A novel fluorescent probe for NAD-consuming enzymes

A novel, fluorescent NAD derivative is processed as substrate by three different NAD-consuming enzymes. The new probe has been used to monitor enzymatic activity in a continuous format by changes in fluorescence and, in one case, to directly visualize alternative reaction pathways

Graviton-Scalar Interaction in the PP-Wave Background

We compute the graviton two scalar off-shell interaction vertex at tree level in Type IIB superstring theory on the pp-wave background using the light-cone string field theory formalism. We then show that the tree level vertex vanishes when all particles are on-shell and conservation of p_{+} and p_{-} are imposed. We reinforce our claim by calculating the same vertex starting from the corresponding SUGRA action expanded around the pp-wave background in the light-cone gauge.Comment: 26 pages, harvmac One reference added. A few comments changed in the introduction. The "cyclic perms." term removed from some equations as unnecessary and equations (2.38) and (3.19) are corrected accordingl

Superstrings and D-branes in A Plane Wave

We carefully analyze the supersymmetry algebra of closed strings and open strings in a type IIB plane wave background. We use eight component chiral spinors, SO(8) Majorana-Weyl spinors, in light-cone gauge to provide a useful basis of string field theory calculation in the plane wave. We consider the two classes of D-branes, $D_\pm$-branes, and give a worldsheet derivation of conserved supercurrents for all half BPS D-branes preserving 16 supersymmetries in the type IIB plane wave background. We exhaustively provide the supersymmetry algebra of the half BPS branes as well. We also point out that the supersymmetry algebra distinguishes the two SO(4) directions with relative sign which is consistent with the Z_2 symmetry of the string action.Comment: v4: 28 pages, Latex, Worldsheet derivation of conserved supercurrents for all half BPS D-branes newly added, improved presentation and typo

Non-perturbative contributions to the plane-wave string mass matrix

D-instanton contributions to the mass matrix of arbitrary excited string states of type IIB string theory in the maximally supersymmetric plane-wave background are calculated to leading order in the string coupling using a supersymmetric light-cone boundary state formalism. The explicit non-perturbative dependence of the mass matrix on the complex string coupling, the plane-wave mass parameter and the mode numbers of the excited states is determined.Comment: 25 pages, 1 figure. v3: corrected minor typos, added referenc

D-branes in PP-wave light cone string field theory

The cubic interaction vertex and the dynamical supercharges are constructed for open strings ending on D7-branes, in light-cone superstring field theory in PP-wave background. In this context, we write down the symmetry generators in terms of the relevant group structure: SU(2) x SU(2) x SO(2) x SO(2), originating from the eight transverse directions in the PP-wave background and use the expressions to explicitly construct the vertex at the level of stringy zero modes. The results are further generalized to include all the stringy excitations as well.Comment: 30 pages, correction in eqn. (4.28), few equations (appendix), Comments (p.17-18) and a reference (no. 58) added, typo is corrected in eqn. (4.5