CYCLIC GMP: A SATIETY SIGNAL IN C. ELEGANS

Appetite control and satiety mechanisms help animals maintain energy homeostasis; however, these mechanisms can be misregulated, leading to overweight and obesity. Caenorhabditis elegans is an excellent model system to study appetite and satiety because of its conserved behavioral aspects of satiety and conserved molecular mechanisms. ASI senses nutrition and its activity is required for the behavioral state of satiety quiescence. The purpose of this thesis project was to elucidate the function of cGMP signaling in ASI by looking at behavioral effects from the pharmacological use of sildenafil (Viagra), a PDE inhibitor, and the effects on ASI activation from mutating guanylyl cyclase DAF-11. Sildenafil treatment increases satiety quiescence and decreases fat storage in a PDE-dependent manner. The daf-11 mutation decreased overall fluorescence intensity of ASI activation and the frequency at which ASI activated by about 50% compared to wild-type worms, suggesting that DAF-11 plays an important role in ASI to promote satiety

PILOTs: What Are They and Are They Affected by Institutional and/or Economic Constraints? The Case of Wisconsin Municipalities

Following the rise of tax and expenditure limitations in the 1970s, scholars have focused on assessing the effects of these limitations on local government fiscal outcomes. One key takeaway has been local governments’ decreasing reliance on property taxes and increased use of nontax revenue sources, in particular fees and changes. This study builds on this work by focusing on a particular type of fee—that is, payments in lieu of taxes (PILOTs). We find that, in Wisconsin, revenues received by municipalities from two PILOTs programs are affected quite differently. The extent to which the economy, municipal fiscal condition, tax and expenditure limits, and community characteristics affect PILOTs’ revenues depends on the extent to which the municipality can manipulate the payment structure

Observation of diurnal variations in mesoscale eddy sea-surface currents using GOCI data

The surface current field of a mesoscale eddy in the East Sea (Sea of Japan) was derived from consecutive Geostationary Ocean Color Imager chlorophyll-a (chl-a) concentration images using the normalized maximum cross-correlation method. The estimated current field of the eddy exhibited anticyclonic structure demonstrated by the objective dynamic thresholds of correlation coefficients. The eddy periphery was defined by fitting an ellipse to subjectively selected points from the frontal map of chl-a concentration data. Radial distribution and hourly variation of the current speed around the eddy were presented. In terms of the magnitude and direction, the estimated current field was in good agreement with altimeter-based current field and current vectors from surface drifters. Diurnal variations in the current speeds of the mesoscale eddies showed a quadratic relation to the wind speed

Quenched Fe Moment in the Collapsed Tetragonal Phase of Ca1−x_{1-x}Prx_{x}Fe2_2As2_2

We report $^{75}$As NMR studies on single crystals of rare-earth doped iron pnictides superconductor Ca$_{1-x}$Pr$_{x}$Fe$_{2}$As$_{2}$ ($x$=0.075 and 0.15). The $^{75}$As spectra show a chemical pressure effect with doping and a first order structure transition to the collapsed tetragonal phase upon cooling. A sharp drop of the Knight shift is seen below the structural transition, whereas $1/T_1$ is strongly enhanced at low-temperatures. These evidences indicate quenching of Fe local magnetism and short-range ordering of Pr$^{3+}$ moment in the collapsed tetragonal phase. The quenched Fe moment through structure collapse suggests a strong interplay of structure and magnetism, which is important for understanding the nature of the collapsed tetragonal phase.Comment: 5 pages, 5 figure

Experimental observation of hidden Berry curvature in inversion-symmetric bulk 2H-WSe2

We investigate the hidden Berry curvature in bulk 2H-WSe2 by utilizing the surface sensitivity of angle resolved photoemission (ARPES). The symmetry in the electronic structure of transition metal dichalcogenides is used to uniquely determine the local orbital angular momentum (OAM) contribution to the circular dichroism (CD) in ARPES. The extracted CD signals for the K and K' valleys are almost identical but their signs, which should be determined by the valley index, are opposite. In addition, the sign is found to be the same for the two spin-split bands, indicating that it is independent of spin state. These observed CD behaviors are what are expected from Berry curvature of a monolayer of WSe2. In order to see if CD-ARPES is indeed representative of hidden Berry curvature within a layer, we use tight binding analysis as well as density functional calculation to calculate the Berry curvature and local OAM of a monolayer WSe2. We find that measured CD-ARPES is approximately proportional to the calculated Berry curvature as well as local OAM, further supporting our interpretation.Comment: 6 pages, 3 figure

High Performance Electrocatalysts Based on Pt Nanoarchitecture for Fuel Cell Applications

Fuel cells, converting chemical energy from fuels into electricity directly without the need for combustion, are promising energy conversion devices for their potential applications as environmentally friendly, energy efficient power sources. However, to take fuel cell technology forward towards commercialization, we need to achieve further improvements in electrocatalyst technology, which can play an extremely important role in essentially determining cost-effectiveness, performance, and durability. In particular, platinum- (Pt-) based electrocatalyst approaches have been extensively investigated and actively pursued to meet those demands as an ideal fuel cell catalyst due to their most outstanding activity for both cathode oxygen reduction reactions and anode fuel oxidation reactions. In this review, we will address important issues and recent progress in the development of Pt-based catalysts, their synthesis, and characterization. We will also review snapshots of research that are focused on essential dynamics aspects of electrocatalytic reactions, such as the shape effects on the catalytic activity of Pt-based nanostructures, the relationships between structural morphology of Pt-based nanostructures and electrochemical reactions on both cathode and anode electrodes, and the effects of composition and electronic structure of Pt-based catalysts on electrochemical reaction properties of fuel cells.</jats:p