1,183 research outputs found
Application of Deep Learning Long Short-Term Memory in Energy Demand Forecasting
The smart metering infrastructure has changed how electricity is measured in
both residential and industrial application. The large amount of data collected
by smart meter per day provides a huge potential for analytics to support the
operation of a smart grid, an example of which is energy demand forecasting.
Short term energy forecasting can be used by utilities to assess if any
forecasted peak energy demand would have an adverse effect on the power system
transmission and distribution infrastructure. It can also help in load
scheduling and demand side management. Many techniques have been proposed to
forecast time series including Support Vector Machine, Artificial Neural
Network and Deep Learning. In this work we use Long Short Term Memory
architecture to forecast 3-day ahead energy demand across each month in the
year. The results show that 3-day ahead demand can be accurately forecasted
with a Mean Absolute Percentage Error of 3.15%. In addition to that, the paper
proposes way to quantify the time as a feature to be used in the training phase
which is shown to affect the network performance
Spin Fluctuation-Induced Superconductivity in Organic Compounds
Spin fluctuation-induced superconductivity in two-dimensional organic
compounds such as \kappa-(ET)_2-X is investigated by using a simplified dimer
Hubbard model with right-angled isosceles triangular lattice (transfer matrices
-\tau, -\tau^\prime). The dynamical susceptiblity and the self-energy are
calculated self-consistently within the fluctuation exchange approximation and
the value for T_c as obtained by solving the linearized Eliashberg-type
equations is in good agreement with experiment. The pairing symmetry is of
d_{x^2-y^2} type. The calculated (U/\tau)-dependence of T_c compares
qualitatively well with the observed pressure dependence of T_c. Varying the
value for \tau^\prime/\tau from 0 to 1 we interpolate between the square
lattice and the regular triangular lattice and find firstly that values of T_c
for \kappa-(ET)_2-X and cuprates scale well and secondly that T_c tends to
decrease with increasing \tau^\prime/\tau and no superconductivity is found for
\tau^\prime/\tau=1, the regular triangular lattice.Comment: 4 pages, 6 eps figures, uses jpsj.st
Nitrogen-Functionalized Graphene Nanoflakes (GNFs:N): Tunable Photoluminescence and Electronic Structures
This study investigates the strong photoluminescence (PL) and X-ray excited
optical luminescence observed in nitrogen-functionalized 2D graphene nanoflakes
(GNFs:N), which arise from the significantly enhanced density of states in the
region of {\pi} states and the gap between {\pi} and {\pi}* states. The
increase in the number of the sp2 clusters in the form of pyridine-like N-C,
graphite-N-like, and the C=O bonding and the resonant energy transfer from the
N and O atoms to the sp2 clusters were found to be responsible for the blue
shift and the enhancement of the main PL emission feature. The enhanced PL is
strongly related to the induced changes of the electronic structures and
bonding properties, which were revealed by the X-ray absorption near-edge
structure, X-ray emission spectroscopy, and resonance inelastic X-ray
scattering. The study demonstrates that PL emission can be tailored through
appropriate tuning of the nitrogen and oxygen contents in GNFs and pave the way
for new optoelectronic devices.Comment: 8 pages, 6 figures (including toc figure
Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
Somatically acquired mutations in the epidermal growth factor receptor (EGFR) gene in lung cancer are associated with significant clinical responses to gefitinib, a tyrosine kinase inhibitor that targets EGFR. We screened the EGFR in 469 resected tumours of patients with lung cancer, which included 322 adenocarcinomas, 102 squamous cell carcinomas, 27 large cell carcinomas, 13 small cell carcinomas, and five other cell types. PCR with a specific condition was performed to identify any deletion in exon 19, while mutant-allele-specific amplification was performed to identify a mutation in codon 858 of exon 21. EGFR mutations were found in 136 cases (42.2%) with adenocarcinoma, in one case with large cell carcinoma, and in one case with pleomorphic carcinoma. An in-frame deletion in exon 19 was found in 62 cases while an L858R mutation was found in 77 cases. In the 322 cases with adenocarcinoma, these mutations were more frequently found in women than in men (P=0.0004), in well differentiated tumours than in poorly differentiated tumours (P=0.0014), and in patients who were never smokers than in patients who were current/former smokers (P<0.0001). The mutation was more frequently observed in patients who smoked ⩽20 pack-year, and in patients who quit at least 20 years before the date of diagnosis for lung cancer. The K-ras mutations were more frequently found in smokers than in never smokers, and in high-dose smokers than in low-dose smokers. In conclusion, the mutations within the tyrosine kinase domain of EGFR were found to specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
Electrodynamics of Media
Contains reports on six research projects.Joint Services Electronics Program (Contract DAABO7-71-C-0300)U. S. Army Research Office - Durham (Contract DAHC04-72-C-0044)National Science Foundation (Grant GK-31012X), Cornell Universit
Effect of local atomic and electronic structures on thermoelectric properties of chemically substituted CoSi
[[abstract]]We report the effects of Ge partial substitution for Si on local atomic and electronic structures of thermoelectric materials in binary compound cobalt monosilicides (CoSi1−xGex: 0 ≤ x ≤ 0.15). Correlations between local atomic/electronic structure and thermoelectric properties are investigated by means of X-ray absorption spectroscopy. The spectroscopic results indicate
