Incidence of acute renal failure in birth asphyxia and its correlation with hypoxic-ischemic encephalopathy staging

Introduction: Acute renal failure (ARF) is a recognized complication of birth asphyxia and it carries a poor prognosis. Early recognition of ARF is particularly important in asphyxiated neonates with hypoxic-ischemic encephalopathy (HIE). Objectives: To determine the incidence of ARF in term asphyxiated neonates and to correlate it with HIE staging. Methods: A total of 50 term (37-42 weeks) neonates born with Apgar score of <7 at 5 min after birth were selected as cases and 50 normal term (37-42 weeks) neonates as controls. All asphyxiated neonates with clinical features of HIE are staged by Sarnat and Sarnat staging. Gestational age, birth weight, relevant perinatal history, and examination findings are recorded in predesigned pro forma. After 72 h and before 96 h of life, blood was collected and sent for relevant investigations, and clinical condition of the neonate and urine output were monitored and neonates were managed according to the standard protocol. Results: Incidence of ARF is significantly more in cases (76.0% vs. 4.0%) than the controls. Among 38 cases with ARF, 32 (84.2%) had pre-renal ARF and 6 (15.8%) had intrinsic ARF. On the basis of urine output, 12 (24.0%) had oliguric ARF and 38 cases (76.0%) had non-oliguric ARF while out of 50 controls, 2 (4%) neonates had pre-renal and non-oliguric type of ARF. Incidence of ARF correlated well with HIE staging. Among the 50 cases, 32 (84.3%) improved clinically after fluid therapy, while 6 (15.7%) did not improve. Conclusion: Perinatal asphyxia is an important cause of neonatal renal failure. ARF in birth asphyxia is predominantly pre-renal and non-oliguric type and it responds to fluid challenge. ARF in birth asphyxia correlates well with HIE staging

A case study on deterioration assessment and rehabilitation of fire damaged reinforced concrete structure

Fire is one of the most severe hazards that building structures may experience during their lifetime. A fire spread to the whole structure can cause unexpected damages to the structural elements. Mainly, the building type is crucially important for the type and the level of damage to the building because of the fire. Post fire investigation of damaged structure is required to determine the extent of damage to concrete elements and to work out system of effective repair/rehabilitation measures to maintain the structural integrity of fire effected structural components. The paper covers in brief the strength and durability study on fire damaged building in Delhi, India. The study reports the extent of fire damage. Optical Microscopy (OM), X-Ray Diffraction (XRD) and Deferential Thermal Analysis (DTA) studies were carried out on the sample concrete cores extracted from different identified portions of the fire exposed concrete are highlighted in this paper. Extent of damage occurred in the Reinforced Cement Concrete (RCC) i.e. RCC columns/beams/slabs are described based on the detailed evaluation by various Non-Destructive Evaluation Techniques covering Cover study & Ultrasonic Pulse Velocity (UPV) testing. Repair and remedial measures required for restoration and strengthening of the fire affected RCC columns/beams/slabs using indigenously available repair materials and techniques are also highlighted in this paper

Agroforestry practices for physiological amelioration of salt aff ected soils

Agroforestry is a sustainable land use system act as an alternative form of biological reclamation in salt affected soils apart from sustainable production, continuous income, and regular employment along with food and nutrition security. In general, salt affected soils get ameliorated by tree species; however, following factors such as nature and type of tree species planted, growth habit, quantity and quality of litter production, planting density, nitrogen fixation, and different management practices are influenced. In the present study, various studies pertaining to soil reclamation in the salt affected soils are reviewed. Overall result showed that trees grown with crops, horticultural crops, pastures resulted in improvement of physical and chemical properties of soil under various agroforestry systems. For instance, reduction of soil pH, electrical conductivity, and exchangeable sodium percentage minimization of salt deposition in the upper layers of the soil, improvement of water permeability and water holding capacity, improvement of infiltration rate and hydraulic conductivity with soil fertility, enhancement of cation exchange capacity, and other features are characteristics of soil as influenced by tree species, as well as through agroforestry practices. Various multipurpose tree species such as Acacia auriculiformis, Acacia nilotica, Albizia lebbeck, Terminalia arjuna, Casuarina equisetifolia, Prosopis cineraria, Prosopis juliflora; and fruit trees such as Zizyphus jujuba, Emblica officinalis, Syzygium cumini, and Tamarindus indica ameliorated the different salt affected soils in different agroforestry systems viz., agrisilvicultural system, silvipastoral system, multipurpose wood lot, and agrihorisilvicultural system. Thus, agroforestry system provides an alternative for restoring soil health and amelioration of salt affected soils for further yield improvement. Therefore, these species are suggested for reclamation of salt affected soil through agroforestry systems

