1,051 research outputs found

    Analysis of the Doctor of Public Health (DrPH) training and identity needs in the United States: a qualitative study

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    Background The Doctor of Public Health (DrPH) is the highest attainable degree in the field of public health, specifically designed to prepare professionals to address complex public health challenges in practical settings. This study was designed to explore the importance of achieving a shared and uniform understanding of DrPH education, assess the optimal direction for DrPH training, and investigate the specific curriculum requirements by gathering insights from current DrPH students and alumni in the United States. Methods A total of 13 focus group discussions and two in-depth interviews (total participants: 50) were conducted through Zoom to see how DrPH students and alumni assessed their DrPH educational programs. Results Three overarching findings emerged from the analysis of focus group discussions and in-depth interviews. First, participants expressed a preference against a national DrPH board examination, but advocated for a standardized common core curriculum that extends across the entire nation. Second, the ideal direction for DrPH training was perceived to involve a practice-based approach, emphasizing the importance of multi-, inter-, and trans-disciplinary instruction delivered by faculty with practical experience. Last, there was a demand for a DrPH-specific unique curriculum encompassing areas such as mixed method analysis, leadership and management, applied communication, crisis and change management, proficiency in addressing contemporary topics, and tailored applied and integrative learning requirements specific to the DrPH program. Conclusions We explored a range of DrPH training and identity needs among 50 participants, comprised of students and alumni who directly benefit from DrPH education. By considering these inputs, individuals from institutions that offer the DrPH degree can further enhance the quality of public health practice training and make significant contributions to the overall advancement of the field of public health

    Role of Endomucin in Hypoxia-Induced Retinopathy of Prematurity

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    Retinopathy of prematurity (ROP) is a major cause of blindness among premature, low birth weight infants as a result of pathological angiogenesis. Angiogenesis, the growth of new blood vessels from preexisting vessels, occurs in the veins and capillaries of the body. The process is highly regulated during early development and maturation. However, under abnormal conditions such as a decrease in oxygen levels or hypoxia, angiogenesis can become dysregulated and pathogenic. Currently, the best treatment for ROP is laser therapy, which does not significantly improve vision. Alternatively, glycoproteins are believed to play an important role in angiogenesis. Endomucin (EMCN), a glycoprotein, has been shown to be expressed by the venous and capillary endothelium. EMCN is believed to be associated with angiogenesis and could be a potential target for treatment of ROP. Thus, we hypothesize that EMCN is regulated by hypoxia and plays an important role in pathological angiogenesis. Human retinal endothelial cells (HRECs), representative of endothelial cells involved in retinal angiogenesis, were deprived of oxygen using a hypoxia chamber. We established the optimal oxygen dosage, determined the optimal cell density, and monitored EMCN expression at different time points after exposure to hypoxia. Changes in gene expression in response to hypoxia were compared to control cells. Our preliminary data indicates that EMCN is regulated by hypoxia. Currently, we are investigating whether EMCN has similar effects in regulating revascularization in vivo. Taken together, our study indicates a novel role for EMCN during hypoxia-induced angiogenesis which may serve as a therapeutic target

    THE IMPACT OF ACTIVE LEARNING WITH ADAPTIVE LEARNING SYSTEMS IN GENERAL EDUCATION INFORMATION TECHNOLOGY COURSES

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    An adaptive learning system is an effective educational tool that meets the individual needs of students, but it is limited in fostering student learning by itself. With active engagement, students learn better than with adaptive learning systems alone. In this study, we investigate the impact of an adaptive learning system with active learning projects on student learning in general education information technology courses. We believe that today\u27s classroom calls for adaptive learning to serve the needs of diverse student populations. Active learning through real-life hands-on learning activities can enhance student learning by allowing them to apply their knowledge to authentic projects. In the classroom, we often find that learning computing with authentic hands-on activities is not only useful, but it contributes to improving student motivation and confidence

    Fixed-point Grover Adaptive Search for QUBO Problems

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    We apply and study a Grover-type method for Quadratic Unconstrained Binary Optimization (QUBO) problems. First, we construct a marker oracle for such problems. For an nn-dimensional QUBO problem, these oracles have circuit depth and gate count of O(n2)O \left( n^2 \right). We also develop a novel Fixed-point Grover Adaptive Search for QUBO Problems, using our oracle design and a hybrid Fixed-point Grover Search of Li et al. [9]. This method has better performance guarantees than the Grover Adaptive Search of Gilliam et al. [5].Comment: 16 pages; submitted version. Comments are welcome

    Determination of Thyroid Volume by Ultrasonography among Schoolchildren in Philippines

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    Objective. Iodine deficiency is defined by the goiter and the urinary iodine concentration. However, a lack of local thyroid volume reference data resulted in the vague definition of goiter, especially in school-aged children. The aim of this paper was to determine the thyroid volumes by ultrasonography in schoolchildren aged 6 to 12 years living in Cagayan areas in Philippine. Methods. Cross-sectional thyroid ultrasonographic data of 158 schoolchildren aged 6–12 years from Tuguegarao and Lagum in Cagayan valley, Philippine were used. Thyroid volumes were compared based on logistic issue and urban and rural area and compared with other previously reported data. Results. The mean values of thyroid volume in Tuguerago and Lagum were 2.99 ± 1.34 mL and 2.42 ± 0.92 mL. The thyroid size was significantly in association with age (P < 0.00), weight (P < 0.00), height (P < 0.00), and BSA (P < 0.00) by Pearson's correlation. The median thyroid volumes of schoolchildren investigated in this study were generally low compared to international reference data by age group but not by BSA. Conclusions. We propose for the first time local reference ultrasound values for thyroid volumes in 6–12 aged schoolchildren that should be used for monitoring iodine deficiency disorders

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