Surviving and Thriving in the New World of Web Aggregators

This paper examines the development of aggregators, entities that collect information from a wide range of sources, with or without prior arrangements, and add value through post-aggregation services. New Web-page extraction tools, context sensitive mediators, and agent technologies have greatly reduced the barriers to constructing aggregators. We predict that aggregators will soon emerge in industries where they were not formerly present. Through studying over a hundred existing and emerging aggregators, we present a model for understanding the aggregator's strategic interaction with the incumbent. We also suggest different business models as possible aggregator entry points into an industry and describe their impact

Glass-Embedded Fan-Out Antenna-in-Packaging for 5G Millimeter Wave Applications

The paper proposes a novel Antenna-in-Packaging (AiP) structure design for 60 GHz, millimeter wave WiFi applications. In the AiP design, single- or double-sided glass redistribution layers were embedded in a typical fan-out (FO) packaging structure to introduce design flexibility and to improve the radiation properties of the antenna. ANSYS-HFSS software was employed for electromagnetic (EM) characteristic simulations on the fan-out AiP (FO_AiP) design. To improve antenna radiation performance, single factor analyses were first performed to study the impact of each of the design parameters. A consecutive procedure followed to find more suitable combinations of the design parameters. As a result, two typical glass-embedded FO_AiP structures - one with 7.6 GHz bandwidth plus 4.7 dB gain and upward radiation, and another with 5.3 GHz bandwidth plus 5.2 dB gain and downward radiation, are proposed for the 60 GHz applications

Modulation of Synaptic Plasticity by Stress Hormone Associates with Plastic Alteration of Synaptic NMDA Receptor in the Adult Hippocampus

Stress exerts a profound impact on learning and memory, in part, through the actions of adrenal corticosterone (CORT) on synaptic plasticity, a cellular model of learning and memory. Increasing findings suggest that CORT exerts its impact on synaptic plasticity by altering the functional properties of glutamate receptors, which include changes in the motility and function of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype of glutamate receptor (AMPAR) that are responsible for the expression of synaptic plasticity. Here we provide evidence that CORT could also regulate synaptic plasticity by modulating the function of synaptic N-methyl-D-aspartate receptors (NMDARs), which mediate the induction of synaptic plasticity. We found that stress level CORT applied to adult rat hippocampal slices potentiated evoked NMDAR-mediated synaptic responses within 30 min. Surprisingly, following this fast-onset change, we observed a slow-onset (>1 hour after termination of CORT exposure) increase in synaptic expression of GluN2A-containing NMDARs. To investigate the consequences of the distinct fast- and slow-onset modulation of NMDARs for synaptic plasticity, we examined the formation of long-term potentiation (LTP) and long-term depression (LTD) within relevant time windows. Paralleling the increased NMDAR function, both LTP and LTD were facilitated during CORT treatment. However, 1–2 hours after CORT treatment when synaptic expression of GluN2A-containing NMDARs is increased, bidirectional plasticity was no longer facilitated. Our findings reveal the remarkable plasticity of NMDARs in the adult hippocampus in response to CORT. CORT-mediated slow-onset increase in GluN2A in hippocampal synapses could be a homeostatic mechanism to normalize synaptic plasticity following fast-onset stress-induced facilitation

Glass-Embedded Fan-Out Antenna-in-Packaging for 5G Millimeter Wave Applications

The paper proposes a novel Antenna-in-Packaging (AiP) structure design for 60 GHz, millimeter wave WiFi applications. In the AiP design, single- or double-sided glass redistribution layers were embedded in a typical fan-out (FO) packaging structure to introduce design flexibility and to improve the radiation properties of the antenna. ANSYS-HFSS software was employed for electromagnetic (EM) characteristic simulations on the fan-out AiP (FO_AiP) design. To improve antenna radiation performance, single factor analyses were first performed to study the impact of each of the design parameters. A consecutive procedure followed to find more suitable combinations of the design parameters. As a result, two typical glass-embedded FO_AiP structures - one with 7.6 GHz bandwidth plus 4.7 dB gain and upward radiation, and another with 5.3 GHz bandwidth plus 5.2 dB gain and downward radiation, are proposed for the 60 GHz applications

The impact of university STEM assets:A systematic review of the empirical evidence

Background Innovation ecosystems are an important driver of regional economic growth and development. STEM assets connected to universities may play an important role in such ecosystems. Objective To systematically review the literature relating to the effect of university STEM assets on regional economies and innovation ecosystems, providing a better understanding of how the impact is generated and constrained, as well as identifying any gaps in knowledge. Methods Keyword and text word searches using the Web of Science Core Collection (Clarivate), Econlit (EBSCO) and ERIC (EBSCO) were performed in July 2021 and February 2023. Papers were double screened on abstract and title, and were included if there was consensus that they fulfilled the inclusion criteria of: (i) relating to an OECD country; (ii) having been published between 1 January 2010 and 28 February 2023; and (iii) concerning the impact of STEM assets. Data extraction was undertaken for each article by a single reviewer and checked by a second reviewer. Due to the heterogeneity of the study designs and outcome measures used, it was not possible to perform a quantitative synthesis of results. A narrative synthesis was subsequently undertaken. Results Of the 162 articles identified for detailed review, 34 were accepted as being sufficiently relevant to the study to be included for final analysis. Three important features identified were that the literature: i) is predominately concerned with supporting new businesses; ii) describes a high level of involvement with a university in providing that support; and iii studies economic impacts at local, regional and national levels. Discussion The evidence points to a gap in the literature relating to looking at the broader impact of STEM assets and any corresponding transformational, system-level effects that go beyond narrowly defined, short to medium-term outcomes. The main limitation of this review is that information on STEM assets in the non-academic literature is not captured