that as Ge is partially substituted onto Si sites at x ≤ 0.05, Co in CoSi1−xGex gains a certain amount of charge in its 3d orbitals. Contrarily, upon further replacing Si with Ge at x ≥ 0.05, the Co 3d orbitals start to lose some of their charge. Notably, thermopower is strongly correlated with charge redistribution in the Co 3d orbital, and the observed charge transfer between Ge and Co is responsible for the variation of Co 3d occupancy number. In addition to Seebeck coefficient, which can be modified by tailoring the Co 3d states, local lattice disorder may also be beneficial in enhancing the thermoelectric properties. Extended X-ray absorption fine structure spectrum results further demonstrate that the lattice phonons can be enhanced by Ge doping, which results in the formation of the disordered Co-Co pair. Improvements in the thermoelectric properties are interpreted based on the variation of local atomic and electronic structure induced by lattice distortion through chemical substitution.[[incitationindex]]SCI[[booktype]]紙本[[booktype]]電子
A model for collisions in granular gases
We propose a model for collisions between particles of a granular material
and calculate the restitution coefficients for the normal and tangential motion
as functions of the impact velocity from considerations of dissipative
viscoelastic collisions. Existing models of impact with dissipation as well as
the classical Hertz impact theory are included in the present model as special
cases. We find that the type of collision (smooth, reflecting or sticky) is
determined by the impact velocity and by the surface properties of the
colliding grains. We observe a rather nontrivial dependence of the tangential
restitution coefficient on the impact velocity.Comment: 11 pages, 2 figure
s-wave superconductivity from antiferromagnetic spin-fluctuation model for bilayer materials
It is usually believed that the spin-fluctuation mechanism for
high-temperature superconductivity results in d-wave pairing, and that it is
destructive for the conventional phonon-mediated pairing. We show that in
bilayer materials, due to nearly perfect antiferromagnetic spin correlations
between the planes, the stronger instability is with respect to a
superconducting state whose order parameters in the even and odd plane-bands
have opposite signs, while having both two-dimensional -symmetry. The
interaction of electrons with Raman- (infrared-) active phonons enhances
(suppresses) the instability.Comment: Revtex, 3 figure
Ultra-High Energy Cosmic Ray production in the polar cap regions of black hole magnetospheres
We develop a model of ultra-high energy cosmic ray (UHECR) production via
acceleration in a rotation-induced electric field in vacuum gaps in the
magnetospheres of supermassive black holes (BH). We show that if the poloidal
magnetic field near the BH horizon is misaligned with the BH rotation axis,
charged particles, which initially spiral into the BH hole along the equatorial
plane, penetrate into the regions above the BH "polar caps" and are ejected
with high energies to infinity. We show that in such a model acceleration of
protons near a BH of typical mass 3e8 solar masses is possible only if the
magnetic field is almost aligned with the BH rotation axis. We find that the
power of anisotropic electromagnetic emission from an UHECR source near a
supermassive BH should be at least 10-100 times larger then UHECR power of the
source. This implies that if the number of UHECR sources within the 100 Mpc
sphere is ~100, the power of electromagnetic emission which accompanies proton
acceleration in each source, erg/s, is comparable to the typical
luminosities of active galactic nuclei (AGN) in the local Universe. We also
explore the acceleration of heavy nuclei, for which the constraints on the
electromagnetic luminosity and on the alignment of magnetic field in the gap
are relaxed
Mutational Analysis of EGFR and Related Signaling Pathway Genes in Lung Adenocarcinomas Identifies a Novel Somatic Kinase Domain Mutation in FGFR4
BACKGROUND: Fifty percent of lung adenocarcinomas harbor somatic mutations in six genes that encode proteins in the EGFR signaling pathway, i.e., EGFR, HER2/ERBB2, HER4/ERBB4, PIK3CA, BRAF, and KRAS. We performed mutational profiling of a large cohort of lung adenocarcinomas to uncover other potential somatic mutations in genes of this signaling pathway that could contribute to lung tumorigenesis. METHODOLOGY/PRINCIPAL FINDINGS: We analyzed genomic DNA from a total of 261 resected, clinically annotated non-small cell lung cancer (NSCLC) specimens. The coding sequences of 39 genes were screened for somatic mutations via high-throughput dideoxynucleotide sequencing of PCR-amplified gene products. Mutations were considered to be somatic only if they were found in an independent tumor-derived PCR product but not in matched normal tissue. Sequencing of 9MB of tumor sequence identified 239 putative genetic variants. We further examined 22 variants found in RAS family genes and 135 variants localized to exons encoding the kinase domain of respective proteins. We identified a total of 37 non-synonymous somatic mutations; 36 were found collectively in EGFR, KRAS, BRAF, and PIK3CA. One somatic mutation was a previously unreported mutation in the kinase domain (exon 16) of FGFR4 (Glu681Lys), identified in 1 of 158 tumors. The FGFR4 mutation is analogous to a reported tumor-specific somatic mutation in ERBB2 and is located in the same exon as a previously reported kinase domain mutation in FGFR4 (Pro712Thr) in a lung adenocarcinoma cell line. CONCLUSIONS/SIGNIFICANCE: This study is one of the first comprehensive mutational analyses of major genes in a specific signaling pathway in a sizeable cohort of lung adenocarcinomas. Our results suggest the majority of gain-of-function mutations within kinase genes in the EGFR signaling pathway have already been identified. Our findings also implicate FGFR4 in the pathogenesis of a subset of lung adenocarcinomas
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