Analysis on Role of E-Commerce in Reducing Operational Cost

E-commerce means electronic commerce. E-commerce involves carrying on a business with help of the internet and by using the information technology like Electronic Data Interchange (EDI). E-commerce relates to a websites of the vendor on the internet, who trades products or services directly to the customer from the portal. The portal uses a digital shopping cart or digital basket system and allows payment through credit, debit card or EFT (Electronic fund transfer) payments

A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging

An electronically active and spectral sensitive fluorescent “turn-on” chemosensor (BTP-1) based on the benzo-thiazolo-pyrimidine unit was designed and synthesized for the highly selective and sensitive detection of Fe³⁺ from aqueous medium. With Fe³⁺, the sensor BTP-1 showed a remarkable fluorescence enhancement at 554 nm (λex=314 nm) due to the inhibition of photo-induced electron transfer. The sensor formed a host-guest complex in 1:1 stoichiometry with the detection limit down to 0.74 nM. Further, the sensor was successfully utilized for the qualitative and quantitative intracellular detection of Fe³⁺ in two liver cell lines i.e., HepG2 cells (human hepatocellular liver carcinoma cell line) and HL-7701 cells (human normal liver cell line) by a confocal imaging technique

PRESCRIPTION ANALYSIS OF HYPERTENSIVE PATIENTS AND AWARENESS AMONG PHYSICIAN REGARDING ANTIHYPERTENSIVE DRUG

Objective: This study was conducted to analyze prescriptions of the hypertensive patient and to determine the awareness of physicians regarding antihypertensive drugs. Methods: Prepare a questionnaire by the pilot study on five physicians. Review and finalized the questionnaire after discussion with pharmacologist. The answers were seek for awareness. Moreover the prescription of 30 patients was collected from the same physician who has undertaken the awareness regarding Antihypertensive Drugs. Study was conducted during Oct-2019 to Dec 2019. Results: Average 83% awareness was found in the physician regarding antihypertensive drugs. Lack of awareness regarding diabetes and in ulcer patients was observed. Highest drug is given i.e. β blockers in antihypertensive patients. To determine the irrationality in the prescription of hypertensive patients. Conclusion: To determine the FDC`s given to hypertensive patients. To determine the type of antihypertensive drugs given to patients

Preparation, spectral study and antimicrobial activity of binary Co(II) complexes derived from 2’-hydroxy chalcones

ABSTRACT. The present work comprises preparation, characterization, thermal behavior and growth inhibitory activity of some novel Co(II) complexes derived from substituted (E)-1-(1-hydroxy-4-iodonaphthalen-2-yl)-3-phenylprop-2-en-1-one (L1) and (E)-1-(4-bromo-1-hydroxynaphthalen-2-yl)-3-phenylprop-2-en-1-one (L2-L6). Newly synthesized metal-ligand complexes were structurally confirmed with suitable spectroscopic technique such as FT-IR, EPR, NMR (both 1H and 13C). XRD analysis for complex C1 confirmed the crystal system; tetragonal and space group; P 42/n: 2 with unit cell dimensions a, b = 13.3516 Å, c = 10.8009 Å; α, β, γ = 90o. The IR and EPR study demonstrated that interaction between metal ions and ligand occurs through carbonyl oxygen and hydroxyl oxygen. From the values of magnetic moment (μ) it was observed that synthesized complexes (C1-C6) are paramagnetic with three unpaired electrons contain one electron in t2g orbital and two electrons in eg orbitals. Further all these complexes have been evaluated in-vitro for their antimicrobial activity against the Gram positive bacteria Staphylococcus aureus, Gram negative bacteria Escherichia coli and the yeast Candida albicans. The complex C1 showed the significant antimicrobial activity, whereas the complexes C2, C4, C5 and C6 are moderately active against the tested pathogens. The antimicrobial data revealed that growth inhibitory activities of complexes were enhanced comparatively than its respective ligands. The enhanced antimicrobial activity is attributed to the presence of halogens (Br, Cl, I) and hydroxyl (OH) active substituents associated with the basic nucleus of complexes. Therefore, the present study helps to develop a new class of antimicrobial analogues.                     KEY WORDS: Metal complexes synthesis, 1,3-Diaryl-2-propene-1-one, Crystal structure, Thermal properties, Antimicrobial activity   Bull. Chem. Soc. Ethiop. 2021, 35(3), 513-524. DOI: https://dx.doi.org/10.4314/bcse.v35i3.

