114 research outputs found

    How HRM control affects boundary-spanning employees’ behavioural strategies and satisfaction : The moderating impact of cultural performance orientation

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    This study examines how cultural performance orientation moderates the influence of human resource management (HRM) controls on boundary-spanning employees’ behavioural strategies and satisfaction.HRM control; national culture; performance orientation; boundary-spanning employees; salespeople

    Πειραματική μελέτη της συμπεριφοράς σε κόπωση ρωγματωμένων πλακών αλουμινίου ενισχυμένων με σύθετα υλικά

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    Εθνικό Μετσόβιο Πολυτεχνείο--Μεταπτυχιακή Εργασία. Διεπιστημονικό-Διατμηματικό Πρόγραμμα Μεταπτυχιακών Σπουδών (Δ.Π.Μ.Σ.) “Ναυτική και Θαλάσσια Τεχνολογία και Επιστήμη

    Εισαγωγή στην Κ-θεωρία των C*-αλγεβρών και το θεώρημα ταξινόμησης του Elliott

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    Στην παρούσα διπλωματική εργασία αρχικά δίνεται μια σύντομη εισαγωγή στην Κ-θεωρία των C*-αλγεβρών. Η θεωρία αυτή έχει τις ρίζες της στην τοπολογική Κ-θεωρία, η οποία αναπτύχθηκε από τους Atiyah και Hirzebruch κατά τη διάρκεια της δεκαετίας του 1960, βασιζόμενη στην δουλειά του Grothendieck στην αλγεβρική γεωμετρία. Εισήχθη ως εργαλείο στην θεωρία των C*-αλγεβρών στις αρχές του 1970, όταν ο George Elliott απέδειξε πως οι AF-άλγεβρες ταξινομούνται μέσω των Κ_0-ομάδων τους όταν αυτές εφοδιαστούν με μια κατάλληλη σχέση διάταξης. Η συγκεκριμένη απόδειξη παρουσιάζεται στο δεύτερο μέρος αυτής της εργασίας.In this thesis we first give a brief introduction to K-theory for C*-algebras, which has its roots in (topological) K-theory. K-theory was developed by Atiyah and Hirzebruch in the 1960s based on work of Grothendieck in algebraic geometry. It was introduced as a tool in C*-algebra theory in the early 1970s when George Elliott proved that AF-algebras (the so-called "approximately finite dimensional " C*-algebras) are classified by their ordered K_0-groups. This proof takes place in the second part of this thesis

    Learning Graph Representations for Influence Maximization

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    As the field of machine learning for combinatorial optimization advances, traditional problems are resurfaced and readdressed through this new perspective. The overwhelming majority of the literature focuses on small graph problems, while several real-world problems are devoted to large graphs. Here, we focus on two such problems: influence estimation, a #P-hard counting problem, and influence maximization, an NP-hard problem. We develop GLIE, a Graph Neural Network (GNN) that inherently parameterizes an upper bound of influence estimation and train it on small simulated graphs. Experiments show that GLIE provides accurate influence estimation for real graphs up to 10 times larger than the train set. More importantly, it can be used for influence maximization on considerably larger graphs, as the predictions ranking is not affected by the drop of accuracy. We develop a version of CELF optimization with GLIE instead of simulated influence estimation, surpassing the benchmark for influence maximization, although with a computational overhead. To balance the time complexity and quality of influence, we propose two different approaches. The first is a Q-network that learns to choose seeds sequentially using GLIE's predictions. The second defines a provably submodular function based on GLIE's representations to rank nodes fast while building the seed set. The latter provides the best combination of time efficiency and influence spread, outperforming SOTA benchmarks.Comment: 2

    Prognostic factors of atrial fibrillation following elective coronary artery bypass grafting: the impact of quantified intraoperative myocardial ischemia

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    <p>Abstract</p> <p>Background</p> <p>Atrial fibrillation (AF) occurs in 28-33% of the patients undergoing coronary artery revascularization (CABG). This study focuses on both pre- and peri-operative factors that may affect the occurrence of AF. The aim is to identify those patients at higher risk to develop AF after CABG.</p> <p>Patients and methods</p> <p>Two patient cohorts undergoing CABG were retrospectively studied. The first group (group A) consisted of 157 patients presenting AF after elective CABG. The second group (group B) consisted of 191 patients without AF postoperatively.</p> <p>Results</p> <p>Preoperative factors presenting significant correlation with the incidence of post-operative AF included: 1) age > 65 years (p = 0.029), 2) history of AF (p = 0.022), 3) chronic obstructive pulmonary disease (p = 0.008), 4) left ventricular dysfunction with ejection fraction < 40% (p = 0.015) and 5) proximal lesion of the right coronary artery (p = 0.023). The intraoperative factors that appeared to have significant correlation with the occurrence of postoperative AF were: 1) CPB-time > 120 minutes (p = 0.011), 2) myocardial ischemia index < 0.27 ml.m<sup>2</sup>/Kg.min (p = 0.011), 3) total positive fluid-balance during ICU-stay (p < 0.001), 4) FiO<sub>2</sub>/PO<sub>2 </sub>> 0, 4 after extubation and during the ICU-stay (p = 0.021), 5) inotropic support with doses 15-30 μg/Kg/min (p = 0.016), 6) long ICU-stay recovery for any reason (p < 0.001) and perioperative myocardial infarction (p < 0.001).</p> <p>Conclusions</p> <p>Our results suggest that the incidence of post-CABG atrial fibrillation can be predicted by specific preoperative and intraoperative measures. The intraoperative myocardial ischemia can be sufficiently quantified by the myocardial ischemia index. For those patients at risk we would suggest an early postoperative precautionary anti-arrhythmic treatment.</p

