Enhancing Decision Support for Secondary Education with OLAP

Decision-making is one of the most critical processes taking place in a modern school. It is a necessary competence for school administrators and managerial staff especially in Education Directorates who often have to make decisions regarding the implementation of education strategies and policies. It is also important for teaching staff and school curriculum designers in order to plan teaching methods and monitor student performance. Nowadays many school functions are supported by dedicated information systems. Business Intelligence (BI) is a widely used set of techniques and tools for the transformation of raw data into meaningful and useful information for business analysis purposes. They include Online Analytical Processing (OLAP) in order to provide historical, current and predictive views of business operations. Schools in secondary education can be viewed as small organizations where effective decision making is required at many areas and levels. The aim of this project is the research of feasibility of applying OLAP Decision Support Systems in Education and Education Management, any possible benefits as well as possible enhancements. The outcome is the design and implementation of an enhanced OLAP system applied in a specific educational setting based on our case study

Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells

Sirtuin-1 (SIRT1) and SIRT6, NAD(+)-dependent Class III protein deacetylases, are putative anti-aging enzymes, down-regulated in patients with chronic obstructive pulmonary disease (COPD), which is characterized by the accelerated ageing of the lung and associated with increased oxidative stress. Here, we show that oxidative stress (hydrogen peroxide) selectively elevates microRNA-34a (miR-34a) but not the related miR-34b/c, with concomitant reduction of SIRT1/-6 in bronchial epithelial cells (BEAS2B), which was also observed in peripheral lung samples from patients with COPD. Over-expression of a miR-34a mimic caused a significant reduction in both mRNA and protein of SIRT1/-6, whereas inhibition of miR-34a (antagomir) increased these sirtuins. Induction of miR-34a expression with H2O2 was phosphoinositide-3-kinase (PI3K) dependent as it was associated with PI3Kα activation as well as phosphatase and tensin homolog (PTEN) reduction. Importantly, miR-34a antagomirs increased SIRT1/-6 mRNA levels, whilst decreasing markers of cellular senescence in airway epithelial cells from COPD patients, suggesting that this process is reversible. Other sirtuin isoforms were not affected by miR-34a. Our data indicate that miR-34a is induced by oxidative stress via PI3K signaling, and orchestrates ageing responses under oxidative stress, therefore highlighting miR-34a as a new therapeutic target and biomarker in COPD and other oxidative stress-driven aging diseases

TRIASSIC CARBONATE AND EVAPORITE SEDIMENTATION IN THE IONIAN ZONE (WESTERN GREECE): PALAEOGEOGRAPHIC AND PALAEOCLIMATIC IMPLICATION

The Triassic is considered a crucial interval because during that time huge areas in our planet suffered an intense, long lasting, period of aridity, which favored the formation of worldwide evaporitic bodies. During the Triassic, great volumes of evaporites were formed in the Ionian basin (Western Greece). On the surface chaotically textured gypsum, surrounded by dolomitic breccias of solution-collapse origin, appears. Sedimentological and diagenetical data proposed that these salt bodies were formed in an intertidal to supratidal environment. Although halite suggests precipitation under long-term arid conditions, clay film intercalations reveal intervals of short term humid conditions. During arid periods sabkhas prevailed and brines were of marine origin. Instead, during humid intervals brines were modified by meteoric water and stormy episodes could be responsible for the transportation of clay-sized material, from the low relief surrounding terrains, into the evaporative basin. Death and burial of cyanobactehal population during storm events could be responsible for the enrichment of clayey layers in carbonaceous material. The co-existence of halite and clays in the Ionian evaporitic sequence imposes a complicated climate, possibly periodically and seasonally controlled. The impact of the precession of the equinoxes plus the palaeogeographical position dominates the local climate. The insolation over the Triassic Ionian basin and nearby sea and land areas is a crucial factor. Climate responses to gradual insolation forcing with an ocean land atmosphere feedback mechanism. The desert / monsoonal dominated climatic model seems to be most proper for the explanation of the existing lithologigal record

Genome sequences of two pseudorabies virus strains isolated in Greece

Pseudorabies virus (species Suid herpesvirus 1) belongs to the genus Varicellovirus, subfamily Alphaherpesvirinae, family Herpesviridae, and is the causative agent of an acute and frequently fatal disease that affects mainly pigs. Here, we report the genome sequences of two strains of this virus isolated in Greece in 2010

Alcohol gel ingestion amongst homeless Eastern and Central Europeans in London: assessing the effects on cognitive functioning and psychological health

Background: Intentional consumption of alcohol based hand gels has been reported especially amongst non-UK national, alcohol dependent, homeless individuals in London. Whilst alcohol misuse is known to be associated with impaired cognitive functioning and mental health problems, the effects of additional ingestion of alcohol gel are unknown. Objectives: To explore cognitive and psychological functioning in users who intentionally ingest alcohol gel compared with ethyl-alcohol only misusers and controls. Methods: Male, Central and Eastern European alcohol only misusers, (n=14; mean age 39 years), alcohol gel users (n=14; mean age 43 years) and controls (n=12; mean age 31 years) were recruited from a London Homeless Service during 2013/14. Alcohol misusers, alcohol gel users and controls were compared on the Forwards and Backwards Digit Span Test; Block Design test; Retrospective and Prospective Memory Questionnaire (PRMQ) and the Hospital and Anxiety Depression Scale (HADS). Results: Alcohol gel users performed significantly worse on the Block Design task (p<0.01) and PRMQ (p<0.01) relative to both alcohol only and control groups, and significantly worse on the digit span relative to controls (p=0.01). Both alcohol misusing groups scored comparatively on digit span backwards (p<0.01), with both groups performing significantly worse than controls. The alcohol gel group reported significantly higher levels of anxiety relative to controls (p=0.02). Conclusions: Whilst there could be constitutional differences between alcohol misusers who additionally abuse alcohol gel, the findings suggest that alcohol gel ingestion may have a greater impact on psychological functioning than traditional alcohol misuse

The globalization of corporate control

The internationalization of corporate control is a complex and poorly understood aspect of globalization, as it is challenging to trace controlling shareholders due to often opaque structures of ownership. We identify controlling shareholders for 22,000 listed firms to study the globalization of control. The network of international control appears very sparse, with strong home bias. A baseline gravity structure works well, as bilateral links are more potent for populous, affluent, and proximate countries. Institutions and tax haven status at source and destination play a modest role. Legal similarities, economic policy coordination, and cultural, linguistic, and historical ties play a non-negligible role telling of asset market and informational frictions; policy and legal similarities matter for financial institutions and banks, while informational/cultural barriers for individuals/families. International diversification motives play no major role. The results have implications for theoretical works on the internationalization of corporate control markets