Pregnancy in a diagnosed case of cauda equina syndrome and it’s management: a case report

As with many rare conditions, little is known about cauda equina syndrome (CES) and reproduction. Knowledge pertaining to complications during pregnancy and its management in a patient with diagnosed case of CES is even more scant. The information which we have is from attending on individual cases who presented with CES diagnosed during pregnancy. The following case report demonstrates pregnancy in a known case of CES, diagnosed after sustaining a burst fracture of lumbar vertebrae followed by surgical decompression at puberty. Patient conceived spontaneously with residual disease as symptoms of perineal numbness, sensory deficit in both lower limbs and persistent saddle hypoesthesia along with foot drop and gait abnormalities and presented at 30 weeks of gestation. CES is an unusual entity that appears in between 2-6% of all cases of disc herniation in the lumbar segment. Related post-traumatic presentations are extremely rare. Pregnancy exacerbates most problems associated with spinal cord injury. Autonomic dysreflexia may present as a complication in a case of pregnancy with CES which may be life threatening and requires immediate treatment. Antenatal management and complications of pregnancy in a diagnosed case of CES has not been documented till date

Pharmaceutical Marketing: A Literature Review

Marketing is the essence businesses and the business fraternity globally have accepted this norm of marketing the products effectively in order to achieve desired results. One of the premier and global Industry is Pharmaceutical Industry. It has a wide range of scope right from over the counter (OTC) products to life savings drugs to medical equipments. So much so that Medical Education at large includes a separate section as Pharmaceutical Education and this premium education experiences builds the base for Pharma Product manufacturing. Getting across these products to the Market requires essential skills and hence it signifies the efforts of Pharmaceutical Marketing. As against the Marketing of general product, Pharma Marketing involves further more essentialities as it belongs to the category of useful & needy products but not desired products as one never plans in general to buy a medicine or medical equipment unless prescribed or advised under medical care. This factor poses the massive challenge in the field of Pharmaceutical marketing. The Review paper attempts to understand the essence & concept of Pharmaceutical Marketing. It further aims to massively review the existing literature on Pharmaceutical Marketing and present the inferences. This conceptual study is completed with the help of Secondary data. It encompasses the thoughts of authors & researchers who have contributed to the Pharmaceutical Marketing domain. The Review has been categorised into studies of Marketing Mix, Consumer Behaviour towards Pharma Products, Green Marketing approach and execution of Pharma Marketing. The Papers & literature reviewed have been selected on Author’s convenience & judgement, which may result in the limitation for study and the inferences presented may be indicative rather exhaustive

Silent primary ovarian ectopic pregnancy following ovulation induction: diagnostic dilemma

Early diagnosis of an ovarian pregnancy, of all the diagnoses relating to extrauterine gestations, is perhaps a diagnostic challenge faced by an obstetrician and a radiologist. About 0.5% of extrauterine implantations occur in the ovary. Recent studies have demonstrated infertility and Assisted reproductive techniques (ARTs), multiparity, use of intrauterine devices as risk factors for ovarian ectopic. Knowledge pertaining to ovulation induction and risk of ovarian ectopic is even more scant. In this article, we report a case report of ovarian pregnancy following ovulation induction with letrozole. Patient visited with history of missed menstrual period, mild abdominal pain and a weakly positive urine pregnancy test. Provisional diagnosis of right tubal ectopic was made. Diagnosis of ruptured ovarian ectopic was made on explorative laparoscopy which was later confirmed histopathologically. Patient had normal intra and post-operative course. An ovarian ectopic can present as a life-threatening condition and a high index of suspicion can prevent morbidity as well as mortality. Ovarian pregnancy in a primigravida with ovulation induction without an alarming sign, as in this case, is the rarest entity came across till date

Implementation of threats detection modeling with Deep learning in IoT botnet attack environment

IoT forensics where security and privacy are the key concern as the data the majorly hold personal information. So how to work on the vulnerabilities available from the IoT environment and classify them to get the best results to perform the forensics is covered in the paper. In IoT forensics botnet dataset analysed using deep learning classification to get the understanding that how deep learning can be used effectively for forensic analysis. So, research work provides advanced digital forensics methods i.e., collection of evidence and analysis of dataset for IoT forensics implementation. Since a decade ago, we are seeing a reality where hacking into a client's PC utilizing small bots or blocking a gathering of interconnected gadgets is not any more unthinkable. These little bots are called botnets (e.g., Mirai, Torii and so on.), which are a gathering of deadly codes that can obstruct the whole security. As Internet of Things (IoT) is developing quickly, the interconnected gadgets are helpless to penetrate as one influenced gadget can crumple the entire system. As Internet of Things (IoT) is developing quickly, the interconnected gadgets are defenseless to break as one influenced gadget can hamper the entire system. The security danger stays as botnet assaults increment their essence to the interconnected gadgets. In this work, we are proposing a novel correlation between AI (SVM and KNN) and profound learning draws near (Neural system) to discover which approach creates better outcome while learning the assault designs. Research explores the IoT forensics analysis. In IoT forensics models were applied on a composite information storehouse which was made by consolidating the outcomes found from the examination we did on Torii botnet test, with the CTU-13 dataset of botnet assaults on IoT environment

