Dietary Practices Among Type 2 Diabetes Patients Visiting a Non-communicable Disease (NCD) Clinic in a District of Western India: A Cross-Sectional Study

BACKGROUND AND AIMS: Diabetes is becoming a major public health problem in the country. One of the most important lifestyle modifications necessary for diabetic patients is maintaining healthy dietary choices. These modifications in dietary practices are supposed to be followed lifelong, along with medication, for better glycemic control. Despite understanding the importance of dietary control and physical activity in the management of diabetes, adherence to these practices is poor. This study aimed to assess the dietary practices of type 2 diabetes mellitus (T2DM) patients and various factors that determine adherence to these healthy dietary practices. The secondary objective was to find the perceptions of participants about the role of diet in controlling diabetes and to find the perception-practice gap among study participants. METHODOLOGY: It was a hospital-based cross-sectional study conducted among 450 T2DM patients visiting the non-communicable disease (NCD) clinics of tertiary care hospitals and community health centres (CHCs) of the study district. Dietary practice was assessed using a modified UK Diabetes and Diet Questionnaire (UKDDQ), considering the food patterns in the study area. Statistical tests like chi-square and ordinal logistic regression were applied using Jamovi software for univariate and multivariate analyses. RESULTS: The healthiest food choices were abstinence from alcohol consumption (100%), avoiding processed meat (92.21%), high-fibre breakfast (70.4%), and daily consumption of vegetables (68.2%). Improper dietary practices were regular sugary drinks (38%) and high-glycemic-index food items (22.4%). The mean (SD) of the composite score was 68.02 (8.7) and the median score (interquartile range (IQR)) was 69 (60-76). Tertile analysis of the composite score revealed that with the increase in age, patients were less likely to be in the intermediate or upper tertile score (β = -0.0219, p = 0.016). Being female (odds ratio (OR) =0.603, CI: 0.395-0.917, p = 0.019) and living in a three-generation family made the patients less likely to be in the upper tertile score. CONCLUSION: Nearly half of the participants had an overall healthy score. Dietary practices were healthy among the participants of lower ages, males, and those living in nuclear and joint families. The highest perception-practice gap was seen for fruit and rice consumption

CREDIT POINTS EXCHANGE

The present disclosure relates to a method and a system for establishing a credit exchange platform that allows users to effectively utilize the unused credit points. In an embodiment, the present disclosure discloses aggregating the credit points accumulated on multiple credit cards using the credit exchange platform. Further, the disclosure suggests allowing the users to redeem the aggregated credit points or sell them to a different user, resulting in effective and best use of the credit points

Fixed point results in Ab-metric space

We derive some fixed point results in Ab- metric space in which map need not be continuous. In addition, we find fixed point and common fixed theorems having rational expressions in the contractive condition. Our results extend and improve various results from the current existing literature. Also, we provide examples.Publisher's Versio

Xanthogranulomatous pyelonephritis: a case review of two cases

Xanthogranulomatous pyelonephirits is a chronic destructive granulomatous inflammation of the renal parenchyma. It was first described by Schlagenhaufer in 1916 and then Oberling named the disease as Xanthogranulomatous pyelonephritis in 1935. It represents 1% of all renal infections. In this report we present two cases of Xanthogranulomatous pyelonephritis along with radiological assessment

HYSTEROSALPINGOGRAPHY: TECHNIQUE AND APPLICATIONS (VIEW)

