Correlation of Griva Parinaah (GP) in Anguli Praman and BMI in Medovriddhi (Obesity) w.s.r. to Cardiovascular Risk

The prevalence of overweight and obesity in India is increasing faster than the world average Medovriddhi (obesity) shows the symptoms as increased size of buttocks, breast and abdomen, Shwasa (breathlessness) after slight movement also. Acharya Bhavprakash added one more symptom the oversize of the neck (Griva). Acharya Sushruta mentioned the Griva measurement should be 20 Angul for both males and females with their fingers (self-finger unit). In modern science, body mass index (BMI) is used to find out obesity. Obesity is the foremost cause of cardiovascular diseases. BMI is the generalized metric way but Grivaparinaah in Swangulpramaan is a personalized quantifying anthropometric measurement. Individuals of Medovriddhi having an age group of 20 to 70 years were selected. So, intending to the height the importance of Grivaparinaah described in Medodhatu Vruddhi correlation study having been carried out. A positive correlation was found in GP with BMI in both genders having r-value of 0.3533 (p<0.05) for males and 0.3137 (p<0.05) for females. Using ROC curve analysis GP is >21.63 Angul for males and females were determined to be the best cut-off level for identifying a subject with BMI as cardiovascular risk

A Biochemical Approach to Understand the Concept of Snigdha Guna of Ghee and Ruksha Guna of Terminalia arjuna on Behaviour of 3T3-L1 Cell Line with Respect to Adipocytic and Anti-Adipocytic Activity : In Vitro

Ayurvedic medicine is a system of traditional medicine native to India. Ayurveda is based on peculiar fundamental principles like Shatpadarth, Tridosha Theory, Panchamahabhuta Theory, Prakriti, Ojas, Dhatu, Mala, Agni, Manas, and Atma etc. The concepts of Ayurveda are expressed with Gunas. The increased elements are treated by opposite Guna. In support of the above concept, an experimental study on the 3T3-L1 cell line is carried out for examine the adipocytic and anti adipocytic activity of Snigdha and Ruksha Guna respectively. The results were assessed with the help of evaluation of sublethal concentration by using XTT assay and lipid assay. The aim of basic research in Ayurveda through bioscience is to explore scientific innovation and opportunities in fundamental concept of Ayurveda. Fundamental research needs to be done to highlight the concept of gurvadi guna through the in vitro study

Concept of Dhatri (wet nurse) in perspective of Ayurveda w.r.t. Babylonian Code of Hammurabi

Ayurveda, the native healthcare system of India, is a rich resource of well-documented ancient medical knowledge. Although the roots of this knowledge date back to the Vedic and post-Vedic eras, it is generally believed that a dedicated branch for healthcare was gradually established approximately between 400 BC and 200 AD. It is well known and nature’s gift that breastfeeding is the best nutrition for human infants. There are several problems in motherhood so in such cases there is an alternative source for breastfeeding given in the code of Hammurabi and Ayurveda. But in today’s world, there are advancements in the technology through which we preserve mother's breast milk and form milk bank and formula feed for baby. But there is a lack of love, care, and nutritional values that varies in the milk bank and formula feed. Due to advancement in the technology, there is some drawback which affects the baby normal life in term of nutritional value. Anger, grief, and lack of affection, etc. cause loss of breast milk. Ayurveda has a concept of Dhatri from an ancient time in the absence of mother milk for the baby. Dhatri another mother for the baby. Hence this article reviews the concept of Dhatri (wet nurse) in perspective of Ayurveda w.r.t. Babylonian Code of Hammurabi

Data Privacy Preserving using Perturbation Technique

Data Mining mainly consist of the discovery of structures, associations and the events in the data. In order to analyze the data related to sector like healthcare, privacy of data is to be maintained. In order to maintain the privacy of data, a perturbation technique is applied on original dataset and a new dataset is formed which is different from original dataset. Data mining can be performed on this perturbed dataset for various surveys and analysis. In this paper, perturbation technique algorithm is explained step by step in order to preserve the privacy of data

Effectiveness of balance exercises in the acute post-operative phase following total hip and knee arthroplasty: A randomized clinical trial

