TORSO DEFORMATION IN FRONTAL SLED TESTS: COMPARISION BETWEEN THOR NT, THOR NT WITH THE CHALMERS SD-1 SHOULDER, AND PMHS

This study compares the thoracic deformation response of the 50th percentile male THOR NT frontal crash dummy and the response of the THOR modified with the SD-1 shoulder (THOR SD-1) relative to the thoracic response of eight 50th percentile male PMHS. The prototype Chalmers University SD-1 shoulder was designed to be more human-like in terms of geometry and range of motion in comparison to the standard THOR NT shoulder. The dummies and PMHS were restrained by a three-point restraint in a driver-side configuration and were subjected to a simulated 40 km/h frontal crash. The most prominent difference between the responses of the dummies and PMHS involved motion of the lower right anterior ribcage measurement site that is the farthest lateral distance from the diagonal shoulder belt. During the impact event, this site moved substantially anteriorly and away from the spine for the PMHS. The PMHS lower right “bulge out” behavior is believed to be caused by inertial loading of the ribcage, underlying organs, and soft tissue overlying the torso. The THOR SD-1 shoulder altered the shoulder belt position relative to the thoracic deflection measurement sites resulting in a different distribution of deformation for the upper measurement sites although the average upper site deformation was similar to that recorded for the standard THOR shoulder

Perceptual grouping based on iterative multi-scale tensor voting

Abstract. We propose a new approach for perceptual grouping of oriented segments in highly cluttered images based on tensor voting. Segments are represented as second-order tensors and communicate with each other through a voting scheme that incorporates the Gestalt principles of visual perception. An iterative scheme has been devised which removes noise segments in a conservative way using multi-scale analysis and re-voting. We have tested our approach on data sets composed of real objects in real backgrounds. Our experimental results indicate that our method can segment successfully objects in images with up to twenty times more noise segments than object ones.

Compositional nutrient diagnosis (CND) de la vigne au Bresil.

The grapevine (Vittis vinifera) is an important production in Brazil. Grapevine fertilization is guided mainly by foliar analysis. Research was conducted in 2014/2015 in the largest vine-producing region in the State of Rio Grande do Sul, Brazil. The objective was to compare common nutrient concentration ranges from literature to diagnostic standards using compositional nutrient diagnosis (CND) across 81 commercial vineyar

Experimental study of fire containment using water mist curtains in a reduced-scale deck of a ro-ro ship

Experiments have been conducted to evaluate the containment of smoke and heat using water mist curtains in a model setup of a ro-ro ship's cargo deck with a scale of 1:13, providing practical insights into the application of such fire protection systems in the cargo deck as well as valuable data for future numerical simulations. In this regard, the requirements of the international convention of Safety of Life at Sea (SOLAS) are studied for the side openings of so-called ‘open decks’ in comparison with ‘closed decks’, especially to examine the feasibility of using water mist curtains for creating isolated subdivisions in the ro-ro space as a fire management strategy. The water mist curtains are created with one or two rows of water mist nozzles at pressures ranging from 3 to 8 bar, while the source of smoke and heat is a liquid pool fire, and inert cargo items are used in some experiments. Correspondingly, the interaction between the water mist curtain(s) and the fire is evaluated in terms of its heat release rate, and the containment effect is quantified via measurements of smoke flow through the deck and through the windows, concentrations of gaseous species, as well as gas temperatures at various key locations. The study shows that water mist curtains have a strong effect on fire dynamics and smoke propagation, but containment is dependent on the configuration of side openings and the location of fire, among other important factors

Planning and Leveraging Event Portfolios: Towards a Holistic Theory

This conceptual paper seeks to advance the discourse on the leveraging and legacies of events by examining the planning, management, and leveraging of event portfolios. This examination shifts the common focus from analyzing single events towards multiple events and purposes that can enable cross-leveraging among different events in pursuit of attainment and magnification of specific ends. The following frameworks are proposed: (1) event portfolio planning and leveraging, and (2) analyzing events networks and inter-organizational linkages. These frameworks are intended to provide, at this infancy stage of event portfolios research, a solid ground for building theory on the management of different types and scales of events within the context of a portfolio aimed to obtain, optimize and sustain tourism, as well as broader community benefits

