KIC 3440495: A Rapidly Rotating δ Scuti-γ Doradus Hybrid Pulsator in a Binary System

In this paper, we study the pulsation properties of KIC 3440495 using Kepler and TESS data. A Fourier analysis of the light curve reveals 24 pulsation modes as well as 29 frequencies associated with rotation. The rotation frequency is derived to be frot = 2.322909(2) day−1, and the rotational modulation is determined to be caused by starspots. A large frequency separation of Δν = 54.5 μHz is found by using a Fourier transform, the autocorrelation function, a histogram of frequency differences, and an échelle diagram. We use the large separation to estimate the refined stellar parameters of the star to be v = [239, 279] km s−1, M= [1.5, 1.65] Me, Requator = [2.03, 2.30] Re, Rpolar = [1.72, 1.78] Re, and ω = [0.61, 0.77]. The phase modulations of the pulsating frequencies show a long-term trend which may be attributed to an orbital effect of a binary system; hence, the star may be a fast rotating pulsator in a binary system. KIC 3440495 has an amplitude spectrum similar to Altair, and is identified as a potential sister of Altair. Based on studies of Altair, KIC 3330495 is presumably a young star at a similar evolutionary stage.National Natural Science Foundation of China (NSFC) 12003060 U2031209Natural Science Foundation of Xinjiang Uygur Autonomous Region 2020D01B59Chinese Academy of Sciences (CAS) "Light of West China" Program 2021-XBQNXZ-029"FEDER/Junta de Andalucia-Consejeria de Economia y Conocimiento" by Universidad de Granada E-FQM-041-UGR18"Programas Estatales de Generacion de Conocimiento y Fortalecimiento Cientifico y Tecnologico del Sistema de I+D+i y de I+D+i Orientada a los Retos de la Sociedad" from the Spanish Ministry of Science, Innovation and Universities (MCIU) PID2019-107061GB-C63State Agency for Research through the "Center of Excellence Severo Ochoa" award from the Spanish Ministry of Science, Innovation and Universities (MCIU) SEV-2017-070

Calidad de prescripción de montelukast en pacientes adultos: Estudio en tres farmacias comunitarias de la Comunidad Valenciana

Introducción: El objetivo de este trabajo es analizar la utilización de montelukast en adultos desde tres farmacias comunitarias.Material y métodos: Estudio descriptivo, observacional en tres farmacias comunitarias (enero 2009 - febrero 2013) en pacientes mayores de 15 años que acuden a la farmacia con receta de montelukast. Los datos se recogen a través de encuesta (edad, patología, régimen terapéutico, duración del tratamiento, medicación asociada) y se valora la idoneidad de la prescripción según las indicaciones autorizadas y su adecuación a las guías de práctica clínica. Se remitió al médico, cuando se detectó un tratamiento inadecuado para la revisión del mismo.Resultados: Se incluyen un total de 106 pacientes, de los cuales, el 26 % no padece asma y están tomando montelukast fuera de indicación. De los asmáticos, el 29 % de los tratamientos pautados no se ajusta a las recomendaciones de las guías. Destaca tanto la elevada instauración de montelukast como tratamiento de inicio (59 % asmáticos, 63 % no asmáticos), como el empleo de montelukast en monoterapia (16 % asmáticos, 41 % no asmáticos).Conclusiones: Se está haciendo un uso fuera de indicación de montelukast en pacientes no asmáticos con rinitis alérgica o bronquitis que podría derivar de la falta de claridad en las indicaciones de algunas guías. Además, en pacientes asmáticos, no siempre se está utilizando montelukast según las recomendaciones de las guías clínicas, lo que evidencia la necesidad de información clara a los profesionales sanitarios sobre el papel de montelukast en la terapéutica actual

V2A-Mapper: A Lightweight Solution for Vision-to-Audio Generation by Connecting Foundation Models