Cataract and its risk factor among adults residing in South Bihar, India

Background: Cataract is considered as one of the most common causes of visual impairment and the leading cause of blindness in the world. Age related cataract occurs in people above 50 years of age and the its pathogenesis is multifactorial. Therefore, the present study was aimed to assess the prevalence and risk factors for cataract.Methods: Community based cross sectional study was conducted among adults residing at urban areas of South Bihar. The data was collected by interview method, using pre-tested semi-structured questionnaire which contains socio-demographic data, dietary habits, history of diabetes or hypertension, family history of cataract and long-term sun exposure.Results: Among 240 participants, 94 (39.2%) were male and 146 (60.8%) were female. Maximum participants were aged more than 70 years. The prevalence of cataract was 52.1%.Conclusions: The prevalence of cataract was quite high and was significantly associated with age, long term sun exposure and family history of cataract

The Effects of Organizational Culture on Employee Performance: A Study of the Edge Newspaper

This research aims to examine the effect of organizational culture on employee performance. The research was conducted by interviewing the Edge Newspaper Sdn Bhd Company’s top management and their employees. Apart from that, data collection will be based on observations from surveys and journals. These collected data were used to test our hypothesis that is ‘A good employee behaviour will increase business productivity, lower absenteeism, and achieve turnover”. It is proven that a positive relationship exists between organizational culture and employee behaviour. These findings provide new insights for the management of the effects of organizational culture on its employee performances. In addition, this research enhances the understanding of employee behaviour, possibly utilized by top management to encourage and manage their employees

Decolorization and partial mineralization of a polyazo dye by Bacillus firmus immobilized within tubular polymeric gel

The degradation of C.I. Direct red 80, a polyazo dye, was investigated using Bacillus firmus immobilized by entrapment in tubular polymeric gel. This bacterial strain was able to completely decolorize 50 mg/L of C.I. Direct red 80 under anoxic conditions within 12 h and also degrade the reaction intermediates (aromatic amines) during the subsequent 12 h under aerobic conditions. The tubular gel harboring the immobilized cells consisted of anoxic and aerobic regions integrated in a single unit which was ideal for azo dye degradation studies. Results obtained show that effective dye decolorization (97.8%), chemical oxygen demand (COD) reduction (91.7%) and total aromatic amines removal were obtained in 15 h with the immobilized bacterial cell system whereas for the free cells, a hydraulic residence time of 24 h was required for an equivalent performance in a sequential anoxic and aerobic process. Repeated-batch experiments indicate the immobilized cells could decolorize C.I. Direct red 80 and reduce medium COD in five successive batch runs with enhanced activity obtained after each consecutive run, thus suggesting its stability and potential for repeated use in wastewater treatment. UV–visible spectrophotometry and HPLC analysis were used to confirm the partial mineralization of the dye. Data from this study could be used as a reference for the development of effective industrial scale biotechnological process for the removal of dyes and their metabolites in textile wastewater

Removal of arsenic by Acidothiobacillus ferrooxidans bacteria in bench scale fixed-bed bioreactor system

In the present study arsenic contaminated simulated water and groundwater was treated by the combination of biological oxidation of tri-valent arsenite [As (III)] to penta-valent arsenate [As (V)] in presence of Acidothiobacillus ferrooxidans bacteria and its removal by adsorptive filtration in a bioreactor system. This method includes the immobilisation of A.ferrooxidans on Granulated Activated Carbon (GAC) capable of oxidising ferrous [Fe (II)] to ferric [Fe (III)]. The Fe (III) significantly converts the As (III) to As (V) and ultimately removed greater than 95% by the bed of GAC, limestone, and sand. The significant influence of Fe (II) concentration (0.1–1.5 gL−1), flowrate (0.06–0.18 Lh−1), and initial As (III) concentration (100–1000 μgL−1) on the arsenic removal efficiency was investigated. The simulated water sample containing the different concentration of As (III) and other ions was used in the study. The removal of other co-existing ions present in contaminated water was also investigated in column study. The concentration of arsenic was found to be <10 μgL−1 which is below Maximum Contaminant Level (MCL) as per WHO in treated water. The results confirmed that the present system including adsorptive-filtration was successfully used for the treatment of contaminated water containing As (III) ions