Hysterosalpingography (HSG) is the radiographic evaluation of the uterine cavity and fallopian tubes after the administration of a radio-opaque medium through the cervical canal. The first HSG was performed in 1910 and was considered to be the first special radio¬logic procedure. A properly performed HSG can de¬tect the contour of the uterine cavity and the width of the cervical canal. Further contrast medium injection will outline the cornua isthmic and ampullary portions of the tubes, and will show the degree of spillage. If a properly performed HSG shows no uterine cavity abnormality, it is very unlikely that other modalities would do so. Although this procedure is considered diagnostic, there may also be a possible therapeutic benefit from the flushing effect. Indications and Contraindications HSG is used predominantly in the evaluation of in-fertility. Despite the arrival of newer imaging modalities, HSG still remains the best procedure to image the fallopi¬an tubes. Although evaluating feminine infertility, with or without the presence of repeated miscarriages, is the main indication for this method, it can also be used in other cas-es, such as pain in the pelvis tract, congenital or anatomic abnormalities, anomalies of the menstrual cycle, and ab-normal menses. Also, it is sometimes used as a preoper-ative control for women who are about to have uterine or tubal surgery. Soares and coworkers showed that HSG had a sensitivity of 58% and a positive-predictive value of 28.6% for polypoid lesions, and a sensitivity of 0% for endometrial hyperplasia. The same study showed HSG to have a sensitivity of 44.4% for uterine malformations, and a sensitivity of 75% for the detection of intrauterine adhesions. The main contraindication of the examination is possible pregnancy. This contraindication can be avoid¬ed by performing the examination before the ovulation phase, between the 7th to 10th day of the menstrual cycle. Because of the scattering risk, the examination should be avoided when there is active intrapelvic inflammation. Another contraindication is vaginal or uterine bleeding because of the risk of unrestrained bleeding, which could lead to transfusion or surgical recovery procedures. Fi¬nally, the examination should not be performed in cases of severe cardiac or renal deficiency, or in cases of recent uterine or tubal surgery. Technique Patient Preparation The procedure is performed in the first half of the menstrual cycle following cessation of bleeding. The endometrium is thin during this proliferative phase, which facilitates better image interpretation and should also ensure that there is no pregnancy. The patient is asked to refrain from unprotected sexual intercourse from the date of her period until after the investigation to be certain there is no risk of pregnancy. Examination in the second half of the cycle is avoided because the thickened secretory-phase endometrium increases the risk of venous intravasation and may cause a false-pos¬itive diagnosis of cornual occlusion. Antibiotics might be required 1 day before and for a few days after the examination if previous inflamma¬tions are present in the patient’s clinical history. Antibiotics are required after the examination when the maneuvers are fairly sanguineous or if the fallopian tubes present a certain degree of dilation. The suggest¬ed antibiotic regimen is metronidazole 1 g rectally at the time of the procedure, plus doxycycline 100 mg twice daily for 7 days.Steroid (prednisolone) premed¬ication is prescribed in asthmatics when intravenous contrast is used; there-fore, it is reasonable to do the same for HSG because intravasation is also possible from this procedure. Catheterization Technique For the catheterization technique, the patient is placed on the fluoroscopic machine in a gynecologic examination position. After cleaning the external gen¬ital area with antiseptic solution, the vagina is dilated by a gynecologic dilator. The cervix is localized and cleansed with iodine solution. Afterward, the uterine cervix is straightened by one (at the 12 o’clock posi¬tion) or two (at the 9 and 3 o’clock positions) surgi¬cal forceps exercising a degree of pulling. Next, the outside uterine cervix ostium is catheterized. The catheterization can be performed in two ways. In the authors’ country, a salpinographer with a bell-shaped end (diameter depends on the case) is pushed through the vagina