Building artificial intelligence (AI) systems on top of a set of foundation models (FMs) is becoming a new paradigm in AI research. Their representative and generative abilities learnt from vast amounts of data can be easily adapted and transferred to a wide range of downstream tasks without extra training from scratch. However, leveraging FMs in cross-modal generation remains under-researched when audio modality is involved. On the other hand, automatically generating semantically-relevant sound from visual input is an important problem in cross-modal generation studies. To solve this vision-to-audio (V2A) generation problem, existing methods tend to design and build complex systems from scratch using modestly sized datasets. In this paper, we propose a lightweight solution to this problem by leveraging foundation models, specifically CLIP, CLAP, and AudioLDM. We first investigate the domain gap between the latent space of the visual CLIP and the auditory CLAP models. Then we propose a simple yet effective mapper mechanism (V2A-Mapper) to bridge the domain gap by translating the visual input between CLIP and CLAP spaces. Conditioned on the translated CLAP embedding, pretrained audio generative FM AudioLDM is adopted to produce high-fidelity and visually-aligned sound. Compared to previous approaches, our method only requires a quick training of the V2A-Mapper. We further analyze and conduct extensive experiments on the choice of the V2A-Mapper and show that a generative mapper is better at fidelity and variability (FD) while a regression mapper is slightly better at relevance (CS). Both objective and subjective evaluation on two V2A datasets demonstrate the superiority of our proposed method compared to current state-of-the-art approaches - trained with 86% fewer parameters but achieving 53% and 19% improvement in FD and CS, respectively.Comment: 13 pages, 10 figures. Demo page: https://v2a-mapper.github.io

Montera: A Framework for Efficient Execution of Monte Carlo Codes on Grid Infrastructures

he objective of this work is to improve the performance of Monte Carlo codes on Grid production infrastructures. To do so, the codes and the grid sites are characterized with simple parameters to model their behaviors. Then, a new performance model for grid infrastructures is proposed, and an algorithm that employs this information is described. This algorithm dynamically calculates the number and size of tasks to execute on each site to maximize the performance and reduce makespan. Finally, a newly developed framework called Montera is presented. Montera deals with the execution of Monte Carlo codes in an unattended way, isolating the complexity of the problem from the final user. By employing two fusion Monte Carlo codes as example cases, along with the described characterizations and scheduling algorithm, a performance improvement up to 650 % over current best results is obtained on a real production infrastructure, together with enhanced stability and robustness

COMMUNICATED PARENTING: SINGAPORE-BASED FILIPINO WORKING MOTHERS AND THEIR LONG-DISTANCE PARENTING OF THEIR TEENAGE CHILDREN IN THE PHILIPPINES

Master'sMASTER OF ART

Diastereoselective insertion of isocyanide into the alkyl metal bond of methylbenz[e]indenyl ansa-zirconocene complexes

Alkylation of ansa-zirconocene [Zr{(η5-C5H5)SiMe2(MBI)}Cl2] (MBI = η5-2-Me−C13H7) with MgRCl gave the dimethyl complex [Zr{(η5-C5H5)SiMe2(MBI)}Me2], but unresolvable mixtures containing mono-alkylated compounds were obtained when bulkier alkyls were used. However pure dialkyl complexes [Zr{(η5-C5H5)SiMe2(MBI)}R2] (R = CH2Ph, CH2SiMe3) were easily obtained using K(CH2Ph) and Li(CH2SiMe3) as alkylating agents. Diastereoselective insertion into the MBI-unprotected Zr−R bond was observed when all of these dialkyl complexes were treated with 2,6-xylyl isocyanide to give the iminoacyl compounds [Zr{(η5-C5H5)SiMe2(MBI)}R{CR[η2-N-(2,6-xylyl)]}] (R = Me, CH2Ph, CH2SiMe3). All of the new complexes were characterized by NMR spectroscopy and the X-ray molecular structures of the dibenzyl and the imino-benzyl compounds were determined. The catalytic activity for ethene polymerization and ethene/1-hexene copolymerization of the dichloro zirconocenes [Zr{(η5-C5H5)EMe2(MBI)}Cl2] (E = C, Si), activated with methylalumoxane (MAO), was measured.Repsol-YP

Monopentamethylcyclopentadienyl isocyanide, amine and imido tantalum(V) complexes. X-ray crystal structure of [TaCp*Cl4(CN-2,6-Me2C6H3)]

