L'importanza dell'accuratezza dei dati nei sistemi informativi aziendali: il caso "Esanastri srl"

Il presente lavoro si pone come obiettivo quello di passare in rassegna le principali caratteristiche dei sistemi informativi aziendali, con particolare riferimento ai sistemi ERP, mettendo in evidenza i vantaggi derivanti dall’avere a disposizione dati accurati a supporto delle decisioni. Il tutto verrà poi ricollegato alla mia personale esperienza presso l’azienda "Esanastri srl", dove ho avuto modo di occuparmi dell'accuratezza dei dati presenti a sistema, focalizzandomi sulla gestione del magazzino. Il Capitolo 1 fornirà una panoramica sui sistemi informativi aziendali, andando ad evidenziarne le principali caratteristiche e l’evoluzione che essi hanno subito nel corso degli anni. Il Capitolo 2 si focalizzerà invece sui sistemi ERP, ovvero sistemi informativi integrati, andando ad individuare cosa li differenzia dai sistemi informativi meno moderni, quali sono i requisiti e le problematiche che si possono incontrare durante la loro implementazione, e quali sono i potenziali rischi che ne derivano. Il Capitolo 3 sarà incentrato sul tema della qualità dei dati, ed in particolare sull’aspetto dell’accuratezza. Verranno forniti esempi dei costi derivanti dall’inaccuratezza dei dati, i principali vantaggi conseguibili tramite l’aumento dell’accuratezza, e come sostenere la qualità dei dati nel lungo periodo. Infine, nel Capitolo 4 verrà esaminata la situazione del sistema informativo di Esanastri, con particolare riferimento alla gestione del magazzino. Si andranno ad evidenziare i problemi riscontrati inizialmente, per poi descrivere le attività correttive intraprese, tirando infine un bilancio dei risultati conseguiti e delle prospettive future.

Effect of randomizers on the power spectrum excess of space telemetry signals

none6siThis paper presents a thorough analysis of the spectral characteristics of space telemetry signals when randomizers are used to counter the power excess, that is, the increase of the power spectrum in some measurement bandwidths with respect to the transmission of an ideal random signal. We show that a long randomizer actually improves the spectral characteristics but is not able to solve some critical problems appearing when all-zero frames or almost constant data are transmitted. Suitable solutions are proposed to face these cases, ensuring a small power excess in all possible operation conditions. The impact of high-order modulations and error correcting codes is also investigated.openMassimo Battaglioni, Marco Baldi, Franco Chiaraluce, Roberto Garello, Enrico Vassallo, Gian Paolo CalzolariBattaglioni, Massimo; Baldi, Marco; Chiaraluce, Franco; Garello, Roberto; Vassallo, Enrico; Paolo Calzolari, Gia

Combinando revisión bibliográfica, mapas acústicos y observaciones in situ: sinopsis de las formaciones coralígenas en Liguria (NO del mar Mediterráneo)

A review and update of the existing knowledge on the coralligenous assemblages of Liguria (NW Italy) was conducted as an essential step towards management measures for their conservation according to the EU Marine Strategy Framework Directive. By combining a literature review, acoustic mapping and in situ observations on a geographic information systems platform, we were able to assess the distribution and heterogeneity of coralligenous assemblages and the main pressures affecting them. The reliability of the literature was previously estimated using a dependability index. The coralligenous assemblages cover an area of 130.9 ha and range from 10 to 113 m depth. Twelve different biological facies (five of them not included in the EUNIS list) were identified and four main geomorphotypes (plungingcliffs, paleocliffs, rockfalls and shoals) were recognized. Incident light values influenced the distribution of four facies in Portofino promontory. Pressures were found on 33% of the coralligenous assemblages investigated, mainly due to fishing activities, mass mortality events, invasive species and occasional mucilaginous events. Our results showed a high spatial, geomorphological and biological heterogeneity of coralligenous assemblages in Liguria.Una revisión y actualización del conocimiento existente sobre las formaciones coralígenas en Liguria (NO de Italia) ha sido implementado como paso esencial con vistas a las medidas de gestión para su conservación de acuerdo con la Directiva Marco sobre la Estrategia Marina. Combinando en plataforma SIG revisión bibliográfica, mapas acústicos y observaciones in situ hemos sido capaces de determinar la distribución de las formaciones coralígenas, su heterogeneidad y sus principales presiones. La fiabilidad de la bibliografía fue estimada a través del índice de confianza (DI). Las formaciones coralígenas cubren un área de 130.9 ha en un rango de profundidad que va desde los 10 m a los 113 m. 12 facies biológicas diferentes (5 de ellas no incluidas en la lista EUNIS) fueron identificadas y 4 geomorfotipos principales (acantilado actual, paleoacantilado, cúmulo de rocas y bajos) fueron reconocidos. Los valores de luz incidente influenciaron la distribución de 4 facies en el promontorio de Portofino. Fueron encontradas presiones en el 33% de las formaciones coralígenas inves-tigadas, principalmente debidas a actividades de pesca, episodios de muerte masiva, especies invasoras y proliferación de algas mucilaginosas. Nuestros resultados mostraron una elevada heterogeneidad espacial, geomorfológica y biológica de las formaciones coralígenas en Liguria

