909 research outputs found

    Investigations of beryllium anodes in nonaqueous electrolyte solutions Final report

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    Compatible electrolyte for beryllium anode in electrochemical cel

    Nature of the surface compounds and reactions observed on graphite electrodes

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    The nature and composition of the surface of pyrolytic graphite and the consequent possible effects, when the material is used as an electrode, are considered on the basis of the structure of the graphite and of the handling and/or treatment to which the electrodes may have been exposed. Because of the relatively limited studies on pyrolytic graphite, certain aspects of the behavior of other types of graphite and of carbon are discussed owing to their probable relation to the behavior of pyrolytic graphite. An appreciation of the constitution of graphite electrodes in terms of surface compounds and of the possible interaction of these compounds with solution species or their reaction products, when the electrodes are used in electrolytic processes, is essential for their optimum utilization. The main areas surveyed are the structure of pyrolytic graphite as related to electrode usage, types of possible compound formation, electrolytic behavior of graphite electrodes, and formation of carbon-oxygen and related organic surface compounds with the resulting influence on adsorption and other phenomena.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22000/1/0000413.pd

    Identification of women with early breast cancer by analysis of p43-positive lymphocytes

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    Regular screening mammographies and increasing knowledge of high-risk groups have resulted in an improvement in the rate of detection of smaller malignant lesions. However, uncertain minimal mammographic features frequently require further costly and often uncomfortable investigation, including repeat radiological controls or surgical procedures, before cancerous lesions can be identified. Placental isoferritin (p43), a protein with immunosuppressive effects, has been detected on the surface of lymphocytes taken from peripheral blood in patients with breast cancer. In this study we evaluated the sensitivity and specificity of the expression of p43-positive lymphocytes as a marker in early stage breast cancer and also investigated its expression on T-cell subpopulations. The presence of p43-positive lymphocytes was investigated using the monoclonal antibody CM-H-9 and flow cytometry in 76 women with controversial, non-palpable mammographic findings who were undergoing surgical biopsy. Patients with early breast cancer (n = 48) had significantly higher p43-positive cell values (median 3.83%, range 0.98-19.4) than patients with benign lumps (n = 28, median 1.43%, range 0.17-3.7) or controls (n = 22, median 1.3%, range 0.4-1.87) (P \u3c 0.0001). At a cut-off level of 2% p43-positive cells a sensitivity of 91.7% and a specificity of 89.3% for detection of breast cancer could be reached. While the median ratio of total CD4+/CD8+ cells was 2.6, a ratio of 1.3 was found for the p43-positive subpopulation (P \u3c 0.001), thus indicating a significant link between p43 and CD8+ cells. The determination of p43-positive lymphocytes in peripheral blood could serve as an additional diagnostic tool in patients with controversial mammographic findings and could also reduce the need for cost-intensive and often uncomfortable management of these patients

    Bubble Growth in Superfluid 3-He: The Dynamics of the Curved A-B Interface

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    We study the hydrodynamics of the A-B interface with finite curvature. The interface tension is shown to enhance both the transition velocity and the amplitudes of second sound. In addition, the magnetic signals emitted by the growing bubble are calculated, and the interaction between many growing bubbles is considered.Comment: 20 pages, 3 figures, LaTeX, ITP-UH 11/9

    Determination of the branching ratios Γ(KL3π0)/Γ(KLπ+ππ0)\Gamma (K_L \to 3 \pi^0) / \Gamma (K_L \to \pi^+ \pi^- \pi^0) and Γ(KL3π0)/Γ(KLπeν)\Gamma (K_L \to 3 \pi^0) / \Gamma (K_L \to \pi e \nu )

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    Improved branching ratios were measured for the KL3π0K_L \to 3 \pi^0 decay in a neutral beam at the CERN SPS with the NA31 detector: Γ(KL3π0)/Γ(KLπ+ππ0)=1.611±0.037\Gamma (K_L \to 3 \pi^0) / \Gamma (K_L \to \pi^+ \pi^- \pi^0) = 1.611 \pm 0.037 and Γ(KL3π0)/Γ(KLπeν)=0.545±0.010\Gamma (K_L \to 3 \pi^0) / \Gamma (K_L \to \pi e \nu ) = 0.545 \pm 0.010. From the first number an upper limit for ΔI=5/2\Delta I =5/2 and ΔI=7/2\Delta I = 7/2 transitions in neutral kaon decay is derived. Using older results for the Ke3/Kμ\mu 3 fraction, the 3π0\pi^0 branching ratio is found to be Γ(KL3π0)/Γtot=(0.211±0.003)\Gamma (K_L \to 3 \pi^0 )/ \Gamma_{tot} = (0.211 \pm 0.003), about a factor three more precise than from previous experiments

    Postoperative irradiation for squamous cell carcinoma of head and neck: Retrospective comparison of accelerated radiochemotherapy and standard radiotherapy

