540 research outputs found
Pure spinor computation towards open string three-loop
Using the recent results in the pure spinor formulation, we lay out a
ground-work towards the full momentum space amplitudes of open superstrings at
three-loop. After briefly reviewing the one-loop amplitude, we directly work
out the two-loop and reproduce the result that was obtained by a symmetry
argument. For the three-loop, first we use the two-loop regulator as a warm-up
exercise. The result vanishes. We then employ the regulator that has been
recently proposed by Aisaka and Berkovits (AB). It is noted that the terms in
higher power in that render the two-loop
regulator disqualified for the three-loop do not contribute. This with a few
other indications suggests a possibility that the AB regulator might also lead
to a vanishing result. Nevertheless, we argue that it is possible to acquire
the three-loop amplitude, and present a result that we anticipate to be the
three-loop amplitude.Comment: 41 pages, latex, cosmetic change
Use of MHC class I or II 'knock out' mice to delineate the role of these molecules in acceptance/rejection of xenografts
Effect of tacrolimus and splenectomy on engraftment and GVHD after bone marrow xenotransplantation in the reciprocal hamster to rat animal models
In-situ upgrading of Napier grass pyrolysis vapour over microporous and hierarchical mesoporous zeolites
This study presents in-situ upgrading of pyrolysis
vapour derived from Napier grass over microporous and
mesoporous ZSM-5 catalysts. It evaluates effect of process
variables such catalyst–biomass ratio and catalyst type in
a vertical fixed bed pyrolysis system at 600 °C, 50 °C/min
under 5 L/min nitrogen flow. Increasing catalyst–biomass
ratio during the catalytic process with microporous structure
reduced production of organic phase bio-oil by approximately
7.0 wt%. Using mesoporous catalyst promoted
nearly 4.0 wt% higher organic yield relative to microporous
catalyst, which translate to only about 3.0 wt% reduction
in organic phase compared to the yield of organic phase
from non-catalytic process. GC–MS analysis of bio-oil
organic phase revealed maximum degree of deoxygenation
of about 36.9% with microporous catalyst compared to
the mesoporous catalysts, which had between 39 and 43%.
Mesoporous catalysts promoted production olefins and
alkanes, normal phenol, monoaromatic hydrocarbons while
microporous catalyst favoured the production of alkenes
and polyaromatic hydrocarbons. There was no significant increase in the production of normal phenols over microporous catalyst due to its inability to transform the methoxyphenols and methoxy aromatics. This study demonstrated that upgrading of Napier grass pyrolysis vapour over mesoporous ZSM-5 produced bio-oil with improved physicochemical properties
Is lymphovascular invasion a powerful predictor for biochemical recurrence in pT3 N0 prostate cancer?: Results from the K-CaP database
To assess the impact of lymphovascular invasion (LVI) on the risk of biochemical recurrence (BCR) in pT3 N0 prostate cancer, clinical data were extracted from 1,622 patients with pT3 N0 prostate cancer from the K-CaP database. Patients with neoadjuvant androgen deprivation therapy (n = 325) or insufficient pathologic or follow-up data (n = 87) were excluded. The primary endpoint was the oncologic importance of LVI, and the secondary endpoint was the hierarchical relationships for estimating BCR between the evaluated variables. LVI was noted in 260 patients (21.5%) and was significantly associated with other adverse clinicopathologic features. In the multivariate Cox regression analysis, LVI was significantly associated with an increased risk of BCR after adjusting for known prognostic factors. In the Bayesian belief network analysis, LVI and pathologic Gleason score were found to be first-degree associates of BCR, whereas prostate-specific antigen (PSA) level, seminal vesicle invasion, perineural invasion, and high-grade prostatic intraepithelial neoplasia were considered second-degree associates. In the random survival forest, pathologic Gleason score, LVI, and PSA level were three most important variables in determining BCR of patients with pT3 N0 prostate cancer. In conclusion, LVI is one of the most powerful adverse prognostic factors for BCR in patients with pT3 N0 prostate cancer.1132Ysciescopu
Unassisted photoelectrochemical water splitting exceeding 7% solar to hydrogen conversion efficiency using photon recycling
Various tandem cell configurations have been reported for highly efficient and spontaneous hydrogen production from photoelectrochemical solar water splitting. However, there is a contradiction between two main requirements of a front photoelectrode in a tandem cell configuration, namely, high transparency and high photocurrent density. Here we demonstrate a simple yet highly effective method to overcome this contradiction by incorporating a hybrid conductive distributed Bragg reflector on the back side of the transparent conducting substrate for the front photoelectrochemical electrode, which functions as both an optical filter and a conductive counter-electrode of the rear dye-sensitized solar cell. The hybrid conductive distributed Bragg reflectors were designed to be transparent to the long-wavelength part of the incident solar spectrum (lambda>500 nm) for the rear solar cell, while reflecting the short-wavelength photons (lambda<500 nm) which can then be absorbed by the front photoelectrochemical electrode for enhanced photocurrent generation.114129Ysciescopu
On effective actions of BPS branes and their higher derivative corrections
We calculate in detail the disk level S-matrix element of one Ramond-Ramond
field and three gauge field vertex operators in the world volume of BPS branes,
to find four gauge field couplings to all orders of up to on-shell
ambiguity. Then using these infinite couplings we find that the massless pole
of the field theory amplitude is exactly equal to the massless pole S-matrix
element of this amplitude for the case to all orders of .