and fits in the external uterine cervix osti¬um. In the second technique, the salpingographer has a plastic cup-shaped end that is fitted to the external uterine cervix ostium, creating a void phenomenon. In both techniques, there is a syringe with iodinated hydrosoluble contrast medium at the other end of the salpingographer. The vagina dilator is taken off after catheterization of the external uteri cervix ostium and before administration of the contrast medium. Contrast Media In the past, oil-soluble contrast media were mainly used. Today, we use all available iodinated hydrosol¬uble contrast media. According to international liter¬ature, the use of oil-soluble contrast media increases the pregnancy rate and contributes to a decrease in conception time after the salpingography is performed. However, Spring and coworkers found that there is no evidence that the choice of the contrast material affects the rate of term pregnancy. Moreover, they reported that oil-soluble contrast media may promote granulo¬matous inflammation in the presence of obstructed or inflamed fallopian tubes. Radiological Views One conventional radiograph of the pelvis (on a 24¬30 cm radiologic film) is necessary before the contrast medium is administrated into the uterine cavity so that possible intrapyelic masses or calcifications will not complicate interpretation of the images. A metallic marker is placed over one side of the pelvis to indicate the right or left side of the patient. Next, the examina¬tion is performed under fluoroscopic control so that ra¬diographs can be taken during the filling of the uterine cavity (usually 2-3 cm of contrast medium is sufficient) and again during the filling of the fallopian tubes. Final¬ly, after the removal of the salpingographer, we radio¬graphically check the presence of contrast medium in the peritoneal cavity. The total amount of injected con¬trast medium should not exceed 10 mL. Additional spot radiographs are obtained to document any abnormality that is seen. Before the first radiograph, we also fluoro- scopically check the reflux of the contrast medium. Complications The two most common complications of HSG are pain and infection. These and other complications and side effects are summarized below. • Uterine contractions and discomfort due to the introduction of contrast medium into the uterine cavi¬ty: The most common type of pain referenced is subab¬dominal colic caused by dilation of the uterine cavity. A more diffuse pain, caused by irritation of the peri¬toneum due to the contrast medium, has also been re¬ported. Pain can be minimized by slowly injecting the contrast medium and using isosmolar contrast agents. • Postprocedural infection: Spreading and gener-alization of intrapyelic inflammation may happen in cases of chronic inflammation and hydrosalpinges, or after severe uterine injury caused by the examination maneuver. • Vasovagal reaction: A possible reaction to ma-nipulation of the cervix or inflation of a conclusion balloon in the cervical canal. • Traumatic elevation of endometrium by the in¬serted cannula: A complication which does not cause significant consequences. • Uterine perforation and tubal rupture: These complications are very rare. • Venous or lymphatic intravasation of contrast me-dia: With a water-based contrast medium there is no ad-verse effect on the patient, but it can make interpretation of the image difficult. It occurs more commonly in the presence of fibroids or tubal obstruction. Extravasation of the contrast medium could occur if the contrast me¬dium is administered too quickly, if the endometrium is injured during the catheterization, or if the examination is performed during menstruation. Extravasation is also possible when common or special inflammations of the endometrium are present due to the intercourse rate be-tween the uterine vein and the ovarian veins. • Allergic reaction to contrast media: Such a reac¬tion is very uncommon with the use of the low-osmolar nonionic contrast agents currently available. • Radiation exposure to the ovaries: Exposure is minimal and can be reduced if the proper technique is utilized. Normal Findings On face radiographs, the uterine cavity has a nor¬mal trigonal shape and the apex of the triangle corre¬sponds to the isthmus, which is nearly 3.7 cm wide. The apex is pointed downwards and connected to the internal ostium of the cervix uteri, which is 2.5 cm in total