111,991 research outputs found
Multi-frequency imaging of perfectly conducting cracks via boundary measurements
Imaging of perfectly conducting crack(s) in a 2-D homogeneous medium using
boundary data is studied. Based on the singular structure of the Multi-Static
Response (MSR) matrix whose elements are normalized by an adequate test
function at several frequencies, an imaging functional is introduced and
analyzed. A non-iterative imaging procedure is proposed. Numerical experiments
from noisy synthetic data show that acceptable images of single and multiple
cracks are obtained.Comment: 4 pages, 3 figure
Separation of gas mixtures by centrifugation
Magnetohydrodynamic (MHD) centrifuge utilizing electric currents and magnetic fields produces a magnetic force which develops supersonic rotational velocities in gas mixtures. Device is superior to ordinary centrifuges because rotation of gas mixture is produced by MHD force rather than mechanical means
Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies. Therefore, understanding the mediators involved in their pathophysiology is necessary for the development of therapeutic strategies. To this end, the hydrolase activity of soluble epoxide hydrolase (sEH) has been explored in the context of several eye diseases, due to its implications in vascular diseases through metabolism of bioactive epoxygenated fatty acids. In this mini-review, we discuss the mounting evidence associating sEH with ocular diseases and its therapeutic value as a target. Substantial data link sEH with the retinal and choroidal neovascularization underlying diseases such as wet age-related macular degeneration, retinopathy of prematurity, and proliferative diabetic retinopathy, although some conflicting results pose challenges for the synthesis of a common mechanism. sEH also shows therapeutic relevance in non-proliferative diabetic retinopathy and diabetic keratopathy, and sEH inhibition has been tested in a uveitis model. Various approaches have been implemented to assess sEH function in the eye, including expression analyses, genetic manipulation, pharmacological targeting of sEH, and modulation of certain lipid metabolites that are upstream and downstream of sEH. On balance, sEH inhibition shows considerable promise for treating multiple eye diseases. The possibility of local delivery of inhibitors makes the eye an appealing target for future sEH drug development initiatives
Comment on "Spectroscopic Evidence for Multiple Order Parameter Components in the Heavy Fermion Superconductor CeCoIn"
Recently, Rourke et al. reported point-contact spectroscopy results on the
heavy-fermion superconductor CeCoIn [1]. They obtained conductance spectra
on the c-axis surfaces of CeCoIn single crystals. Their major claims are
two-fold: CeCoIn has i) d-wave pairing symmetry and ii) two coexisting
order parameter components. In this Comment, we show that these claims are not
warranted by the data presented. [1] Rourke et al., Phys. Rev. Lett. 94, 107005
(2005).Comment: accepted for publication in Phys. Rev. Lett., final for
Polymer Translocation througha Pore in a Membrane
We construct a new statistical physical model of polymer translocation
through a pore in a membrane treated as the diffusion process across a free
energy barrier. We determine the translocation time in terms of chain
flexibility yielding an entropic barrier, as well as in terms of the driving
mechanisms such as transmembrane chemical potential difference and Brownian
ratchets. It turns out that, while the chemical potential differences induce
pronounced effects on translocation due to the long-chain nature of the
polymer, the ratchets suppress this effect and chain flexibility.Comment: 4 pages, 5 figures, published in Phys. Rev. Lett. 77, 783(1996
Mean Field Theoretical Structure of He and Be Isotopes
The structures of He and Be even-even isotopes are investigated using an
axially symmetric Hartree-Fock approach with a Skyrme-IIIls mean field
potential. In these simple HF calculations, He and Be isotopes appear to be
prolate in their ground states and Be isotopes have oblate shape isomeric
states. It is also shown that there exists a level crossing when the nuclear
shape changes from the prolate state to the oblate state. The single neutron
levels of Be isotopes exhibit a neutron magic number 6 instead of 8 and show
that the level inversion between 1/2- and 1/2+ levels occurs only for a largely
deformed isotope. Protons are bound stronger in the isotope with more neutrons
while neutron levels are somewhat insensitive to the number of neutrons and
thus the nuclear size and also the neutron skin become larger as the neutron
number increases. In these simple calculations with Skyrme-IIIls interaction no
system with a clear indication of neutron halo was found among He and Be
isotopes. Instead of it we have found 8He+2n, 2n+8He+2n, and 16Be+2n like chain
structures with clusters of two correlated neutrons. It is also shown that 8He
and 14Be in their ground states are below the neutron drip line in which all
nucleons are bound with negative energy and that 16Be in its ground state is
beyond the neutron drip line with two neutrons in positive energy levels.Comment: CM energy correction, 1 figure and more discussions adde
Field Theoretic Approach to Long Range Reactions
We analyze bimolecular reactions that proceed by a long-ranged reactive
interaction, using a field theoretic approach that takes into account
fluctuations.
We consider both the one-species, reaction and the
two-species, reaction. We consider both mobile and immobile
reactants, both in the presence and in the absence of adsorption.Comment: 9 pages. 4 figures. Uses svjour macros. To appear in Europ. Phys. J.
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