994 research outputs found
Quinolines and Related Compounds as Potential Antimalarials
Various 4-and 8-aminoquinoline derivatives having different substituents in the side chain and in the nucleus have been discussed in respect of their antimalarial activity and tolerance dosages. The effect of the incorporation of different moieties e.g. piperazine, piperidine and quinoline itself has also been highlighted. Certain quinoline quinones and benzoquinones as effective antimalarial agents have also been described
Kemijska svojstva i primjena premaznih materijala na bazi vode i organskih otapala na drvu
Wood finishes are used extensively to improve the aesthetic value and protect wood products from moisture. These organic coatings generally contain volatile organic compounds (VOC) as solvents that evaporate when the coatings cure over the surface. Due to strict legislations against these hazardous VOCs, the buyers across the globe are shifting towards products finished with water borne coats. Two of the most commonly used wood coatings in India are polyurethane and nitrocellulose (NC) lacquer. This paper aims at comparing these two wood coatings with their water borne counterparts. The study was conducted on the wood substrate of Melia dubia. Chemical characterization of the cured coats was attempted through FTIR spectroscopy. Physical appearances in terms of gloss and film thickness were also studied. Bands of urethane, urea and nitric groups were identified, which helped in understanding the changes in chemical structure of the finishes after curing. The thickness of the organic coatings was significantly higher than that of their water-borne counterparts. Gloss of water based coatings was observed to be lesser than that of their organic solvent based counterparts in either coating material. In case of lacquer, the reduction was up-to 33 %. whereas in case of PU, gloss dropped down by about 54 %.Premazni se materijali primjenjuju na drvu kako bi se očuvao njegov estetski izgled i drvni proizvodi zaštitili od vlage. Organski premazni materijali u osnovi sadržavaju hlapljive organske spojeve (HOS) kao otapala koja isparavaju dok premazni materijal otvrdnjava na površini drva. Zbog strogih propisa o tim opasnim hlapljivim organskim spojevima kupci diljem svijeta prelaze na vodene premazne materijale. Dva najčešće upotrebljavana premazna materijala za drvo u Indiji jesu poliuretanski i nitrocelulozni (NC) lak. Cilj rada bio je usporediti ta dva
premazna materijala s istim premaznim materijalima na bazi vode. Istraživanje je provedeno na drvu Melia dubia. Kemijska karakterizacija otvrdnutih premaza provedena je primjenom FTIR spektroskopije. Također su proučavani sjaj i debljina filma. Identificirane su skupine uretana, ureje i nitratne skupine koje su pridonijele razumijevanju
promjena u kemijskoj strukturi premaza nakon otvrdnjavanja. Debljina premaza na bazi organskih otapala bila je znatno veća od debljine premaza na bazi vode. Uočeno je da je sjaj premaza na bazi vode manji od sjaja premaza na bazi organskih otapala. Za NC lak to je smanjenje bilo do 33 %, a sjaj PU laka smanjio se za oko 54 %
Physical and optical characteristics of atmospheric aerosols during ICARB at Manora Peak, Nainital: a sparsely inhabited, high-altitude location in the Himalayas
Collocated measurements of the optical and physical properties of columnar and near-surface aerosols were carried out from Manora Peak, Nainital (a sparsely inhabited, high altitude location, ~2 km above mean sea level, in the Himalayas), during the Integrated Campaign for Aerosols, gases and Radiation Budget (ICARB) under the Geosphere Biosphere Programme of the Indian Space Research Organization (ISRO-GBP). Under this, observational data of spectral aerosol optical depths (AOD), mass concentration of aerosol black carbon (MB ), mass concentration (MT ) and number concentration (Nt ) of composite (total) aerosols near the surface and meteorological parameters were collected during the period February 15 to April 30, 2006. Though very low (<0.1 at 500 nm) AODs were observed during clear days, as much as a four-fold increase was seen on hazy days. The Ångström exponent (α), deduced from the spectral AODs, revealed high values during clear days, while on hazy days α was low; with an overall mean value of 0.69 ± 0.06 for the campaign period. BC mass concentration varied between 0.36 and 2.87 μg m-3 and contributed in the range 0.7 to 1.8% to the total aerosol mass. Total aerosol number concentration and BC mass concentration showed diurnal variation with a midnight and early morning minimum and a late afternoon maximum; a pattern quite opposite to that seen in low altitude stations. These are attributed to the dynamics of the atmospheric boundary layer
