Cognitive topography imbalance in alcoholism and psychiatric comorbidity

peer reviewe

Compulsive Personality as Predictor of Response to Serotoninergic Antidepressants

Peer reviewe

Controlled Comparison of Milnacipran and Fluoxetine in Major Depression

The efficacy and the tolerance of milnacipran (100 mg/day), a second generation antidepressant which equipotently inhibits both noradrenaline and serotonin reuptake, was compared to fluoxetine (20 mg/day), a selective serotonin reuptake inhibitor, in two parallel groups of, respectively, 97 and 93 major depressive outpatients. The duration of the study was 6 weeks, with assessments every 2 weeks by means of the Montgomery and Asberg depression scale (MADRS), the Hamilton depression scale, the clinical global impressions (CGI), and a checklist of symptoms and side-effects. Results showed significant superiority of fluoxetine over milnacipran on most rating instruments: MADRS (P = 0.01) including five individual items, Hamilton depression scale (P = 0.002) including ten individual items, CGI of severity (P = 0.01) and therapeutical index (P = 0.002). On visual analogue scales assessing the clinical profile of the compounds, fluoxetine was rated as exhibiting more psychostimulating activity than milnacipran (P = 0.0008). The tolerance of the two antidepressants was very similar, with the exception of symptoms of dizziness which were more frequently reported with milnacipran (P = 0.01). These differences in efficacy favoring fluoxetine could result from the selection of a dose of milnacipran below the optimal therapeutic dose for this type of psychiatric patients or to the administration of the compounds in single daily intakes, whereas milnacipran possesses a plasma elimination half-life of only 7 h.Peer reviewe

Intersectionality and gender mainstreaming in international health: Using a feminist participatory action research process to analyse voices and debates from the global south and north

Critiques of gender mainstreaming (GM) as the officially agreed strategy to promote gender equity in health internationally have reached a critical mass. There has been a notable lack of dialogue between gender advocates in the global north and south, from policy and practice, governments and nongovernmental organisations (NGOs). This paper contributes to the debate on the shape of future action for gender equity in health, by uniquely bringing together the voices of disparate actors, first heard in a series of four seminars held during 2008 and 2009, involving almost 200 participants from 15 different country contexts. The series used (Feminist) Participatory Action Research (FPAR) methodology to create a productive dialogue on the developing theory around GM and the at times disconnected empirical experience of policy and practice. We analyse the debates and experiences shared at the seminar series using concrete, context specific examples from research, advocacy, policy and programme development perspectives, as presented by participants from southern and northern settings, including Kenya, Mozambique, India, the Democratic Republic of Congo, Canada and Australia. Focussing on key discussions around sexualities and (dis)ability and their interactions with gender, we explore issues around intersectionality across the five key themes for research and action identified by participants: 1) Addressing the disconnect between gender mainstreaming praxis and contemporary feminist theory; 2) Developing appropriate analysis methodologies; 3) Developing a coherent theory of change; 4) Seeking resolution to the dilemmas and uncertainties around the ‘place’ of men and boys in GM as a feminist project; and 5) Developing a politics of intersectionality. We conclude that there needs to be a coherent and inclusive strategic direction to improve policy and practice for promoting gender equity in health which requires the full and equal participation of practitioners and policy makers working alongside their academic partners

Troubles psychiatriques et dangerosité

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Dépression: Intérêt de la variation contingente négative

peer reviewe

Into the Future

http://digilib.usm.edu/cdm/compoundobject/collection/art/id/396/rec/59 Etching, Aquatint, and Carborundum with Collage on embossed paper, 24 x 31 Printer Robert Dutrou, Atelier Morsang Signed in pencil bottom right, E.A. 3/12. LOK 2003.63.2 Donation by the artist, ca. 1987https://aquila.usm.edu/cookartgallery_perm/1026/thumbnail.jp

Planifications urbaines et pratiques sociales en Finlande (De la ville industrielle du xixe siècle à la ville fonctionnaliste des années 1930)

Le choix du titre de cette intervention s’explique par la volonté de mettre en relief deux aspects essentiels si l’on veut comprendre l’évolution urbaine des villes finlandaises : – D’une part, ce sont des villes qui, tout au long de leur histoire, se développent essentiellement selon les règles précises de plans d’urbanisme. La Finlande, pays colonisé par la Suède dès le XIIe siècle, puis Grand-Duché de l’Empire tsariste, connaît d’abord le plan en damier caractéristique des villes coloniale..