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    Background: Comparison of accelerated radiochemotherapy (aRCT) and standard radiotherapy (sRT) in postoperative treatment after macroscopically complete resection of squamous cell cancers of head and neck. Material and Methods: 229 patients treated within the same period had either (no randomization) postoperative radiotherapy with conventional fractionation (60-70 Gy, 2.0 Gy per day) or received 2 fractions of 2.1 Gy per day, 8 times\textbackslash{}week, up to a total dose of 56.7 Gy with a treatment split after 2 weeks and simultaneous low dose cisplatin or carboplatin on treatment clays (cumulative dose >66 mg/m(2) or 550 mg/m(2) in 83% of patients). Results: 65 patients completed their course of twice-daily irradiations within a maximum of 35 days and therefore had aRCT; their 3-year locoregional tumor control (Kaplan-Meier estimate) was 86%, whereas that of 42 patients with prolonged twice-daily radiochemotherapy was 65% (p=0.0509). After sRT, i.e. 1 fraction daily and treatment time up to 45 days, locoregional tumor control was 67%, this result being significantly inferior to that after aRCT (p=0.0282). In multivariate analysis, pN stage, tumor site oral cavity/floor of mouth, high/moderate differentiation of squamous cell carcinoma and conventional surgery (versus CO2-laser surgery) were significantly predictive of locoregional failure. Whereas nodal status, the strongest prognostic factor, was evenly distributed among aRCT and sRT patients, there was a misbalance of 3 risk factors favoring the aRCT collective. Superior tumor control after aRCT was confirmed unilaterally for nearly each subgroup (significant for recurrent tumors, close margins, pN1/2a-b). For pN2c/pN3 nodal stage, the results after aRCT were by tendency worse than after sRT, possibly due to a particularly long interval between surgery and start of radio(chemo)therapy for the patients with aRCT (mean 58.0 days vs. 43.8 days, p=0.037). Among the total of patients the 3-year hazard for late toxicity Ill-IV was 31% after twice-daily treatment and 17% after conventionally fractionated radiotherapy (p=0.083). Conclusions:This retrospective analysis provides some evidence that accelerated radiotherapy with simultaneous chemotherapy is more potent than standard radiotherapy. However, as multivariate analysis misses significance and the influence of misbalance of some prognostic factors among aRCT and sRT patients remains unclear, only a randomized trial with stratification according to risk factors as well as a defined interval between surgery and initiation of RT can provide more evidence

    Herniation Pits in Human Mummies: A CT Investigation in the Capuchin Catacombs of Palermo, Sicily

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    Herniation pits (HPs) of the femoral neck were first described in a radiological publication in 1982 as round to oval radiolucencies in the proximal superior quadrant of the femoral neck on anteroposterior radiographs of adults. In following early clinical publications, HPs were generally recognized as an incidental finding. In contrast, in current clinical literature they are mentioned in the context of femoroacetabular impingement (FAI) of the hip joint, which is known to cause osteoarthritis (OA). The significance of HPs in chronic skeletal disorders such as OA is still unclear, but they are discussed as a possible radiological indicator for FAI in a large part of clinical studies

    Measurement of the branching ratio of the decay Ξ0Σ+μνˉμ\Xi^{0}\rightarrow \Sigma^{+} \mu^{-} \bar{\nu}_{\mu}

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    From the 2002 data taking with a neutral kaon beam extracted from the CERN-SPS, the NA48/1 experiment observed 97 Ξ0Σ+μνˉμ\Xi^{0}\rightarrow \Sigma^{+} \mu^{-} \bar{\nu}_{\mu} candidates with a background contamination of 30.8±4.230.8 \pm 4.2 events. From this sample, the BR(Ξ0Σ+μνˉμ\Xi^{0}\rightarrow \Sigma^{+} \mu^{-} \bar{\nu}_{\mu}) is measured to be (2.17±0.32stat±0.17syst)×106(2.17 \pm 0.32_{\mathrm{stat}}\pm 0.17_{\mathrm{syst}})\times10^{-6}

    Measurement of the branching ratios of the decays Xi0 --> Sigma+ e- nubar and anti-Xi0 --> anti-Sigma+ e+ nu

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    From 56 days of data taking in 2002, the NA48/1 experiment observed 6316 Xi0 --> Sigma+ e- nubar candidates (with the subsequent Sigma+ --> p pi0 decay) and 555 anti-Xi0 --> anti-Sigma+ e+ nu candidates with background contamination of 215+-44 and 136+-8 events, respectively. From these samples, the branching ratios BR(Xi0 --> Sigma+ e- nubar)= (2.51+-0.03stat+-0.09syst)E(-4) and BR(anti-Xi0 --> anti-Sigma+ e+ nu)= (2.55+-0.14stat+-0.10syst)E(-4) were measured allowing the determination of the CKM matrix element |Vus| = 0.209+0.023-0.028. Using the Particle Data Group average for |Vus| obtained in semileptonic kaon decays, we measured the ratio g1/f1 = 1.20+-0.05 of the axial-vector to vector form factors.Comment: 16 pages, 11 figures Submitted to Phys.Lett.

    Observation of the rare decay K_S -> pi^0mu^+mu^-

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    A search for the decay K_S -> pi^0mu^+mu^- has been made by the NA48/1 Collaboration at the CERN SPS accelerator. The data were collected during 2002 with a high-intensity K_S beam. Six events were found with a background expectation of 0.22^+0.18_-0.11 event. Using a vector matrix element and unit form factor, the measured branching ratio is B(K_S -> pi^0mu^+mu^-)=[2.9^+1.5_-1.2(stat)+/-0.2(syst)]x10^{-9}.Comment: 19 pages, 8 figures, 4 tables. To be published in Physics Letters
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