CARACTERIZAÇÃO DOS CASOS DE DENGUE POR LOCALIZAÇÃO NO INTERIOR DE MATO GROSSO ENTRE 2007 E 2016

Objective: to characterize the reported dengue cases according to location, in Rondonópolis, Mato Grosso, between 2007 and 2016. Method: epidemiological, ecological, quantitative study using a descriptive approach. Secondary source data including sociodemographic and clinical variables and location of dengue cases. Descriptive statistics were used and maps of the quantiles of the cases were presented, as well as the distribution by neighborhoods. Results: there were indications that, although notifications were observed over the entire area, the disease mainly proliferated in Centro, Centros A and B and Villa Aurora, considered populous neighborhoods. It was also observed that areas with greater numbers of cases were located near rivers, streams and areas of environmental protection. Conclusion: the geographic picture of dengue should warn researchers and the health management of the municipality about the behavior of the disease, aiming for efficient planning and implementation of prevention and control actions.Objetivo: Caracterizar los casos notificados de dengue según su localización en Rondonópolis, Mato Grosso, entre 2007 y 2016. Método: Estudio epidemiológico del tipo ecológico, con abordaje cualitativo y descriptivo. Datos de fuente secundaria, incluyendo variables sociodemográficas, clínicas y localización de los casos de dengue. Se aplicó estadística descriptiva, se presentaron mapas por porcentual de casos y de distribución por barrios. Resultados: Se presume que, aunque se observen notificaciones en toda la extensión territorial, proliferó principalmente en el Centro, Centros A y B y Vila Aurora, considerados barrios populosos y poblados. También se observó que las áreas con mayor número de casos están localizadas cerca de ríos, arroyos y áreas ambientales protegidas. Conclusión: El esquema geográfico del dengue debe alertar a investigadores y a la gestión sanitaria municipal sobre el comportamiento de la enfermedad, para una planificación eficiente y la ejecución de acciones de prevención y control.Objetivo: caracterizar os casos notificados de dengue de acordo com a localização, em Rondonópolis, Mato Grosso, entre 2007 e 2016. Método: estudo epidemiológico do tipo ecológico de abordagem quantitativa e descritiva. Dados de fonte secundária incluindo variáveis sociodemográficas, clínicas e localização dos casos de dengue. Foi utilizada estatística descritiva e apresentados mapas dos quantis dos casos, bem como a distribuição por bairros. Resultados: há indicativos que, embora seja observada notificação por toda extensão territorial, proliferou principalmente no Centro, Centros A e B e Vila Aurora, considerados bairros populosos e povoados. Também se observou que áreas com maior número de casos estão localizadas próximas a rios, córregos e áreas ambientais protegidas. Conclusão: o retrato geográfico da dengue deve alertar pesquisadores e a gestão de saúde do município sobre o comportamento da doença, a fim de um planejamento eficiente e execução de ações de prevenção e controle

Selenium status and cardiovascular risk factors in populations from different portuguese regions

Proceedings de 2 Conferências simultâneas: "International Conference on Natural Antioxidants and Lipid Peroxidation in Atherosclerosis and Cancer (ALPAC)" e "International Conference on Quality and Safety Aspects and Nutrition in Europe'95 (QSFNE), 22-25 Agosto 1995, Helsínquia, Finlândia.Selenium as a cofactor of glutathione peroxidase, which prevents lipid peroxidation in mammals, takes part in the direct protection of endothelial cells against reactive oxiygen species that have been implicated in atherogenesis; moreover, it is involved in the biosynthesis of arachidonic acid derivatives in platelets and in the regulation of lipoprotein cholesterol metabolism in human beings and in animal models. These aspects are relevant enough to conclude that low selenium status may be related to atherosclerosis and, consequently, to the occurrence of cardiovascular diseases. Clinical studies showed a decrease in plasma selenium of patient’s wilh congestive cardiomyopathy and/or myocardial infarction. A significant inverse correlation between plasma selenium and severity of coronary atherosclerosis was also reported in man. However, prospective epldemiological studies on the relationship between selenium and cardiovascular disease are rather controversial. The aim of this work was to compare the selenium status by determining serum levels of this element in inhabitants of two urban and one rural Portuguese regions.The relationship between serum selenium levels and generally accepted cardiovascular risk factors was also an objetive. In this context, serurn selenium and serum lipid parameters (total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides) were evaluated. Age and sex as well as alcohol and tobacco consumption were also considered

