NURTURING 21ST CENTURY SKILLS THROUGH SERVICE LEARNING: FROM ISOLATION TO CONNECTION

As our nation is gearing up towards 21 century learning, herculean measures have been taken to ensure that our students are geared with 21st century skills. One of the key milestone in tailoring our students with 21st century skills is Service Learning (SL). Although SL is incorporated in the education world, the advent of Service Learning concept itself is still relatively new in our region. This quasi-experimental study explored on the effects of service learning on student’s attitude towards learning. The pre and post-survey data shows that service learning has significant positive impact on student’s learning attitude (Mean=10.2, SD=1.74). Concomitantly, service learning has a bright prospect in our country towards honing 21st century skills among our students

Transport Theory of Massless Fields

Using the Schwinger-Keldysh technique we discuss how to derive the transport equations for the system of massless quantum fields. We analyse the scalar field models with quartic and cubic interaction terms. In the $\phi^4$ model the massive quasiparticles appear due to the self-interaction of massless bare fields. Therefore, the derivation of the transport equations strongly resembles that one of the massive fields, but the subset of diagrams which provide the quasiparticle mass has to be resummed. The kinetic equation for the finite width quasiparticles is found, where, except the mean-field and collision terms, there are terms which are absent in the standard Boltzmann equation. The structure of these terms is discussed. In the massless $\phi^3$ model the massive quasiparticles do not emerge and presumably there is no transport theory corresponding to this model. It is not surprising since the $\phi^3$ model is anyhow ill defined.Comment: 32 pages, no macro

Strategies to inhibit tumour associated integrin receptors: rationale for dual and multi-antagonists

YesThe integrins are a family of 24 heterodimeric transmembrane cell surface receptors. Involvement in cell attachment to the extracellular matrix, motility, and proliferation identifies integrins as therapeutic targets in cancer and associated conditions; thrombosis, angiogenesis and osteoporosis. The most reported strategy for drug development is synthesis of an agent that is highly selective for a single integrin receptor. However, the ability of cancer cells to change their integrin repertoire in response to drug treatment renders this approach vulnerable to the development of resistance and paradoxical promotion of tumor growth. Here, we review progress towards development of antagonists targeting two or more members of the RGD-binding integrins, notably αvβ3, αvβ5, αvβ6, αvβ8, α5β1, and αIIbβ3, as anticancer therapeutics

The effect of two training protocols, resistance and High Intensity Interval Training on PPAR-y gene expression in visceral fat tissue in obese diabetic

Documentos apresentados no âmbito do reconhecimento de graus e diplomas estrangeirosAbstract Introduction: Obesity and type 2 diabetes are the leading causes of death and disability adjusted life years in the world. On the other hand, exercise and physical activity are considered as a safe and cost-effective way to prevent and control type 2 diabetes and obesity. However, researchers are still looking at the effects of exercise on the factors that affect these diseases. Therefore, the aim of the present study was to investigate the effect of two training protocols, resistance and High Intensity Interval Training on PPAR-y gene expression in visceral fat tissue in obese diabetic rats. Methods: Statistical samples of the present study were male Wistar rats of Pasteur Institute of Tehran. 18 male 10-week-old male Wistar rats weighing 220±20 g were divided into three obese diabetic groups (control, resistance training group and high-intensity interval training). Finally, the samples were divided into three groups: resistance training (6 heads), control (6 heads) and high intensity interval training (6 heads). In addition to the high-fat diet, the resistance training group performed resistance training for 6 weeks, 5 sessions per week in 5 sets with 4 repetitions in each set. Further, in addition to the high-fat diet, the high-intensity interval training group performed high-intensity interval aerobic exercise for 6 weeks, 5 sessions of 30 minutes. The control group only continued the normal course of their lives with a high-fat diet. Finally, all rats were dissected 48 hours after the last training session and serum indices and visceral adipose tissue gene expression were measured. For statistical analysis, SPSS software version 25 and repeated measures ANOVA were used. Results: The results of statistical analysis of the data showed a significant increase in the expression of PPAR-y gene (p <0.05), serum insulin (p <0.01) and a significant decrease in serum glucose (p <0.01) and insulin resistance (p <0.01). 0.01) in the HIIT exercise group. Also, serum insulin levels in the resistance training group were significantly increased (P, 0.01) and serum glucose levels (p <0.01) and insulin resistance (p <0.01) were significantly reduced. Conclusion: In general, according to the results of the present study on improving glucose indices such as decreased serum glucose and insulin resistance and increased serum insulin levels in the two groups of resistance training and HIIT and also a significant increase in PPAR y gene expression in the HIIT group, these protocols can be used to control and prevent type 2 diabetes, as well as, managing its complications, including obesity