length. The base of triangular uterine cavity is the fundus, which can be concave, flattened, or slightly convex. On both sides of its base, in the area of the lateral horns, the two fallopian tubes are drowned. The fallopian tubes are separated into three segments: isth¬mus (attached to the uterus, not imaged in several cas¬es), ampullary (in the middle, the longest and widest segment), and bell-shaped (to the distal end). There are two ostiums: the internal or uterine, and the external or abdominal. From the abdominal ostium, the con¬trast medium disperses and diffuses into the peritone¬al cavity. Remaining contrast medium in the furrows of the peritoneum can be observed up to 3 hours after administration. Very often, the contrast medium in the rectouterine pouch of the peritoneum (Douglas’ space) can demonstrate the profile of the coordinate ovary. Congenital Uterus Anomalies Congenital uterus anomalies are caused by incom¬plete junction of the paramesonephric ducts (Muller ducts), or Extravasations of the contrast medium. The true incidence and prevalence of mullerian duct anomalies are difficult to assess. Examination of different patient populations, nonstandardized clas¬sification systems, and differences in diagnostic data acquisition has resulted in widely disparate estimates, with a reported prevalence that ranges from 0.16 to 10%. As a result of selection bias, a prevalence of 8 to 10% has been reported in women being evaluated with HSG because of recurrent pregnancy loss. The overall data suggest that the prevalence both in women with normal fertility and in women with infertility is approximately 1%, and the prevalence in women with repeated pregnancy loss is approximately 3%. While the majority of women with mullerian duct anomalies have little problem conceiving, they have higher associated rates of spontaneous abortion, pre¬mature delivery, and abnormal fetal position and dys¬tocia at delivery. Most studies report an approximate frequency of 25% for associated reproductive prob¬lems, compared with 10% in the general population. Primary infertility in these women usually has an ex¬tra uterine cause and is not generally attributable to mullerian duct anomalies alone. Additionally, cervical incompetence has been reported to be associated with these anomalies. According to the American Society of Reproduc¬tive Medicine, there are seven different classes of mul¬lerian duct anomalies: Class I: Segmental agenesis or variable degrees of uterovaginal hypoplasia. The anomaly can be detected, because of the amenorrhea, before HSG is performed. Class II: Unicornuate uteri that represent partial or complete unilateral hypoplasia. In rare cases of degen-eration of the mesonephric duct, the uterine cavity ap¬pears monocular when imaged, placed right or left of the middle line. The unicornuate uterus contacts only the coordinate fallopian tube. Class III: Didelphys uterus. This is a rare abnor¬mality that results from complete nonfusion of the mullerian ducts, and includes the duplication of the uterine cavity, cervix neck, and vagina. Rarely, this uterus has a single vagina. Class IV: Bicornuate uterus that demonstrates incomplete fusion of the superior segments of the uterovaginal canal. The uterine cavity is divided in two; each half has a narrow-length shape and stands apart from the other. Class V: Septate uteri that represent partial or com¬plete nonresorption of the uterovaginal septum. Class VI: Arcuate uterus resulting from nearly complete resorption of the septum. Along with the pre¬vious anomaly, these are the most common congenital anomalies (50%) in cases detecting female infertility. Class VII: Anomalies that comprise sequelae of in utero diethyloestradiol exposure. Another congenital anomaly, caused by inadequate hormonic stimulation as a fetus, is small uterine cavi¬ty size with normal vaginal length. This is a common finding in cases of female infertility. Abnormal Findings Fibromyomas While fibromas are diagnosed by suprapubic ultra-sound, submucosa fibromyomas are imaged as smooth filling defects in the uterine cavity. Differential diagno¬sis must be made from endometrial polyps or possible pregnancy. Small intramural fibromyomas do not distort the endometrial cavity and are not visualized on HSG. Subserous fibromyomas can provoke smooth filling de-fects or smooth repression of the fallopian tubes only if they are located in the lateral