208 research outputs found

    High-contrast Ultrabroadband Frontend Source for High Intensity Few-Cycle Lasers

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    An ultrabroadband seed source for high-power, high-contrast OPCPA systems at 800 nm is presented. The source is based on post compression in a hollow-core fiber followed by crossed polarized waves (XPW) filtering and is capable of delivering 80Ό\muJ, 5fs, CEP-stable (0.3rad RMS) pulses with excellent spectral and temporal qualit

    What is the comparative health status and associated risk factors for the MĂ©tis? A population-based study in Manitoba, Canada

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    <p>Abstract</p> <p>Background</p> <p>MĂ©tis are descendants of early 17<sup>th </sup>century relationships between North American Indians and Europeans. This study's objectives were: (1) to compare the health status of the MĂ©tis people to all other residents of Manitoba, Canada; and (2) to analyze factors in predicting the likelihood of diabetes and related lower limb amputation.</p> <p>Methods</p> <p>Using de-identified administrative databases plus the MĂ©tis Population Database housed at the Manitoba Centre for Health Policy, age/sex-adjusted rates of mortality and disease were calculated for MĂ©tis (n = 73,016) and all other Manitobans (n = 1,104,672). Diseases included: hypertension, arthritis, diabetes, ischemic heart disease (age 19+); osteoporosis (age 50+); acute myocardial infarction (AMI) and stroke (age 40+); total respiratory morbidity (TRM, all ages). Using logistic regression, predictors of diabetes (2004/05-2006/07) and diabetes-related lower-limb amputations (2002/03-2006/07) were analyzed.</p> <p>Results</p> <p>Disease rates were higher for MĂ©tis compared to all others: premature mortality before age 75 (4.0 vs. 3.3 per 1000, p < .001); total mortality (9.7 vs. 8.4 per 1000, p < .001); injury mortality (0.58 vs. 0.51 per 1000, p < .03); Potential Years of Life Lost (64.6 vs. 54.6 per 1000, p < .001); all-cause 5-year mortality for people with diabetes (20.8% vs. 18.6%, p < .02); hypertension (27.9% vs. 24.8%, p < .001); arthritis (24.2% vs. 19.9%, p < .001), TRM (13.6% vs. 10.6%, p < .001); diabetes (11.8% vs. 8.8%, p < .001); diabetes-related lower limb amputation (24.1 vs. 16.2 per 1000, p < .001); ischemic heart disease (12.2% vs. 8.7%, p < .001); osteoporosis (12.2% vs. 12.3%, NS), dialysis initiation (0.46% vs. 0.34%, p < .001); AMI (5.4 vs. 4.3 per 1000, p < .001); stroke (3.6 vs. 2.9 per 1000, p < .001). Controlling for geography, age, sex, income, continuity of care and comorbidities, MĂ©tis were more likely to have diabetes (aOR = 1.29, 95% CI 1.25-1.34), but not diabetes-related lower limb amputation (aOR = 1.13, 95% CI 0.90-1.40, NS). Continuity of care was associated with decreased risk of amputation both provincially (aOR = 0.71, 95% CI 0.62-0.81) and for MĂ©tis alone (aOR = 0.62, 95% CI 0.40-0.96).</p> <p>Conclusion</p> <p>Despite universal healthcare, MĂ©tis' illness and mortality rates are mostly higher. Although elevated diabetes risk persists for the MĂ©tis even after adjusting for sociodemographic, healthcare and comorbidity variables, the risk of amputation for MĂ©tis appears more related to healthcare access rather than ethnicity.</p

    Efficient cross polarized wave generation for compact, energy-scalable, ultrashort laser sources

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    International audienceThe generation of high contrast and ultrashort laser pulses via a compact and energy-scalable cross polarized wave filter is presented. The setup incorporates a waveguide spatial filter into a single crystal XPW configuration, enabling high energy and high intensity transmission, efficient contrast enhancement and pulse shortening at the multi-mJ level. Excellent XPW conversion of up to 33% (global efficiency: 20%, intensity transmission: 40%) led to an output energy of 650 ?J for an input of 3.3 mJ. Additionally, efficient conversion under specific input phase conditions, allowed pulse shortening from 25 fs to 9.6 fs, indicating the prospective application of this setup as a high energy, ultrabroad laser source. © 2010 Optical Society of America

    Energy-scalable temporal cleaning device for femtosecond laser pulsesbased on cross-polarized wave generation

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    International audienceWe report on a compact energy-scalable device for generating high-fidelity femtosecond laser pulses based on spatial filtering through a hollow-core fiber followed by a nonlinear crystal for crosspolarized wave (XPW) generation. This versatile device is suited for temporal pulse cleaning over a wide range of input energies (from 0.1 to >10 mJ) and is successfully qualified on different ultrafast laser systems. Full characterization of the XPW output is presented. In particular, we demonstrate the generation of 1.6 mJ energy pulses starting from 11 mJ input pulse energy. The temporal contrast of the pulses is enhanced by more than 4 orders of magnitude. In addition, pulse shortening from 40 fs down to 15 fs Fourier-transform limit yields an overall peak-power transmission of up to 50%. This device not only serves as an integrated pulse contrast filter inside an ultrafast laser amplifier but also as a simple back-end solution for temporal post-compression of amplified pulses

    Informaticawetenschappen in het leerplichtonderwijs

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    Dit standpunt bepleit en beargumenteert de noodzaak om elke jongere een opleiding informaticawetenschappen aan te bieden die toelaat om ’informaticavaardig’ te worden. Informaticavaardigheid gaat verder dan louter ‘digitale geletterdheid’, en houdt ook in dat de jongere in staat moet zijn ‘computationeel’ te denken. Computers zijn onmisbaar geworden, zowel in het professionele leven als in de privĂ©sfeer. Om de technologische evolutie te kunnen volgen is het van groot belang dat alle jongeren niet alleen de bestaande technologie leren gebruiken, maar ook de onderliggende werking leren begrijpen. Om de technologische evolutie te kunnen sturen, is het nodig dat voldoende jongeren in staat en gemotiveerd zijn om nieuwe technologie te creĂ«ren. Om deze doelstellingen te realiseren, dient het onderwijs van de informatica in het leerplichtonderwijs grondig hervormd te worden. In het basis- en secundair onderwijs dient een basisopleiding informaticawetenschappen opgenomen te worden, waarop in specifieke STEM richtingen voortgebouwd wordt. Een nieuw leerprogramma, goed opgeleide leraars en een goede informatica-infrastructuur zijn broodnodig. Ons leerplichtonderwijs is de belangrijkste actor om volgende generaties voor te bereiden op het leven, zowel professioneel als privĂ©. De digitalisering van onze maatschappij kan haar voordelen alleen waarmaken als het onderwijs aangepast is aan deze digitale realiteit. Informatica- wetenschappen is een autonome wetenschap geworden met haar eigen manier van denken, en haar eigen basisbegrippen, te vergelijken met wiskunde, natuurkunde, en andere wetenschap- pen, die haar plaats in het onderwijs verdient. Het moet duidelijk zijn dat het hier niet gaat over het onderwijs van de traditionele vakken met de steun van informaticahulpmiddelen maar wel over de informaticawetenschappen zelf als vormend vak. Dit standpunt kwam tot stand binnen een werkgroep, opgericht door de KVAB en de Jonge Academie en samengesteld met leden uit diverse academische disciplines, onderwijsdeskundi- gen en actoren uit de bedrijfswereld
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