Good Women, Martyrs, and Survivors A Theoretical Framework for South Asian Women's Responses to Partner Violence

25 page(s

Unmaking the good woman

Bibliography: pages 526-546.1. Introduction -- 2. Theoretical literature review -- Empirical background: the Asian literature -- Theoretical background -- Three models: relevance of basic assumptions, usage and cultural compatibility -- Giving voice to women's responses: clinical evidence, issues and themes -- 3. Empirical literature review -- Partner violence -- Coping -- Social support -- 4. Methodology -- 5. Quantitative results -- Psychometric assessment of the developed questionnaires -- Scale development: factor analysis -- The three factor solution -- Reliability analysis of ways of coping - Sri Lanka WOCSL Scale -- Support Systems questionnaire -- Reliability analysis of the Support System Scale -- Partner violence questionnaire -- Validity measures for the developed instruments -- Quantitative analysis of the results -- Correlation coefficient analysis -- Cluster analysis -- One-way analysis of variance (ANOVA) -- 6. Qualitative results -- A theory on the process of women's resilience development and recovery in responding to PV -- The phenomenon of partner violence in Sri Lanka: dynamics of PV, socio-cultural factors and help-seeking -- Characteristics of partner violence -- Perpetrator characteristics -- Dynamics of culture and the socialization process -- Emotional factors related to PV and help-seeking -- 7. Qualitative results -- A theory on the process of women's resilience development and recovery in responding to partner violence -- Stage 1 - Victimization: "I'm trying, but it's not working: I need to please others and stay" -- Stage 2 - Active exploratory coping: "It's not working, so let's try different, more active methods" -- 8. Qualitative results -- Stage 3 - Targeted coping: "I am becoming resilient: I matter, I decide what I need" -- Stage 4 - Transformative stage: "That's it - I have tried everything, now I am ending this" -- Stage 5 - Resilience and recovery stage: "I have arrived and found myself, now it is about me as well as others" -- 9. Discussion -- The process of resilience development and recovery in responding to partner violence -- Coping as a process -- The process of cognitive development -- Support-seeking and support-giving as a process -- Moments of insight (MOIs) as a possible mechanism for the resilience development process -- Women's development of agency as a process -- Partner violence and perpetrator characteristics -- The culture and the socialization process -- Issues relating to children -- Comparison of the emergent theory with the tentative model -- Development of culturally relevant questionnaires.Women's agency in resolving partner violence (PV) is well documented. However, empirical, theoretical, and clinical understandings of PV in South Asia in general, and Sri Lanka in particular, are limited. This is the first in-depth investigation into women's help-seeking, coping, and social support in the context of PV in Sri Lanka. Its primary aim is to examine women's coping strategies and support systems in ending violence, whilst developing a theory for women's responses to PV. Insofar as it links these variables in a single study, and attempts to develop a theory of resilience in the face of PV, this investigation is also the first of its kind for South Asia. Women's process of responding to PV is examined using a representative sample of types of PV, relationships, PV experiences, help-seeking, and socio-demographics. -- Eighty-four participants accessing crisis centres and hospital desks were selected. The mixed methods design included questionnaires and interviews. For analysis, qualitative grounded theory was employed, backed by quantitative analysis of the constructs examined. -- The main contribution is a theory developed to explain the process of women's responses to PV. The theory encapsulates the process of resilience development and recovery in responding to PV. It demonstrates that responses to violence occur as a non-linear, five-stage process, with regressions in most stages. The theory posits that critical incidents and turning points facilitate moments of insight leading to insight-mediated personality changes and to progression through the stages. It also demonstrates that participants employ increased resilience to transform themselves, the PV, and the culture they occupy. The theory also demonstrates that coping, support seeking and support giving occur as non-linear processes, whilst cognitive development and women's development of agency occur as linear processes. The findings support the study's hypotheses by demonstrating that various coping strategies (problem and emotion focused) and support systems (informal and formal) are necessary for ending PV. The study identified the critical roles of socio-cultural factors as obstacles, and children as essential support givers, for women's agency in ending PV. Besides contributing theoretically and empirically to several research domains, this study also addresses serviceprovision needs of help-seeking women.Mode of access: World Wide Web.1 online resource (xvi, 546 pages

