respect to the ecological characteristics of the respective species, this way further enhancing our understanding of this complex system. This study has demonstrated that this approach is suitable for mapping woody plant communities in heterogeneous systems, based on combined field and space-borne hyperspectral data

Passing through the bounce in the ekpyrotic models

By considering a simplified but exact model for realizing the ekpyrotic scenario, we clarify various assumptions that have been used in the literature. In particular, we discuss the new ekpyrotic prescription for passing the perturbations through the singularity which we show to provide a spectrum depending on a non physical normalization function. We also show that this prescription does not reproduce the exact result for a sharp transition. Then, more generally, we demonstrate that, in the only case where a bounce can be obtained in Einstein General Relativity without facing singularities and/or violation of the standard energy conditions, the bounce cannot be made arbitrarily short. This contrasts with the standard (inflationary) situation where the transition between two eras with different values of the equation of state can be considered as instantaneous. We then argue that the usually conserved quantities are not constant on a typical bounce time scale. Finally, we also examine the case of a test scalar field (or gravitational waves) where similar results are obtained. We conclude that the full dynamical equations of the underlying theory should be solved in a non singular case before any conclusion can be drawn.Comment: 17 pages, ReVTeX 4, 13 figures, minor corrections, conclusions unchange

Lack of Neointimal Proliferation After Implantation of Sirolimus-Coated Stents in Human Coronary Arteries: A Quantitative Coronary Angiography and Three-Dimensional Intravascular Ultrasound Study

BACKGROUND: Restenosis remains an important limitation of interventional cardiology. Therefore, we aimed to determine the safety and efficacy of sirolimus (a cell-cycle inhibitor)-coated BX Velocity stents. METHODS AND RESULTS: Thirty patients with angina pectoris were electively treated with 2 different formulations of sirolimus-coated stents (slow release [SR], n=15, and fast release [FR], n=15). All stents were successfully delivered, and patients were discharged without clinical complications. Independent core laboratories analyzed angiographic and 3D volumetric intravascular ultrasound data (immediately after procedure and at 4-month follow-up). Eight-month clinical follow-up was obtained for all patients. There was minimal neointimal hyperplasia in both groups (11.0+/-3.0% in the SR group and 10.4+/-3.0% in the FR group, P:=NS) by ultrasound and quantitative coronary angiography (in-stent late loss, 0.09+/-0.3 mm [SR] and -0.02+/-0.3 mm [FR]; in-lesion late loss, 0.16+/-0.3 mm [SR] and -0.1+/-0.3 mm [FR]). No in-stent or edge restenosis (diameter stenosis >or=50%) was observed. No major clinical events (stent thrombosis, repeat revascularization, myocardial infarction, or death) had occurred by 8 months. CONCLUSIONS: The implantation of sirolimus-coated BX Velocity stents is feasible and safe and elicits minimal neointimal proliferation. Additional placebo-controlled trials are required to confirm these promising results