Congenital epidermoid cyst of penis with hypospadias: A case report

The epidermoid cysts are the most common cutaneous cysts and may develop from any parts of the human body. Primary epidermoid cyst with hypospadias in the penis is very rare. Here, we present the case of a slow growing, mobilized; non-tender frenulum of the penis mass in a 44-year-old male patient. Complete excision of the cyst was performed under spinal anesthesia. Histopathological examination confirmed the mass to be an epidermoid cyst. Care must be given during examination to rule out another entity. If thereis any indication, complete excision and hypospadias repair is the best treatment

Role of Non-Selective Beta Blockers in Hepatocellular Carcinoma: An Analysis in Patients with Cirrhosis and Portal Hypertension

There are many different biochemical processes responsible for the hepatocelluar carcinoma (HCC) development that can be targeted for the prevention or halt progression of the HCC. Non-selective betablockers (NSBB) affects a multitude of intracellular biochemical and signaling pathways involved in carcinogenesis. Aim: To determine if NSBB may be protective for HCC in patients with cirrhosis and portal hypertension. Methods: We retrospectively enrolled 200 patients from medical records diagnosed with cirrhosis and portal hypertension between January 2001 and December 2013. Eighteen patients were excluded (taking selective beta-blocker and/or unavailable medical records). The etiology of cirrhosis, use of NSBB, demographics and the presence of HCC was collected. Result: There were 140 males and 42 females. The mean age for portal hypertension with cirrhosis without HCC was 53.5 ± 11.4 & with HCC was 62.2 ± 9.5 years. Univariate analysis of the association of NSBB with HCC yielded OR = 0. 11 (95% CI: 0.04 to 0.25); p \u3c 0.0001, suggesting a protective effect of NSBB. Multivariable analysis suggests virtually no change when the Odds ratio (OR) was adjusted for diabetes mellitus (DM), alcohol use, Hepatitis B virus (HBV) status, Black race and age ≥ 53. There was a slight increase in the OR adjusted for statin use. Conclusion: This study highlights association of NSBB use in the patients with liver cirrhosis and portal hypertension for prevention of HCC

High yield synthesis of electrolyte heating assisted electrochemically exfoliated graphene for electromagnetic interference shielding applications

Herein, we demonstrate a facile one pot synthesis of graphene nanosheets by electrochemical exfoliation of graphite. In the present study, we report a significant increase in the yield of graphene by electrolyte heating assisted electrochemical exfoliation method. The obtained results of heating assisted electrochemically exfoliated graphene (utilizing H2SO4 + KOH + DW) synthesis clearly exhibit that the yield increases similar to 4.5 times i.e. from similar to 17% (room temperature) to similar to 77% (at 80 degrees C). A plausible mechanism for the enhanced yield based on lattice expansion and vibration of intercalated ions has been put forward and discussed in details. The quality of graphene was examined by Raman, XPS, FTIR, AFM, SEM, TEM/HRTEM and TGA techniques. The Raman as well as morphogenesis results confirm the quality of the graphene nanosheets. We have used this graphene as electromagnetic interference shielding material where a comparatively large quantity of graphene is required. This graphene exhibits enhanced shielding effectiveness (46 dB at 1 mm thickness of stacked graphene sheets in frequency region 12.4 to 18 GHz) as compared to conventional electromagnetic interference shielding materials, which is greater than the recommended limit (similar to 30 dB) for techno-commercial applications. Thus the present work is suggestive for future studies on enhancement of yield of high quality graphene by proposed method and the use of synthesized graphene in electromagnetic interference shielding and other possible applications

Electro-catalyzed cynoarylmethylation of isatin for synthesis of 3-hydroxy-3-cynomethyl oxindole derivatives

An efficient and economical method has been developed for synthesis of 3-substituted oxindole by using electrochemically induced condensation of various N-substituted isatin, phenyl acetonitrile

Groundwater hydrochemistry of Rajnandgaon district, Chhattisgarh, Central India

The spreading of fluorosis diseases in Central India related to high concentrations of fluoride ion (F−) is a cause of major concern. In this work, the hydrochemistry of the aquifers related to Seonath River, in Rajnandgaon district, Chhattisgarh state, India, has been studied, focusing on the presence and sources of F−. Hydrochemical parameters were analyzed in the post-monsoon season in 160 wells located in nine tehsils, finding F− concentrations ranging from 0.6 to 18.5 mg L−1. Seasonal variations were also studied in Chhuikhadan tehsil, in which the highest F− values were registered, finding a noticeable enrichment in the pre-monsoon months. In many locations of the district, F− concentrations exceeded the recommended value of 1.5 mg L−1, which have led to the appearance of several health issues. Multidimensional analysis statistical methods were adopted to investigate the sources of F−, and the mineralization of bedrock elements into the groundwater was observed to be the primary source