Translational and Regulatory Challenges for Exon Skipping Therapies

Several translational challenges are currently impeding the therapeutic development of antisense-mediated exon skipping approaches for rare diseases. Some of these are inherent to developing therapies for rare diseases, such as small patient numbers and limited information on natural history and interpretation of appropriate clinical outcome measures. Others are inherent to the antisense oligonucleotide (AON)-mediated exon skipping approach, which employs small modified DNA or RNA molecules to manipulate the splicing process. This is a new approach and only limited information is available on long-term safety and toxicity for most AON chemistries. Furthermore, AONs often act in a mutation-specific manner, in which case multiple AONs have to be developed for a single disease. A workshop focusing on preclinical development, trial design, outcome measures, and different forms of marketing authorization was organized by the regulatory models and biochemical outcome measures working groups of Cooperation of Science and Technology Action: "Networking towards clinical application of antisense-mediated exon skipping for rare diseases." The workshop included participants from patient organizations, academia, and members of staff from the European Medicine Agency and Medicine Evaluation Board (the Netherlands). This statement article contains the key outcomes of this meeting.status: publishe

Long-term outcome after early infrainguinal graft failure

AbstractPurpose: To determine the long-term outcome and prognostic factors after early infrainguinal graft failure (<30 days).Methods: Retrospective analysis of limb salvage data, patency data, and prognostic risk factors in 112 new infrainguinal bypass grafts from 1985 to 1995 that occluded within 30 days of operation.Result: Thirty-six femoropopliteal and 76 femorotibial/femoropedal arterial bypass (“index”) procedures were performed for rest pain (50%), tissue loss (31%), or disabling claudication (19%). In 103 patients, an immediate additional revascularization (“takeback”) procedure was performed at the time of early graft failure. Life table analysis of the takeback procedures for threatened limbs (n = 84) revealed limb salvage rates of 74%, 54%, 40%, and 31% at 1 month, 1 year, 3 years, and 5 years, respectively. The 1-month limb salvage rate (threatened limbs) was 12% (1 of 8) in patients who were not taken back for revascularization and 33% (4 of 12) in patients who had undergone more than one takeback procedure within 30 days. The secondary graft patency rates for the takeback procedures (n = 103) were 70%, 37%, 27%, and 23% at 1 month, 1 year, 3 years, and 5 years, respectively. Univariate and life table analysis revealed that patients who were given anticoagulation medication after the index procedure (before graft thrombosis) or patients who had undergone previous ipsilateral leg revascularization had significantly lower rates of limb salvage and graft patency (p < 0.05). The limb salvage rate was also significantly worse in patients who had single-vessel runoff compared with those who had multiple-vessel runoff (p < 0.01). Thrombectomy and revision or complete graft replacement had a better secondary patency rate than thrombectomy alone (p < 0.05). Autogenous vein grafts had better outcome than polytetrafluoroethylene-containing grafts, but statistical significance was not achieved. No significant differences in limb salvage or graft patency rates were found between femoropopliteal versus femorotibial/femoropedal bypass grafting, age, gender, previous inflow surgery, diabetes, hypertension, smoking, or cardiac, renal, or pulmonary disease.Conclusion: The long-term limb salvage and graft patency rates after takeback revascularization procedures for early graft failure are poor. Despite poor outcome, a single takeback procedure appears warranted in all patients. Multiple takeback procedures, however, do not appear to be justified, especially in patients who are given anticoagulation medication after the index bypass procedure, repeat leg bypass procedures, or if there is no potential for graft revision

Stokes Parameters as a Minkowskian Four-vector

It is noted that the Jones-matrix formalism for polarization optics is a six-parameter two-by-two representation of the Lorentz group. It is shown that the four independent Stokes parameters form a Minkowskian four-vector, just like the energy-momentum four-vector in special relativity. The optical filters are represented by four-by-four Lorentz-transformation matrices. This four-by-four formalism can deal with partial coherence described by the Stokes parameters. A four-by-four matrix formulation is given for decoherence effects on the Stokes parameters, and a possible experiment is proposed. It is shown also that this Lorentz-group formalism leads to optical filters with a symmetry property corresponding to that of two-dimensional Euclidean transformations.Comment: RevTeX, 22 pages, no figures, submitted to Phys. Rev.