Liposome-Mediated Inhibition of Inflammation by Hydroxycitrate

Hydroxycitrate (HCA), a main organic acid component of the fruit rind of Garcinia cambogia, is a natural citrate analog that can inhibit the ATP citrate lyase (ACLY) enzyme with a consequent reduction of inflammatory mediators (i.e., nitric oxide (NO), reactive oxygen species (ROS), and prostaglandin E2 (PGE2)) levels. Therefore, HCA has been proposed as a novel means to prevent, treat, and ameliorate conditions involving inflammation. However, HCA presents a low membrane permeability, and a large quantity is required to have a biological effect. To overcome this problem, HCA was formulated in liposomes in this work, and the enhancement of HCA cell availability along with the reduction in the amount required to downregulate NO, ROS, and PGE2 in macrophages were assessed. The liposomes were small in size (~60 nm), monodispersed, negatively charged (−50 mV), and stable on storage. The in vitro results showed that the liposomal encapsulation increased by approximately 4 times the intracellular accumulation of HCA in macrophages, and reduced by 10 times the amount of HCA required to abolish LPS-induced NO, ROS, and PGE2 increase. This suggests that liposomal HCA can be exploited to target the citrate pathway involved in inflammatory processes

Shallow subsurface geology and seismic microzonation in a deep continental basin. The Avezzano Town, Fucino basin (central Italy)

We present detailed geological investigations aimed at the reconstruction of the shallow subsurface geology, and associated local seismic hazard, of the Avezzano town in the Quaternary Fucino basin (central Apennines). This work shows a basic (Level 1) seismic microzonation (SM) of the Avezzano town, focusing the attention on geologic constraints. We also discuss some methodological procedures of SM. Level 1 SM involves a reconstruction of the subsurface geological model achieved by a multidisciplinary approach synthesized in two main thematic maps and geologic sections. The first map, containing essential geologic information, is formed by overlapping layers (geological units, litho-technical units, and geomorphological/structural features). The second map is a summary map, easily accessible to non-geologist earthquake scientists/technicians, which synthesizes surface geology, subsurface data and resonance frequencies into homogeneous microzones. The two maps are tools for land and urban planning. The Avezzano area provides a case study of shallow subsurface geology and site effects in a deep continental basin environment, and is of potential interest for similar geologic contexts worldwide. Within the investigated area, almost all the possible earthquake-induced effects can occur, such as (a) stratigraphic amplifications in a wide range of resonance frequencies (from 0.4 to > 10 Hz); (b) liquefaction; (c) coseismic surface faulting; (d) basin-edge effects; and (e) slope instability

Insomnia and Migraine: A Missed Call?

: Migraine is one of the most prevalent and disabling neurological conditions, presenting episodes of throbbing headache that limit activities of daily living. Several factors may influence migraine frequency, such as lifestyle or alcohol consumption. Among the most recognised ones, sleep plays a biunivocal role, since poor sleep quality may worsen migraine frequency, and a high migraine frequency may affect sleep quality. In this paper, the authors evaluate the relationship between migraine and insomnia by exploring a cohort of patients affected by episodic or chronic migraine. To do so, a phone interview was performed, asking patients about their migraine frequency and mean pain intensity, in addition to the questions of the Insomnia Severity Index. The last one explores several symptoms impairing sleep that focus on insomnia. Patients complaining of insomnia showed an increased migraine frequency, and a weak but significant correlation was found between headache days per month and insomnia scores. Such results were particularly evident in patients affected by chronic migraine. Such results suggest how insomnia, in the presented data, seems to be associated with migraine frequency but not with pain intensity

Immunometabolism Modulation by Extracts from Pistachio Stalks Formulated in Phospholipid Vesicles

Several studies have demonstrated the effectiveness of plant extracts against various diseases, especially skin disorders; namely, they exhibit overall protective effects. The Pistachio (Pistacia vera L.) is known for having bioactive compounds that can effectively contribute to a person’s healthy status. However, these benefits may be limited by the toxicity and low bioavailability often inherent in bioactive compounds. To overcome these problems, delivery systems, such as phospholipid vesicles, can be employed. In this study, an essential oil and a hydrolate were produced from P. vera stalks, which are usually discarded as waste. The extracts were characterized by liquid and gas chromatography coupled with mass spectrometry and formulated in phospholipid vesicles intended for skin application. Liposomes and transfersomes showed small size (<100 nm), negative charge (approximately −15 mV), and a longer storage stability for the latter. The entrapment efficiency was determined via the quantification of the major compounds identified in the extracts and was >80%. The immune-modulating activity of the extracts was assayed in macrophage cell cultures. Most interestingly, the formulation in transfersomes abolished the cytotoxicity of the essential oil while increasing its ability to inhibit inflammatory mediators via the immunometabolic citrate pathway

Seamounts as hot-spots of large pelagic aggregations

The distribution of four top predators in the Tyrrhenian Sea, a sub-basin of the Mediterranean Sea, was investigated by means of random forest regression considering depth, distance from the coast, seafloor slope, and distance from seamounts as habitat descriptors on a 2x2–nautical mile regular grid. RF results are processed to estimate variable importance and model performance. Random forest architecture reached optimal sensitivity and specificity, thus providing a consistent support tool for identifying suitable habitats. The considered species are characterized as having patched suitable habitats with a number of hot-spot areas where the different species' habitats overlap. These hot-spot areas' locations correspond to those of specific seamounts identifying the attraction effect of these topographic structures. The mean features typifying the most attractive seamounts are investigated and found to be shallow peak and base depths but wide base area and high relative elevation