[TaCp★Cl4](Cp★ = η5-C5Me5) reacts with isocyanides and amines to give the pseudo-octahedral adducts [TaCp★Cl4L] (L = 2,6-Me2C6H3NC, 1; 2,4,6-Me3C6H2NC, 2; tBuNC, 3; or C6H5NH2, 4). Reduction of 1, or alternatively of [TaCp★Cl4] in the presence of stoichiometric amounts of isocyanide, with two equivalents of Na/Hg gives the diamagnetic pseudo-octahedral tantalum(III) complex, [TaCp★Cl2(CN-2,6-Me2C6H3)35. Reaction of 4 with two equivalents of LiNEt2 affords the pseudo-octahedral imido complex [TaCp★Cl2(NC6H5). 6. All the complexes were characterized by usual IR and NMR spectroscopic methods and the molecular structure of I was confirmed by X-ray diffraction methods

Allylsilylcyclopentadienyl Group 4 metal complexes: synthesis, structure and reactivity

(Allyldimethyl)silyl-substituted cyclopentadiene C5H5SiMe2(CH2CH /CH2) (1) and indene C9H7 /1-SiMe2(CH2CH /CH2) (2)\ud were synthesized by reaction of SiMe2(CH2CH /CH2)Cl with NaC5H5 or LiC9H7, respectively. Metallation of 1 with n-BuLi and\ud TlOEt gave the corresponding lithium 3 and thallium 5 salts. The disilylcylopentadienes C5H4 /1-SiMe3 /1-SiMe2(CH2CH /CH2) (6)\ud and C5H4 /1,1-[SiMe2(CH2CH /CH2)]2 (7) were prepared by reaction of 3 with the corresponding chlorosilanes. Compound 7\ud reacted with TiCl4 to give the monocyclopentadienyl compound [Ti{h5\ud -C5H4SiMe2(CH2CH /CH2)}Cl3] (8), while 5 was used to\ud prepare the titanocenes [Ti(h5\ud -Cp){h5\ud -C5H4SiMe2(CH2CH /CH2)}Cl2] (Cp /C5H4SiMe2(CH2CH /CH2) 9, C5H5 10, C5Me5 11) by\ud reaction with the appropriate TiCpCl3 derivative. The related dicyclopentadienyl [Zr{h5\ud -C5H4SiMe2(CH2CH /CH2)}2Cl2] (12),\ud [Zr(h5\ud -C5H5){h5\ud -C5H4SiMe2(CH2CH /CH2)}Cl2] (13), and indenyl [Zr(h5\ud -C5H5){h5\ud -C9H6SiMe2(CH2CH /CH2)}Cl2] (14) zirconium\ud derivatives were isolated by reaction of ZrCl4 and Zr(h5\ud -C5H5)Cl3 /DME with the lithium salts 3 and 4, respectively.\ud Alkylation of the metallocene complexes using MeLi, MgMeCl, Mg(CH2Ph)Cl and Mg(CH2Ph)2(THF)2 afforded the monomethyl\ud titanium [Ti(h5\ud -C5H5){h5\ud -C5H4SiMe2(CH2CH /CH2)}ClMe] (15) and the dialkyl cyclopentadienyl [M(h5\ud -C5H5){h5\ud -C5H4SiMe2\ud (CH2CH /CH2)}R2] (R /Me, M /Ti 16, Zr 18; R /CH2Ph, M /Ti 20, Zr 22), [Zr{h5\ud -C5H4SiMe2(CH2CH /CH2)}2R2] (R /Me\ud 17, CH2Ph 21) and indenyl derivatives [Zr(h5\ud -C5H5){h5\ud -C9H6SiMe2(CH2CH /CH2)}R2] (R /Me 19, CH2Ph 23). The molecular\ud structure of 11 was studied by X-ray diffraction methods. The reactions of the dialkyl derivatives with B(C6F5)3 were monitored by\ud NMR spectroscopy at variable temperature. The catalytic activity of the dichloro zirconium complexes in the presence of\ud methylalumoxane (MAO) for ethylene polymerization was determined.Financial support of our work by MCyT (Project\ud MAT2001-1309) is gratefully acknowledged. G.H., G.M\ud and J.C are grateful to to the Alexander von HumboldtStiftung,\ud MEC and CAM for fellowships