Finally we show that the infinite massless poles and the contact terms of this
amplitude for the case can be reproduced by the Born-Infeld action and
the Wess-Zumino actions and by their higher derivative corrections.Comment: 26 pages, 2 figures, minor corrections,references added and version
published in JHE
Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis
<p>Abstract</p> <p>Background</p> <p>In contrast to tumor-suppressive apoptosis and autophagic cell death, necrosis promotes tumor progression by releasing the pro-inflammatory and tumor-promoting cytokine high mobility group box 1 (HMGB1), and its presence in tumor patients is associated with poor prognosis. Thus, necrosis has important clinical implications in tumor development; however, its molecular mechanism remains poorly understood.</p> <p>Results</p> <p>In the present study, we show that Distal-less 2 (Dlx-2), a homeobox gene of the Dlx family that is involved in embryonic development, is induced in cancer cell lines dependently of reactive oxygen species (ROS) in response to glucose deprivation (GD), one of the metabolic stresses occurring in solid tumors. Increased Dlx-2 expression was also detected in the inner regions, which experience metabolic stress, of human tumors and of a multicellular tumor spheroid, an <it>in vitro </it>model of solid tumors. Dlx-2 short hairpin RNA (shRNA) inhibited metabolic stress-induced increase in propidium iodide-positive cell population and HMGB1 and lactate dehydrogenase (LDH) release, indicating the important role(s) of Dlx-2 in metabolic stress-induced necrosis. Dlx-2 shRNA appeared to exert its anti-necrotic effects by preventing metabolic stress-induced increases in mitochondrial ROS, which are responsible for triggering necrosis.</p> <p>Conclusions</p> <p>These results suggest that Dlx-2 may be involved in tumor progression via the regulation of metabolic stress-induced necrosis.</p
Quark-antiquark potential in AdS at one loop
We derive an exact analytical expression for the one-loop partition function
of a string in AdS_5xS^5 background with world-surface ending on two
anti-parallel lines. All quantum fluctuations are shown to be governed by
integrable, single-gap Lame' operators. The first strong coupling correction to
the quark-antiquark potential, as defined in N=4 SYM, is derived as the sum of
known mathematical constants and a one-dimensional integral representation. Its
full numerical value can be given with arbitrary precision and confirms a
previous result.Comment: 16 pages. Typos corrected, minor change
Direct nitrogen fixation at the edges of graphene nanoplatelets as efficient electrocatalysts for energy conversion
Nitrogen fixation is essential for the synthesis of many important chemicals (e.g., fertilizers, explosives) and basic building blocks for all forms of life (e.g., nucleotides for DNA and RNA, amino acids for proteins). However, direct nitrogen fixation is challenging as nitrogen (N2) does not easily react with other chemicals. By dry ball-milling graphite with N2, we have discovered a simple, but versatile, scalable and eco-friendly, approach to direct fixation of N2 at the edges of graphene nanoplatelets (GnPs). The mechanochemical cracking of graphitic C-C bonds generated active carbon species that react directly with N2 to form five- and six-membered aromatic rings at the broken edges, leading to solution-processable edge-nitrogenated graphene nanoplatelets (NGnPs) with superb catalytic performance in both dye-sensitized solar cells and fuel cells to replace conventional Pt-based catalysts for energy conversion.open302
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