5 research outputs found
Geochemical study of the early cretaceous Fahliyan oil reservoir in the northwest Persian Gulf
Three crude oil samples from the Fahliyan Formation in ‘KG’ and ‘F’ fields in the northwest Persian Gulf, namely KG-031, F9A-3H and F15-3H for the geochemical study. In this study, the physicochemical properties, gas chromatography (GC, GC Mass) and (Detailed Hydrocarbon Analysis) DHA analyses for the collected Fahliyan oils were carried out. The API, Trace Element (Ni, V) and S% parameters indicated that the Fahliyan oil was generated from a source rock which deposited in reducing environment condition with a carbonate-shale compound lithology. Moreover, low pour point, higher S% and low viscosity parameters of “KG” sample confirmed the existence of medium oil characteristics in this field. In addition, the geochemical outcomes of GC, GC–MS and DHA analyses indicated that the ‘KG’ oils are more aromatic compared with ‘F’ oil; while biomarkers revealed that Fahliyan reservoir oil is highly mature and was formed from a carbonate source rock containing types II, III kerogen. Thus, sterane/hopane biomarkers (C24/C23 and C22/C21 ratios) revealed that Fahliyan oil originated from carbonate source rocks deposited in an anoxic to dysoxic environment, which is consistent with the above analyses. It was identified that the source rock age is early Cretaceous to late Jurassic. It can be reported that the Fahliyan oils from both fields were generated in the same source rock and have almost the same physical properties, and will have the same production strategy
Radioprotective effect of Malva sylvestris L. against radiation-induced liver, kidney and intestine damages in rat: A histopathological study
Background: Ionizing radiation (IR) is widely used in the treatment of cancer in radiotherapy. One of the main concerns of patients with gastrointestinal cancers undergoing radiotherapy is the harmful side effects of IR on normal tissues. The liver, kidney, and duodenum are usually exposed to high doses of radiation in the treatment of some cancers in abdominal region radiotherapy. We aimed to assess the radioprotective effects of Malva sylvestris L. against IR damages to the abdominal region. Materials and methods: This current study was conducted on 45 rats divided randomly into nine groups of five: A) negative control group, B) sham group, C) irradiation group, D) mallow treatment-1(200gr/kg), E) mallow treatment-2(400gr/kg), F) mallow treatment-3(600gr/kg), G) mallow treatment-4(200gr/kg) plus irradiation, H) mallow treatment-5(400gr/kg) plus irradiation, I) mallow treatment-6(600gr/kg) plus irradiation. Irradiation was performed with a 6Gy x-ray. Histopathological evaluations were performed 10 days after irradiation. Results: The histopathological examination results confirmed that preventive therapy with the effective dose of mallow reduced the liver, kidney, and intestine damage induced by radiation. The dose of 400 mg/kg was more effective than other selected dose in improving the damage caused by irradiation in the studied tissues. Conclusion: This study concludes that Malva sylvestris L. contributed to significant improvements in radiation-induced histological parameters of the liver and kidney and, to a lesser extent, in the intestine. These results collectively indicate that mallow is an effective radioprotective agent
Pathologic Characteristics and Treatment Outcome of Patients with Malignant Brain Tumors: A Single Institutional Experience from Iran
Background: Central nervous system tumors account for 2%-5% of all
malignancies in humans. These tumors account for 2% of all pediatric cancers. The
worldwide incidence of primary central nervous system tumors is estimated at 3.9
(males) and 3.2 (females) per 100000 person-years. The incidence of brain tumor cases
has been reported as 3.67% of all malignancies and 4% of all cancer mortalities in
Iran. The five most common histological types of brain tumor in Iran according to
different case studies are; meningioma, astrocytoma, glioblastoma, pituitary adenoma
and ependymoma. The aim of this study is to determine the histopathological pattern
and characteristics of patients with brain tumors who have referred to the Mahdieh
Radiotherapy Department, Hamadan, Iran.
Methods: This descriptive, retrospective study was performed at the Mahdieh
Radiotherapy Department, between 2005 and 2012. We included 220 patients who
referred to the Radiotherapy Department with diagnoses of primary brain tumor in
this study.
Results: Between 2005 and 2012, we treated 220 new cases of primary brain tumor
at Mahdieh Radiotherapy Department. The mean age at diagnosis was 39.95±15.48
years with a median age of 39 years. Patients' ages ranged from 4 to 75 years.
Among the 220 patients, 138 were male and 82 were female with a male to female
ratio of 1.68. For most tumors there was a male predominance, with the exception
of meningioma (M/F: 0.23), ependymoma (M/F: 1) and pituitary adenoma (M/F: 0.6).
Astrocytomas, glioblastomas, high grade meningiomas and oligodendrogliomas
were the four most common pathologies treated in this department. The best treatment
results were achieved in patients with astrocytomas.
Conclusion: The present study is a retrospective radiotherapy centre-based study
designed in a pioneer radiotherapy centre in Western Iran, not a prospective population
study. These data have provided a baseline for further epidemiological studies. Our
encouraging results in radiotherapy treatment of primary malignant tumors clearly
highlight the benefits of definitive or postoperative radiation