Informed consent: Consent by signature or information?

Obtaining informed consent is an ethical requirement for respecting the autonomy of the patient. However, assumptions concerning the patient’s capacity to understand the explanation and its risks sometimes lead to a situation in which the patient signs consent form without a true understanding of the possible complications and ramifications of the procedure. Sufficient time must be allocated to assure that the patient has a full understanding of the risks and benefits and that the patient’s questions have been answered before he or she signs the consent form

El papel del ejercicio y la actividad física en las enfermedades relacionadas con el envejecimiento y los síndromes geriátricos

Aging is a complex process of physiological and social changes that leads to various diseases. The number of elderly people in the world is increasing dramatically and it should be noted that rapid population aging represents a major public health burden. On the other hand, providing an appropriate and low-cost approach to control and prevent complications such as chronic diseases, physical dysfunction, and the geriatric syndrome is necessary. Also, numerous studies have shown that participation in physical activity and exercise training reduces the incidence of dysfunctional capacity, cardiovascular and metabolic disease, as well as the premature death rate in older adults. After plenty of precise observations about the role of exercise on aging-related diseases and geriatric syndromes articles, the benefits of exercise and physical activity in older adults will be more tangible. Therefore, thefirst purpose of the present review was to investigate the mechanisms of PA and exercises that are involved in the prevention of aging-related diseases and GS using current evidence (from 2015 onwards). Also, thepurpose of this study was to provide an exercise guideline (aerobic and resistance training) based on recent evidence (from 2015 onwards).El envejecimiento es un proceso complejo de cambios fisiológicos y sociales que conduce a diversas enfermedades.El número de personas de edad avanzada en el mundo está aumentando drásticamente y cabe señalar que el rápido envejecimiento de la población representa una importante carga para la salud pública.Por otro lado, es necesario brindar un enfoque adecuado y de bajo costo para controlar y prevenir complicaciones como enfermedades crónicas, disfunción física y síndrome geriátrico.Además, numerosos estudios han demostrado que la participación en la actividad física y el entrenamiento físico reduce la incidencia de disfunciones, enfermedades cardiovasculares y metabólicas, así como la tasa de muerte prematura en los adultos mayores.Después de muchas observaciones precisas sobre elpapel del ejercicio en los artículos sobre enfermedades relacionadas con el envejecimiento y síndromes geriátricos, los beneficios del ejercicio y la actividad física en los adultos mayores serán más tangibles.Por lo tanto, el primer propósito de la presente revisión fueinvestigar los mecanismos de actividad física y ejercicios que están involucrados en la prevención de enfermedades relacionadas con el envejecimiento y síndrome geriátricoutilizando la evidencia actual (de2015 en adelante).Además, el propósito de este estudio fue proporcionar una guía de ejercicio (entrenamiento aeróbico y de resistencia) basada en evidencia reciente (de2015 en adelante)