The evaluation between vitamin D level and pelvic organ prolapse in post-menopausal women

Background: Vitamin D is important for skeletal integrity and optimal muscle function. The high incidence and prevalence of vitamin D deficiency and pelvic organ prolapse have been found in postmenopausal women, raising the question of whether the entities are related. The aim of the study was to evaluation between vitamin D level and pelvic organ prolapse in post-menopausal women. Methods: This case control study has been designed and conducted in the Department of Obstetrics and Gynecology, BSMMU to investigate the level of vitamin D in patients with and without pelvic organ prolapse to explore the association of vitamin D with pelvic organ prolapse. After taking informed written consent the serum vitamin D level of all participants was measured by CMIA technology with flexible assay protocols at Biochemistry and Molecular Biology department of the same institute. Statistical analysis of the results was obtained by using window-based computer software devised with Statistical Packages for Social Sciences (SPSS-24). Results: The study population was divided into two groups, a case group (n=74) consisting of patients with pelvic organ prolapse and a control group (n=74) comprising of women without pelvic organ prolapse. A total 148 participants of 52 years or older attending the out or inpatient department were enrolled in the study. Mean±SD level of Vitamin D in the case group was 13.96±5.18 ng/ml and in the control, group was 21.08±5.77 ng/ml respectively. The difference was statistically significant (p<0.05). Moreover, the vitamin D levels were inversely proportionate with the severity of pelvic organ prolapse. Conclusions: Vitamin D deficiency may be an important systemic factor associated with pelvic organ prolapse. Measuring vitamin D levels in postmenopausal women and replenishing deficiencies may also be important for the pelvic floor

Review of the adaptive re-use of three colonial buildings in Dhaka, Bangladesh

Adaptive reuse is a process of redevelopment and regeneration of historic building that can be reuse for new purposes which provides social, environmental and economic benefits. Bangladesh have experienced long colonial past (1757 to 1947). During colonial period developed many significant buildings with colonial style and character. These buildings had strong impact on society, culture and history. However, many of these colonial buildings are not conserving and well documented for future generation. As a result, several colonial buildings are gradually decaying and abandonedor used by illegal people. Very few buildings are conserving and reusing by the government however, most of these buildings are in critical condition. In this study, we evaluated the current situations of conservation and adaptive reuse of three British colonial buildings (Ahsan Monzil, Curzon Hall and Ruplal House) in Dhaka, Bangladesh. To get the optimum result, three British colonial buildings selected as sample and qualitative methods applied for study. Interview, documents study and observation are the three main techniques for qualitative method, which applied for data collection. In order to identify the challenges or problems between the conservation practice and current condition of adaptive reuse, have analyzed in existing framework or guide lines that provided by the government of Bangladesh and international conservation principles, which delivered by the UNESCO, ICOMOS, ICCOROM and international Charters. Based on the data collections have revealed multiple causes, which severely effects to the longevity and adaptive reuse of British colonial buildings, such as: lack of proper planning and guidelines by the government, insufficient fund, lack of expert technical people, ignorance of implementation, weaken of monitoring system and lack of people’s awareness. In such a deplorable condition, it is essential to reform the government framework, which followed by the international guidelines that provided by the international organizations and at the same time can full fill the all aspects and needs of Bangladesh’s colonial buildings adaptive reuse. If the government and related authorities initiates these types of actions, the people will get multiple benefits from adaptive reuse of colonial buildings, such as economic, social, cultural, job opportunity, recreational, environmental and logical connection with the past and future generation

Protective effect of tomato against adrenaline-induced myocardial infarction in rats

Lycopene, a carotenoid rich in tomato fruit (ripe), is an effective antioxidant and free radical scavenger. In this study n-hexane extract of tomato was evaluated for its protective action against oxidative stress in experimental myocardial infarction induced by administration of adrenaline in rats. Adrenaline produced significant elevation of malondialdehyde content of heart, an indicator of lipid peroxidation, with a significant rise in serum aspartate aminotransferase (AST) level and different grades of necrotic changes in myocardium. Rats were treated with two doses of n-hexane extract of tomato, intragastrically daily for one month prior to administration of adrenaline on the 31 st and 32 nd day. Pretreatment of tomato extract (1 mg/kg, 2 mg/kg) and vitamin E (50 mg/kg) significantly reduced the malondialdehyde concentration in heart and significantly lowered the serum AST level in adrenaline treated rats. Myocardial necrosis was significantly prevented by pretreatment. These results suggest that n-hexane extract of tomato possesses antioxidative property that may protect heart against catecholamine induced myocardial infarction

Consumer evaluation of beautification products: Effects of Extrinsic cues

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