Objectives: To determine the effectiveness of balance exercises in the acute post-operative phase following total hip arthroplasty or total knee arthroplasty. Methods: Patients who had total hip arthroplasty ( n  = 30) or total knee arthroplasty ( n  = 33) were seen in their residence 1–2 times per week for 5 weeks. At the first post-operative home visit, patients were randomly assigned to either typical (TE, n  = 33) or typical plus balance (TE + B, n  = 30) exercise groups. The TE group completed seven typical surgery-specific joint range-of-motion and muscle strengthening exercises, while the TE + B group completed the typical exercises plus three balance exercises. Patients were assessed before and 5 weeks after administering the rehabilitation program using four outcome measures: (1) the Berg Balance Scale, (2) the Timed Up and Go test, (3) the Western Ontario McMaster Universities Osteoarthritis Index, and (4) the Activities-specific Balance Confidence Scale. Results: Post-intervention scores for all four outcome measures were significantly improved ( p  < 0.01) over baseline scores. Patients who participated in the TE + B group demonstrated significantly greater improvement on the Berg Balance Scale and the Timed Up and Go tests ( p  < 0.01). Conclusion: Balance exercises added to a typical rehabilitation program resulted in significantly greater improvements in balance and functional mobility compared to typical exercises alone

Force-plate analyses of balance following a balance exercise program during acute post-operative phase in individuals with total hip and knee arthroplasty: A randomized clinical trial

Objectives: Typical rehabilitation programs following total hip arthroplasty and total knee arthroplasty include joint range of motion and muscle-strengthening exercises. Balance and balance exercises following total hip arthroplasty and total knee arthroplasty have not received much attention. The purpose of this study was to determine whether an intervention of balance exercises added to a typical rehabilitation program positively affects patients’ balance. Methods: A total of 63 patients were provided with outpatient physical therapy at their home. Patients were randomly assigned to either typical (n = 33) or balance (n = 30) exercise group. The typical group completed seven typical surgery-specific joint range of motion and muscle-strengthening exercises, while the balance group completed the typical exercises plus three balance exercises. After 5 weeks of administering the rehabilitation program, patients’ balance was assessed on a force plate using 95% ellipse area of the center of pressure amplitude. Results: Patients in the balance group demonstrated significant reduction in the 95% ellipse area for the anterior and posterior lean standing conditions (p < 0.01). Conclusion: Balance exercises added to the typical outpatient physical therapy program resulted in significantly greater improvements in balance for participants with total hip arthroplasty or total knee arthroplasty, compared to the typical exercise program alone. Physical therapists might consider the use of balance exercises to improve balance in individuals in the acute post-operative phase following total hip arthroplasty or total knee arthroplasty

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

BACKGROUND Susceptibility to asthma is influenced by genes and environment; implicated genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful in identifying subtypes of asthma and determining whether intermediate phenotypes, such as elevation of the total serum IgE level, are causally linked to disease. METHODS We carried out a genomewide association study by genotyping 10,365 persons with physician-diagnosed asthma and 16,110 unaffected persons, all of whom were matched for ancestry. We used random-effects pooled analysis to test for association in the overall study population and in subgroups of subjects with childhood-onset asthma (defined as asthma developing before 16 years of age), later-onset asthma, severe asthma, and occupational asthma. RESULTS We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P = 3x10(-9)); rs9273349 on chromosome 6, implicating HLA-DQ (P = 7x10(-14)); rs1342326 on chromosome 9, flanking IL33 (P = 9x10(-10)); rs744910 on chromosome 15 in SMAD3 (P = 4x10(-9)); and rs2284033 on chromosome 22 in IL2RB (P = 1.1x10(-8)). Association with the ORMDL3/GSDMB locus on chromosome 17q21 was specific to childhood-onset disease (rs2305480, P = 6x10(-23)). Only HLA-DR showed a significant genomewide association with the total serum IgE concentration, and loci strongly associated with IgE levels were not associated with asthma. CONCLUSIONS Asthma is genetically heterogeneous. A few common alleles are associated with disease risk at all ages. Implicated genes suggest a role for communication of epithelial damage to the adaptive immune system and activation of airway inflammation. Variants at the ORMDL3/GSDMB locus are associated only with childhood-onset disease. Elevation of total serum IgE levels has a minor role in the development of asthma

Abstracts of National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020

This book presents the abstracts of the papers presented to the Online National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020 (RDMPMC-2020) held on 26th and 27th August 2020 organized by the Department of Metallurgical and Materials Science in Association with the Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, India. Conference Title: National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020Conference Acronym: RDMPMC-2020Conference Date: 26–27 August 2020Conference Location: Online (Virtual Mode)Conference Organizer: Department of Metallurgical and Materials Engineering, National Institute of Technology JamshedpurCo-organizer: Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, IndiaConference Sponsor: TEQIP-