    Management of venous thromboembolism in pregnancy

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    Venous thromboembolism (VTE) in pregnancy, consisting of deep venous thrombosis (DVT) and pulmonary embolism (PE), is a major factor of maternal mortality. Several patient-specific risk factors along with the physiologic changes of pregnancy promote a state of hypercoagulability in pregnant women. Detailed assessment of all pregnant women can establish a risk profile that would guide clinical decisions, and balance potential therapeutic benefits with side effects. Differentiating between physiologic changes of pregnancy and symptoms of VTE can be challenging and warrants meticulous clinical evaluation. Timely and accurate diagnosis of VTE with proper imaging is essential for its management, and systemic anticoagulation remains the cornerstone of VTE prevention and therapy. Furthermore, advanced invasive treatment options such as inferior vena cava filters and thrombectomy can be considered for complex cases. Importantly, the risk of systemic anticoagulation should be balanced against the risk of VTE-associated morbidity and mortality for mother and fetus, and an informed decision should be made. In this review, we present an up-to-date overview of VTE management in pregnancy and the postpartum period. Keywords: Anticoagulants; Deep venous thrombosis; Pregnancy; Pulmonary embolism; Venous thromboembolism

    Large asymptomatic Left Atrial Myxoma with ossification: case report

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    <p>Abstract</p> <p>Background</p> <p>Atrial myxomas are the most common primary cardiac tumors. They are usually small or moderate in size by the time of the diagnosis, exhibiting non specific cardiac or systemic symptoms, and are most frequently soft and friable without microscopic signs of ossification. We describe herein an extremely rare case of an asymptomatic giant left atrial myxoma with angiographic neovascularization and ossification.</p> <p>Case presentation</p> <p>An asymptomatic 58-year-old male with a giant left atrial tumor, was transferred to our Unit for surgical treatment. The tumor was an incidental finding during a work-up for hemoptysis due to bronchectasis. The coronary angiogram showed tumor vessels originating from the RCA. The tumor macroscopically did not resemble a myxoma, considering its dimensions (12 × 10 cm) and its solid substance. The mass was excised together with the interatrial septum and the right lateral LA wall close to the right pulmonary veins orifices. The defect was closed with Dacron patches in order to prevent malformation of both atria. The pathology study revealed a benign myxoma with excessive osteoid (mature bone) content.</p> <p>Conclusion</p> <p>We consider our case as extremely rare because of the asymptomatic course despite the large size of the tumor, the blood supply from the right coronary artery and the bone formation.</p

    Ground‐to‐GEO optical feeder links for very high throughput satellite networks: Accent on diversity techniques

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    This paper studies the use of optical feeder links in very high throughput satellites (VHTS) networks with emphasis on gateway diversity techniques to mitigate the inherent propagation losses in optical frequencies. Focusing on a GEO scenario, the paper considers a system‐wide approach investigating various challenges of optical feeder links. These include transmission schemes amenable for transparent on‐board processing, optical channel models taking into account blockage by clouds and fading caused by atmospheric turbulence in addition to complexity of on‐board and on‐ground processing. The channel models are then used to dimension the ground segment towards ensuring a given availability percentage (e.g., 99.9%). The channel model and payload complexity further influence the choice of link layer techniques used for counteracting fading due to atmospheric turbulence in the absence of blockage. An elaborate end‐to‐end simulator incorporating the proposed channel models capturing the nuances of various processing blocks like optical‐electrical conversion is developed. The system performance results provide interesting insights and a framework for assessing the feasibility and advantages of optical feeder links in VHTS systems

    Effect of the Novel Influenza A (H1N1) Virus in the Human Immune System

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    BACKGROUND: The pandemic by the novel H1N1 virus has created the need to study any probable effects of that infection in the immune system of the host. METHODOLOGY/PRINCIPAL FINDINGS: Blood was sampled within the first two days of the presentation of signs of infection from 10 healthy volunteers; from 18 cases of flu-like syndrome; and from 31 cases of infection by H1N1 confirmed by reverse RT-PCR. Absolute counts of subtypes of monocytes and of lymphocytes were determined after staining with monoclonal antibodies and analysis by flow cytometry. Peripheral blood mononuclear cells (PBMCs) were isolated from patients and stimulated with various bacterial stimuli. Concentrations of tumour necrosis factor-alpha, interleukin (IL)-1beta, IL-6, IL-18, interferon (FN)-alpha and of IFN-gamma were estimated in supernatants by an enzyme immunoassay. Infection by H1N1 was accompanied by an increase of monocytes. PBMCs of patients evoked strong cytokine production after stimulation with most of bacterial stimuli. Defective cytokine responses were shown in response to stimulation with phytohemagglutin and with heat-killed Streptococcus pneumoniae. Adaptive immune responses of H1N1-infected patients were characterized by decreases of CD4-lymphocytes and of B-lymphocytes and by increase of T-regulatory lymphocytes (Tregs). CONCLUSIONS/SIGNIFICANCE: Infection by the H1N1 virus is accompanied by a characteristic impairment of the innate immune responses characterized by defective cytokine responses to S.pneumoniae. Alterations of the adaptive immune responses are predominated by increase of Tregs. These findings signify a predisposition for pneumococcal infections after infection by H1N1 influenza
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