Endophytic Mycoflora of Indian Medicinal Plant, Terminalia arjuna and their Biological Activities

Studies were undertaken to isolate, identify and evaluate the biological activities of endophytic mycoflora of Indian medicinal plant, Terminalia arjuna. A total of 20 isolates of endophytic fungi were obtained from the leaves, twigs and bark tissues of the Terminalia arjuna. Out of 20, six isolates exhibited promising antibacterial, antifungal and anti-inflammatory activities when cultivated at shake flask level. The selected isolates were identified on the basis of morphology and ITS gene sequencing. Three isolates, designated as TA BA 1, TA L1 and TA L2 were identified as Aspergillus flavus whereas; the remaining three endophytic fungi were identified as Diaporthe arengae (TA TW2), Alternaria Sp. (TA TW1) and Lasiodiplodia theobromae (TA BA2). Aspergillus flavus was found as the predominant endophyte in leaves and bark tissues of the plant. The crude extract of the test isolates showed considerable antimicrobial activity against common human bacterial (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, Salmonella abony and Bacillus subtilis) and fungal (Candida albicans, Aspergillus niger and Penicilium sp.) pathogens. The extract of Diaporthe arengae (TA TW2) significantly reduced the concentration of DPPH free radical as percent DPPH scavenging activity was found to be highest (69.56%) in comparison with other isolates. The % inhibition of hemolysis of RBCs was found to be highest (82.85%) with Diaporthe arengae (TA TW2) in comparison (83.26%) with standard drug (Ibuprofen). Among all, the extract of the Diaporthe arengae (TA TW2) showed excellent biological activities and hence was subjected to further characterization. The phytochemical investigation of the extract revealed the presence of terpenoids as the major phytoconstituents which was supported by TLC and UV spectroscopic studies. The results indicate that the isolated endophytes could be the valuable source of these bioactive molecules with diverse biological activities. The bioactivities may be attributed to the terpenoids present in the endophytic extract

Variable - temperature scanning optical and force microscope

The implementation of a scanning microscope capable of working in confocal, atomic force and apertureless near field configurations is presented. The microscope is designed to operate in the temperature range 4 - 300 K, using conventional helium flow cryostats. In AFM mode, the distance between the sample and an etched tungsten tip is controlled by a self - sensing piezoelectric tuning fork. The vertical position of both the AFM head and microscope objective can be accurately controlled using piezoelectric coarse approach motors. The scanning is performed using a compact XYZ stage, while the AFM and optical head are kept fixed, allowing scanning probe and optical measurements to be acquired simultaneously and in concert. The free optical axis of the microscope enables both reflection and transmission experiments to be performed.Comment: 24 pages, 9 figures, submitted to the journal "Review of Scientific Instruments

Traditional Medicolore in Badwani District (M.P.) India

The study concerns significant ethnobotanical information of 25 plant species belonging to 25 genera and 19 families traditionally used by the aborigines and rural folks of Badwani district, Of these 21 species are being noted for the first time from Indian region.  Madhya Pradesh (India) to treat various human diseases such as, impotency, intestinal worms, fever, constipation, ring worms, eczema, hepatitis, menstrual complaints, urinary complaints, migraine stomach-ache, bone fracture, lactation, piles, night blindness, pregnancy and abortion, etc.,This paper highlights traditional uses of plants used by the rural and tribal people. The district is inhabited with tribes viz., Gond, Baiga, Koraku, Bhariaya, Halba, Bhil, Kaul and Pawara. The population of the region is predominantly rural and tribal having considerable knowledge about ambient plant wealth and their traditional utility. The present work is an attempt to collect document and evaluate the ethnomedicinal claims in the areas under study. Key words: Ethnomedicine, Badwani District, Madhya Pradesh P. S. Patil. Traditional Medicolore in Badwani District (M.P.) India. J Phytol 2/12 (2010) 49-53

1-(2,4-Dichloro­phen­yl)-3-(4-methyl­phen­yl)prop-2-en-1-one

The mol­ecule of the title compound, C16H12Cl2O, adopts an E configuration. The dihedral angle between the two benzene rings is 42.09 (5)°. In the crystal structure, mol­ecules are linked into a three-dimensional framework by weak C—H⋯O inter­actions and by C—H⋯π inter­actions involving the methyl­phenyl ring