Creation of Risk Score for insurance pricing negotiation of delivery drivers

O objetivo deste estudo consistiu na proposição de uma nova precificação para o seguro de entregadores em uma empresa líder no mercado de food delivery na América Latina, com a finalidade de reduzir os custos elevados relativos ao prêmio pago à seguradora. O objetivo principal foi desenvolver uma metodologia para propor uma nova precificação de seguro, visando a redução dos custos elevados relacionados ao prêmio pago à seguradora. Este estudo realizou uma análise detalhada, estimando a probabilidade de sinistros com base em variáveis como rotas de entrega, modais de transporte, e perfis detalhados dos entregadores. A metodologia adotada envolveu a aplicação de técnicas avançadas de machine learning e análise estatística. Foram empregados modelos como regressão logística e árvores de decisão, os quais foram fundamentais para construir um perfil de risco robusto e realizar uma classificação eficiente de risco. A análise foi sustentada por um conjunto de dados abrangente, incluindo dimensões como frequência de sinistros, características das rotas, e dados demográficos dos entregadores, fornecendo uma base sólida para a modelagem. Os resultados obtidos com a nova metodologia de precificação demonstraram uma redução significativa nos custos de seguro. Isso foi possível pela incorporação de uma avaliação de risco mais precisa e personalizada, que levou em conta o padrão de ocorrência dos sinistros e os comportamentos de risco dos entregadores. Além disso, a precificação proposta ofereceu uma flexibilidade maior na contratação do seguro, tornando-o mais acessível para os entregadores e mais vantajoso para a empresa contratante e a seguradora. A inovação deste estudo reside na utilização de uma abordagem de score de risco baseada na probabilidade de sinistros para a precificação de seguros no segmento de food delivery, evidenciando ser uma alternativa eficiente e viável para a gestão de custos elevados associados ao seguro.The objective of this study was to propose a new pricing model for delivery drivers insurance for a leading food delivery company in Latin America. The aim was to reduce the high costs associated with the premiums paid to the insurance company. To achieve this objective, an analysis was conducted to develop a methodology for proposing a new insurance pricing strategy, targeting the reduction of the high costs associated with the premiums paid to the insurer. This study carried out a detailed analysis, estimating the probability of claims based on variables such as delivery routes, transportation modes, and the detailed profiles of delivery drivers. The adopted methodology involved the application of advanced machine learning and statistical analysis techniques. Models such as logistic regression and decision trees were used, which were fundamental in building a robust risk profile and performing efficient risk classification. The analysis was supported by a comprehensive dataset, including dimensions such as claim frequency, route characteristics, and demographic data of the delivery drivers, providing a solid basis for modeling. The results obtained with the new pricing methodology demonstrated a significant reduction in insurance costs. This was possible due to the incorporation of a more accurate and personalized risk assessment, which took into account the pattern of claims occurrence and the risk behaviors of the delivery drivers. Furthermore, the proposed pricing offered greater flexibility in insurance contracting, making it more accessible for the delivery drivers and more advantageous for both the contracting company and the insurer. The innovation of this study lies in the use of a risk score approach based on the probability of claims for insurance pricing in the food delivery segment, proving to be an efficient and viable alternative for managing the high costs associated with insurance

Epidemiological aspects of the cases of dengue in the south of Mato Grosso, 2002 to 2016

Dengue is an arbovirose that has a great economic impact on society and has a great impact on public health. It is a febrile disease caused by the viral serotypes DEN-1, DEN-2, DEN-3 and DEN-4. This study aimed to describe the epidemiological profile of reported cases of dengue in the period from 2002 to 2016 in a municipality in the interior of the State of Mato Grosso. An epidemiological study of the cross-sectional type of quantitative and descriptive approach was carried out.The data were from the municipality of Rondonópolis (MT), from January 2002 to December 2016, based on sociodemographic and clinical variables, according to the SINAN record. For statistical analysis, absolute and relative frequencies were used, Pearson's chi-square test (p value <0.05) and statistical platform R aid. This study was approved by the Research Ethics Committee of Hospital Júlio Muller (Opinion 1,571,782). In Rondonópolis (MT), from 2002 to 2016, female cases were predominant n = 10471 (52.59%), the age group 31 to 54 years old n = 6996 (35.14%), white race n = 7251 (36.42%) and urban area of residence n = 19114 (96%). The highest number of cases was diagnosed in January n = 4161 (20.89%). A total of 8737 (43.88%) cases were classified as classical dengue, 2520 (12.65%) as autochthonous, 260 corresponded to the critical phase of dengue n = (1.3%) and 17 (0.08%) were of deaths. With the epidemiological profile, the study contributed with necessary information about the characteristics of dengue and can promote improvements in disease control strategies in primary health care