walls of the uterus. Endometrial Polyps Endometrial polyps are focal overgrowths of the endometrium. They usually manifest as well-defined filling defects and are best seen during the early filling stage. Small polyps may be obscured when contrast material completely fills the uterine cavity and may be indistinguishable from a small submucosal myoma. Sonohysterography has become the preferred method of imaging endometrial polyps. Internal Endometriosis (Adenomyosis) Adenomyosis is caused by the presence of ectopic islets of active endometrium in the muscularis wall of the uterus. It is usually imaged as a pointed projection of 2 to 3 mm length, perpendicular to the uterine wall after contrast medium administration. Rarely, this is imaged as a sack-shaped projection filled by contrast medium, 4 mm to 1 cm in length. Differential diag¬nosis should include the hyperplasia of the endome¬trium and the entrance of the contrast medium in the myometrium or in the nutrient arteriole of submucosa fibromyomas. Uterine Cancer Uterine cancer manifests as an irregular filling de¬fect, but is rarely diagnosed by the HSG method. Intrauterine Adhesions Intrauterine adhesions are most commonly caused by endometrial trauma of curettage. They are also seen in patients with chronic endometriosis due to tubercu¬losis. Genital tuberculosis primary affects the fallopian tubes, and 50% of patients with tubal disease also have a uterine abnormality. Intrauterine adhesions manifest as irregular filling defects, most commonly as linear filling defects arising from one of the uterine walls. Hydrosalpinx HSG is the best method for visualizing and eval¬uating the fallopian tubes. Hydrosalpinx is a common finding that results from a previous inflammation of the fallopian tubes (salpingitis). This is usually the se¬quelae of distal tubal occlusion, leading to dilation of the proximal segment. The radiologic image shows a dilated lumen in one or more spots, and the contrast medium will not make its way to the peritoneal cavity Tuberculated Salpingitis This entity usually causes distant fallopian tube end obliteration. In extensive infections, multiple con¬strictions along the course of fallopian tube can form, resulting in areas of dilation and stenosis. Abnormal uterine and vaginal profiles are observed in cases of widespread infection. Salpingitis Isthmica Nodosa Salpingitis isthmica nodosa is a disease of un¬known etiology, characterized by multiple small out- pouchings or diverticula affecting one or both fallopian tubes. It is presumably caused by pelvic inflammatory disease or endometriosis and is associated with ectopic pregnancy and infertility. Nondrawing of the Fallopian Tubes This is the most common finding during the exam-ination and is usually caused by poor technique, spasm, or obliteration of the fallopian tube. Poor technique in¬cludes imperfect straightening of the external cervical ostium or an inadequate amount of contrast medium in the uterine cavity. The cornual portion of the fallopian tube is encased by the smooth muscle of the uterus and, if there is a spasm of the muscle during HSG, one or both tubes may not fill. Using radiography, tubal spasm cannot be distinguished from tubal occlusion. This could be avoided by progressive administration of the contrast medium or, when the spasm occurs, administration of a spasmolytic agent to relieve spasm, helping differentiate cornual spasm from true occlusion. Obliteration is usu¬ally caused by previous inflammation or uterine surgery and manifests as nonopacification or abrupt cutoff of the fallopian tube with no free intraperitoneal spillage. External Adhesions External adhesions occur secondary to previous inflammation or surgery, similar to the causes of tubal occlusion. Peritubal adhesions prevent contrast materi¬al from flowing freely around the bowel loops as seen in normal cases, and most commonly manifest as loc- ulation of the contrast material around the ampullary portion of the tube. Conclusion. HSG remains the front-line imaging modality in the investigation of infertility. It is an ac¬curate means of accessing the uterine cavity and tubal patency, but has a low sensitivity for the diagnosis of pelvic adhe¬sions, which is why it cannot replace laparoscopy. It requires knowledge of the female anatomy as well as skillful technique in order to avoid pitfalls and misin¬terpretations.Кафедра акушерства та гінекологі

