A case of Nocardia transvalensis pneumonia in a 19-year-old cystic fibrosis patient

Nocardia species is rarely encountered in cystic fibrosis (CF) patients. Its isolation usually implies colonization. Of all other Nocardia species, Nocardia transvalensis is very unusual and is clinically distinguishable because of its resistance to aminoglycosides, a standard antinocardial therapy. We report a case of N. transvalensis pulmonary infection in a CF patient

Pumpless arteriovenous carbon dioxide removal: A novel simplified strategy for severe asthma in children

Status asthmaticus unresponsive to pharmacotherapy is conventionally managed with mechanical ventilation, which has its inherent challenges due to barotrauma, dynamic hyperinflation and autopositive end-expiratory pressure (auto-PEEP). Extracorporeal membrane oxygenation has been used as a last resort in respiratory failure due to refractory asthma; however, it entails many complications. In contrast, arteriovenous carbon dioxide removal (AVCO2R) is a novel strategy that has been shown to be highly effective in adults with acute respiratory failure. Only one pediatric case series of pediatric asthma managed with AVCO2R have been published so far. We herein report a case of severe asthma in a 9-year-old boy who developed severe hypercapnia (PCo2 97 mmHg) and acidosis (pH 7.09) despite being on mechanical ventilation. Within 4 h of initiation of AVCO2R, PCo2 drastically reduced to near-normal levels. He was discharged on day 9 of hospital stay without any complications

Pumpless arteriovenous carbon dioxide removal: A novel simplified strategy for severe asthma in children

Status asthmaticus unresponsive to pharmacotherapy is conventionally managed with mechanical ventilation, which has its inherent challenges due to barotrauma, dynamic hyperinflation and autopositive end-expiratory pressure (auto-PEEP). Extracorporeal membrane oxygenation has been used as a last resort in respiratory failure due to refractory asthma; however, it entails many complications. In contrast, arteriovenous carbon dioxide removal (AVCO2R) is a novel strategy that has been shown to be highly effective in adults with acute respiratory failure. Only one pediatric case series of pediatric asthma managed with AVCO2R have been published so far. We herein report a case of severe asthma in a 9-year-old boy who developed severe hypercapnia (PCo2 97 mmHg) and acidosis (pH 7.09) despite being on mechanical ventilation. Within 4 h of initiation of AVCO2R, PCo2 drastically reduced to near-normal levels. He was discharged on day 9 of hospital stay without any complications

Developing an effective inpatient learning climate

12 month embargo; published online: 11 December 2019This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]