465 research outputs found

    Strain dependence of ultrasound speed in bovine articular cartilage under compression in vitro

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    Author name used in this publication: H. Y. LingAuthor name used in this publication: Y. P. ZhengAuthor name used in this publication: S. G. PatilTitle on author's file: Study on strain dependence of ultrasound speed in bovine articular cartilage under compression in vitro2007-2008 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Nidra - A Literary Review

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    Sleep plays a key role in the survival of a human being. Sleep deprivation has more negative effects on the quality of life of an individual than food deprivation. More than 1/3rd of a human’s life is spent in sleeping. Sleep is one of the 13 Adharaniya Vegas,[1] i.e., the urges that should not be controlled. Sleep is also one the Trayopasthambhas according to Ayurveda[2] i.e., the three pillars of life. Sleeplessness has been mentioned as a symptom in multiple diseases

    Intraosseous acinic cell carcinoma

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    Acinic cell carcinoma is an uncommon low-grade malignant tumor of salivary glands. It was first described by Nasse in 1892, arising in parotid salivary gland. Salivary gland tumors are also known to develop within jaw bones, arising within the jaw as a primary central lesion, and are extremely rare with only a few cases reported. We present a rare case report of 65-year-old woman with intraosseous acinic cell carcinoma of left side of the mandible.Key words: Acinic cell carcinoma, central tumor of mandible, intraosseous acinic cell carcinom

    Possible Hypoxia Signaling Induced Alteration of Glucose Homeostasis in Rats Exposed to Chronic Intermittent Hypoxia - Role of Antioxidant (Vitamin C) and Ca2+ Channel Blocker (Cilnidipine)

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    Background: Hyperglycemia is found to be a regulator of HIF-1α gene expression but the regulation of HIF-1α on glucose homeostasis is unclear. Objective: To determine whether chronic intermittent hypoxia (CIH) alters glucose regulation and such alterations can revert through treatments with either antioxidant (vitamin c) or calcium channel blocker (cilnidipine) in male albino rats. Methods: The rats were divided into six groups i.e. normoxia (21% oxygen), CIH (10% oxygen with cycle time 3:1.5; 8h/day), normoxia with vitamin c (50 mg /100g. b.wt, orally), CIH with vitamin c, normoxia with cilnidipine (1 mg/kg/day; ip) and CIH with cilnidipine. Serum MDA, HIF-1α, fasting plasma glucose, insulin, GTT, HOMA-IR and insulinogenic index were evaluated. Results: Serum HIF-1α and MDA concentration in rats exposed to CIH increased significantly whereas simultaneous CIH with vitamin c and CIH with cilnidipine treatment show reversion of both serum HIF- 1α and MDA concentrations towards normoxic status. CIH rats showed increased fasting glucose level with unchanged plasma insulin level but both vitamin c and cilnidipine treatment improved the status. Elevated HOMA-IR and insulinogenic index along with impaired GTT were found in CIH groups although vitamin c and cilnidipine improved the glucose homeostasis in CIH exposed rats. Conclusion: CIH induces over production of reactive oxygen species as well as hyper activities of sympathetic N-type Ca2+ channels possibly through HIF 1-α expression and influence on insulin signaling by causing hyperglycemia, glucose intolerance and insulin resistance in rats. Simultaneous treatment with vitamin c or cilnidipine improves glucose homeostasis in CIH exposed rats

    Measurement of depth-dependence and anisotropy of ultrasound speed of bovine articular cartilage in vitro

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    Author name used in this publication: S. G. PatilAuthor name used in this publication: Y. P. ZhengAuthor name used in this publication: J. Y. WuAuthor name used in this publication: J. Shi2004-2005 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    The Relationship Between Life Course Factors, Parental Demographics, Dental Coping Beliefs and Its Influence on Adolescents Dental Visit: a Cross Sectional Study