Evaluation of endometrial pathologies with high resolution transvaginal ultrasound

Background: The purpose of this study is to evaluate endometrial lesions on the basis of their appearances by high resolution trans-vaginal ultrasound. High resolution trans-vaginal sonography is useful for diagnosis of various endometrial lesions. Broad spectrum of endometrial lesions can be accurately imaged by various available modalities of which ultrasound is easily available, reliable, non-invasive and cost effective modality.Methods: In these study cases with complaints of abnormal uterine bleeding, suspected retained products, white discharge, dysmenorrhea and habitual abortions were evaluated with trans-vaginal ultrasound. Lesions were carefully studied and evaluated. Philips HD-11 and Accuson Siemens ultrasound machines with trans-vaginal probes were used.Results: In all 121 cases, trans-abdominal and trans-vaginal high resolution ultrasound was performed for different lesions in endometrium. Age group of females was between 18 to 65 years. Different uterine lesions were studied. Out of which most commonly encountered lesions were endometrial hyperplasia followed by polyps and least common lesion was AV malformation.Conclusions: High resolution trans-vaginal ultrasound helped in staging and management in cases of ca. endometrium. Hence trans-vaginal ultrasound should be 1st choice of investigation for diagnosis of endometrial lesions

The environment and dry eye—manifestations, mechanisms, and more

Dry eye disease (DED) is a multifactorial condition that often presents with chronic symptoms of pain (that can be characterized as “dryness,” “burning,” and “irritation,” to name a few) and/or fluctuating or poor-quality vision. Given its multifactorial nature, several pathophysiologic mechanisms have been identified that can underlie symptoms, including tear film, ocular surface, and/or corneal somatosensory nerve abnormalities. Research has focused on understanding how environmental exposures can increase the risk for DED flares and negatively impact the tear film, the ocular surface, and/or nerve health. Given that DED is a common condition that negatively impacts physical and mental functioning, managing DED requires multiple strategies. These can include both medical approaches and modulating adverse environmental conditions, the latter of which may be a cost-effective way to avoid DED flares. Thus, an understanding of how environmental exposures relate to disease is important. This Review summarizes research on the relationships between environmental exposures and DED, in the hope that this information will engage healthcare professionals and patients to consider environmental manipulations in their management of DED

Comparison of the safety and efficacy of intracervical Foleys catheter versus PGE2 gel for induction of labour at term

Background: Before the induction of labour cervical ripening is needed for the success of induction to reduce the complication and diminish the rate of cesarean section and duration of labour. Various mechanical methods like Foleys catheter are effective but not much popular because of infection and pharmacological preparations which have more side effects, are used for cervical ripening. Therefore study has been conducted to compare the efficacy and safety of intra cervical Foleys catheter versus PGE2 gel for induction of labour at term. The aims and objectives of this study was to success of induction of labour depends on the cervical status at the time of induction.Methods: A prospective comparative study was conducted in the department of obstetrics and gynecology, L.G. hospital (AMCMET Medical college), Ahmedabad, during period of July 2019 to December 2019. 100 patients at term with a Bishop’s score with various indications for induction were randomly allocated to receive (50 patients) intra cervical Foleys catheter or PGE2 gel (50 patients). Post induction Bishop’s score was noted after 6 hours, 12 hours, 24 hours. Statistical methods used were Student t test and Chi square test to statistically compare the two groups. Differences with a p value of <0.005 was considered statistically significant with confidence limit of 95%.Results: The groups were comparable with respect to maternal age, gestational age, parity, indication of induction and initial bishops score. Both groups showed significant change in the Bishops score, 5.10±1.55 and 5.14±1.60 for Foleys catheter and PGE2 gel, respectively, p<0.001. Fetal outcome was noted in NICU admission and fetal death. No significant difference between two groups.Conclusions: This study shows that both Foleys catheter and PGE2 gel were equally effective in pre induction cervical ripening

Comparative study of efficacy and safety of intravenous ferric carboxy maltose versus iron sucrose in treatment of postpartum iron deficiency anemia

Background: As postpartum iron deficiency anemia is observed in about 65% of women in India, it is the major contributing factor and indirect cause of maternal death. Postpartum anemia may lead to postpartum depression, stress, anxiety and cognitive impairment. Adequate treatment of anemia in postpartum period will have improved life quality in women in child bearing age so this study was designed with the objective to compare the safety and efficacy of intravenous FCM versus iron sucrose in treatment of postpartum iron deficiency anemia.Methods: It was a prospective observational study of postpartum women (within 10 days of delivery) with iron deficiency anemia (7-9 gm%) who delivered in LG hospital, Ahmedabad. A sample size of 215 women was estimated based on prevalence of anemia which is 65% among postpartum women in India including dropout rate of 10% which were further divided into 2 groups. Group 1: iron sucrose group, Group 2: ferric carboxy maltose group.Results: FCM has greater rise in Hb, less side effects, and easy administration of dose as compared to iron sucrose. The rise in Hb with FCM as compared to iron sucrose is (4.6 versus 3.5 respectively).Conclusions: FCM has more safety and efficacy as compared to iron sucrose in treatment of postpartum iron deficiency anemia