Photostability of acetylated wood coated with nano zinc oxide
Chemical modification with acetic anhydride is an effective method to stabilise wood against dimensional movement and improve decay resistance of wood. It has also been reported to retard UV light induced color darkening on wood surface. Coatings of wood surfaces with certain nano metal oxides have also shown promise as UV screening agent. In this work, we have evaluated synergistic effect of acetylation of wood and application of nano material on wood surfaces to enhance their UV stability. Photo-stability of acetylated Wrightia tinctoria wood coated with zinc oxide (ZnO) nanodispersion was evaluated by irradiating these wood specimens to UV radiation in an accelerated weathering tester. Acetylation of wood with acetic anhydride exhibited photo-bleaching and inhibited light-induced color darkening observed in unmodified wood. Coating of unmodified and modified wood surfaces with ZnO nanodispersion reduced photo-discolouration and degradation of wood polymers. The photo-bleaching observed in chemically modified wood upon light irradiation was further enhanced by application of nano coating on wood surfaces
Pharmacotherapeutic Options for Visceral Leishmaniasis—Current Scenario
Visceral leishmaniasis (VL) or Kala-azar is a protozoal disease, which was previously regarded as one of the most neglected tropical diseases. Management of this disease is quite difficult, because it is said to affect the poorest of the poor. Previously Sodium Stibogluconate (SSG) was regarded as the gold standard treatment for VL. But due to the increasing unresponsiveness, to this drug various other drugs were tried and are still being tried. Pentamidine is very toxic and has been discarded of late. Amphotericin B and its lipid formulations are very effective but require hospital admission and monitoring. Oral drugs like Miltefosine have already been launched. An amino glycoside Paromomycin and another oral drug Sitamaquine are in the pipe line. Interferon gamma has been used with discouraging results
Multiband optical monitoring of the blazars S5 0716+714 and BL Lacertae
We report results of multiband optical monitoring of two well known blazars,
S5 0716+714 and BL Lacertae, carried out in 1996 and 2000-01 with an aim to
study optical variations on time scales from minutes to hours and longer.The
light curves were derived relative to comparison stars present on the CCD
frames. Night to night flux variations of >0.1 mag were observed in S5 0716+714
during a campaign of ~2 weeks in 1996.A good correlation between the
lightcurves in different optical bands was found for both inter-night and
intra-night observations. Two prominent events of intra-night optical
variability were detected in S5 0716+714.Each of these rapidly varying segments
of the lightcurves trace an exponential flux profile whose rate of variation is
the same in both cases. Our long-term monitoring data of S5 0716+714 showed a
distinct flare around JD 2451875 which can be identified in the BVRI bands.This
flare coincides with the brightest phase recorded during 1994-2001 in the
long-term lightcurves reported by Raiteri et al.(2003). No evidence for the
bluer when brighter trend was noticed on inter-night and intra-night time
scales. On the other hand, our nearly simultaneous multiband observations of BL
Lacertae in October 2001 showed flux variations that were not achromatic. This
blazar was found to become bluer when brighter on intra-night time scales and
there is a hint of the same trend on inter-night time scales. Based on five
nights of observations during a week, BL Lacertae showed a peak night-to-night
variability of ~0.6 mag in B. Thus, we found that the present observations of
the two blazars, reveal a contrasting behaviour in terms of the dependence of
spectral hardening with increasing brightness, at least on intra-night, and
possibly also on inter-night, time scales.Comment: 11 pages with 10 figures,uses mn2e.cls, Accepted for publication in
MNRAS. Tables 4 and 5 in full will be available in the electronic version of
the articl
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