636 research outputs found
Cosmological CMBR dipole in open universes ?
The observed CMBR dipole is generally interpreted as a Doppler effect arising
from the motion of the Earth relative to the CMBR frame. An alternative
interpretation, proposed in the last years, is that the dipole results from
ultra-large scale isocurvature perturbations. We examine this idea in the
context of open cosmologies and show that the isocurvature interpretation is
not valid in an open universe, unless it is extremely close to a flat universe,
.Comment: 26 pages, Latex, 6 figures, to appear in Phys. Rev.
B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure.
Cigarette smoke (CS) is the major cause of chronic lung injuries, such as chronic obstructive pulmonary disease (COPD). In patients with severe COPD, tertiary lymphoid follicles containing B lymphocytes and B cell-activating factor (BAFF) overexpression are associated with disease severity. In addition, BAFF promotes adaptive immunity in smokers and mice chronically exposed to CS. However, the role of BAFF in the early phase of innate immunity has never been investigated. We acutely exposed C57BL/6J mice to CS and show early BAFF expression in the bronchoalveolar space and lung tissue that correlates to airway neutrophil and macrophage influx. Immunostaining analysis revealed that neutrophils are the major source of BAFF. We confirmed in vitro that neutrophils secrete BAFF in response to cigarette smoke extract (CSE) stimulation. Antibody-mediated neutrophil depletion significantly dampens lung inflammation to CS exposure but only partially decreases BAFF expression in lung tissue and bronchoalveolar space suggesting additional sources of BAFF. Importantly, BAFF deficient mice displayed decreased airway neutrophil recruiting chemokines and neutrophil influx while the addition of exogenous BAFF significantly enhanced this CS-induced neutrophilic inflammation. This demonstrates that BAFF is a key proinflammatory cytokine and that innate immune cells in particular neutrophils, are an unconsidered source of BAFF in early stages of CS-induced innate immunity
Generating --cosmologies with perfect fluid in dilaton gravity
We present a method for generating exact diagonal -cosmological
solutions in dilaton gravity coupled to a radiation perfect fluid and with a
cosmological potential of a special type. The method is based on the symmetry
group of the system of -field equations. Several new classes of explicit
exact inhomogeneous perfect fluid scalar-tensor cosmologies are presented.Comment: 10 pages, LaTe
The No-defect Conjecture: Cosmological Implications
When the topology of the universe is non trivial, it has been shown that
there are constraints on the network of domain walls, cosmic strings and
monopoles. I generalize these results to textures and study the cosmological
implications of such constraints. I conclude that a large class of
multi-connected universes with topological defects accounting for structure
formation are ruled out by observation of the cosmic microwave background.Comment: 4 pages, 1 figure, accepted for publication as a brief report in
Phys. Rev.
HST/STIS spectroscopy of the exposed white dwarf in the short-period dwarf nova EK TrA
We present high resolution Hubble Space Telescope ultraviolet spectroscopy of
the dwarf nova EK TrA obtained in deep quiescence. The Space Telescope Imaging
Spectrograph data reveal the broad Ly-alpha absorption profile typical of a
moderately cool white dwarf, overlayed by numerous broad emission lines of He,
C, N, and Si and by a number of narrow absorption lines, mainly of CI and SiII.
Assuming a white dwarf mass in the range 0.3-1.4Msun we derive
Teff=17500-23400K for the primary in EK TrA; Teff=18800K for a canonical mass
of 0.6Msun. From the narrow photospheric absorption lines, we measure the white
dwarf rotational velocity, v*sin i=200+-100kms. Even though the strong
contamination of the photospheric white dwarf absorption spectrum by the
emission lines prevents a detailed quantitative analysis of the chemical
abundances of the atmosphere, the available data suggest slightly sub-solar
abundances. The high time resolution of the STIS data allows us to associate
the observed ultraviolet flickering with the emission lines, possibly
originating in a hot optically thin corona above the cold accretion disk.Comment: 6 pages A&A-Latex, 5 Figures, accepted for publication in A&
DT/T beyond linear theory
The major contribution to the anisotropy of the temperature of the Cosmic
Microwave Background (CMB) radiation is believed to come from the interaction
of linear density perturbations with the radiation previous to the decoupling
time. Assuming a standard thermal history for the gas after recombination, only
the gravitational field produced by the linear density perturbations present on
a universe can generate anisotropies at low z (these
anisotropies would manifest on large angular scales). However, secondary
anisotropies are inevitably produced during the nonlinear evolution of matter
at late times even in a universe with a standard thermal history. Two effects
associated to this nonlinear phase can give rise to new anisotropies: the
time-varying gravitational potential of nonlinear structures (Rees-Sciama RS
effect) and the inverse Compton scattering of the microwave photons with hot
electrons in clusters of galaxies (Sunyaev-Zeldovich SZ effect). These two
effects can produce distinct imprints on the CMB temperature anisotropy. We
discuss the amplitude of the anisotropies expected and the relevant angular
scales in different cosmological scenarios. Future sensitive experiments will
be able to probe the CMB anisotropies beyong the first order primary
contribution.Comment: plain tex, 16 pages, 3 figures. Proceedings of the Laredo Advance
School on Astrophysics "The universe at high-z, large-scale structure and the
cosmic microwave background". To be publised by Springer-Verla
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