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    BACKGROUND: Oral Disease is a multifactorial one that includes behavioral and cultural components, and the severity of the disease depends on regularity of dental visits. The purpose of the study was to evaluate the relationship between parental demographics, life course factors, dental coping beliefs with therecent dental attendance among adolescents in Udupi Taluk.METHODS: Three hundred and fifty adolescents aged 16-19 years from four randomly selected schools in Udupi Taluk participated in this cross sectional study. Information was obtained regarding their parental demographics, their early life course, dental coping beliefs and recent dental attendance. Bivariate followed by multiple logistic regression analysis was performed to elicit variables which predict recent dental attendance.RESULTS: Out of the 324 adolescents who completed the questionnaire, 25.3% reported visiting a dentist within a period of one year. Childhood dental visit, childhood dental experience, housing, internal and external locus of control and self-efficacy were significantly associated with recent dental visit (p<0.05). Participants who lived in cement/brick houses were 4.3 times more likely to visit a dentist within one year compared to those living in hut/mud/combined houses (p<0.05). Adolescents with lower external (OR= 0.11, P<0.003) and low internal (OR=0.05, P<0.001) locus of control had lower odds of visiting a dentist within a year when compared with those having higher locus of control.CONCLUSION: Childhood financial hardships, childhood dental visits and experiences and dental coping beliefs affect dental attendance pattern during adolescence. These factors should be considered while tailoring interventions to promote the oral health and dental attendance behaviors of adolescents.KEYWORDS:Coping beliefs, dental attendance, life course, locus of control, social clas

    Dynamic depth-dependent osmotic swelling and solute diffusion in articular cartilage monitored using real-time ultrasound

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    Author name used in this publication: Y. P. ZhengAuthor name used in this publication: J. ShiAuthor name used in this publication: S. G. Patil2003-2004 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Instability of black hole formation under small pressure perturbations

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    We investigate here the spectrum of gravitational collapse endstates when arbitrarily small perfect fluid pressures are introduced in the classic black hole formation scenario as described by Oppenheimer, Snyder and Datt (OSD) [1]. This extends a previous result on tangential pressures [2] to the more physically realistic scenario of perfect fluid collapse. The existence of classes of pressure perturbations is shown explicitly, which has the property that injecting any smallest pressure changes the final fate of the dynamical collapse from a black hole to a naked singularity. It is therefore seen that any smallest neighborhood of the OSD model, in the space of initial data, contains collapse evolutions that go to a naked singularity outcome. This gives an intriguing insight on the nature of naked singularity formation in gravitational collapse.Comment: 7 pages, 1 figure, several modifications to match published version on GR

    Effective theories of single field inflation when heavy fields matter

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    We compute the low energy effective field theory (EFT) expansion for single-field inflationary models that descend from a parent theory containing multiple other scalar fields. By assuming that all other degrees of freedom in the parent theory are sufficiently massive relative to the inflaton, it is possible to derive an EFT valid to arbitrary order in perturbations, provided certain generalized adiabaticity conditions are respected. These conditions permit a consistent low energy EFT description even when the inflaton deviates off its adiabatic minimum along its slowly rolling trajectory. By generalizing the formalism that identifies the adiabatic mode with the Goldstone boson of this spontaneously broken time translational symmetry prior to the integration of the heavy fields, we show that this invariance of the parent theory dictates the entire non-perturbative structure of the descendent EFT. The couplings of this theory can be written entirely in terms of the reduced speed of sound of adiabatic perturbations. The resulting operator expansion is distinguishable from that of other scenarios, such as standard single inflation or DBI inflation. In particular, we re-derive how certain operators can become transiently strongly coupled along the inflaton trajectory, consistent with slow-roll and the validity of the EFT expansion, imprinting features in the primordial power spectrum, and we deduce the relevant cubic operators that imply distinct signatures in the primordial bispectrum which may soon be constrained by observations.Comment: (v1) 25 pages, 1 figure; (v2) references added and typos corrected, to appear in Journal of High Energy Physic
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