Dynamics of Q-Balls in an expanding universe

We analyse the evolution of light Q-balls in a cosmological background, and find a number of interesting features. For Q-balls formed with a size comparable to the Hubble radius, we demonstrate that there is no charge radiation, and that the Q-ball maintains a constant physical radius. Large expansion rates cause charge migration to the surface of the Q-ball, corresponding to a non-homogeneous internal rotation frequency. We argue that this is an important phenomenon as it leads to a large surface charge and possible fragmentation of the Q-ball. We also explore the deviation of the Q-ball profile function from the static case. By introducing a parameter $\epsilon$, which is the ratio of the Hubble parameter to the frequency of oscillation of the Q-ball field, and using solutions to an analytically approximated equation for the profile function, we determine the dependence of the new features on the expansion rate. This allows us to gain an understanding of when they should be considered and when they can be neglected, thereby placing restrictions on the existence of homogeneous Q-balls in expanding backgrounds.Comment: 5 pages, 4 figure

Genomic structure and expression of uncoupling protein 2 genes in rainbow trout (Oncorhynchus mykiss)

Background Uncoupling protein 2 (UCP2) belongs to the superfamily of mitochondrial anion carriers that dissociate the respiratory chain from ATP synthesis. It has been determined that UCP2 plays a role in several physiological processes such as energy expenditure, body weight control and fatty acid metabolism in several vertebrate species. We report the first characterization of UCP2 s in rainbow trout (Oncorhynchus mykiss). Results Two UCP2 genes were identified in the rainbow trout genome, UCP2A and UCP2B. These genes are 93% similar in their predicted amino acid sequences and display the same genomic structure as other vertebrates (8 exons and 7 introns) spanning 4.2 kb and 3.2 kb, respectively. UCP2A and UCP2B were widely expressed in all tissues of the study with a predominant level in macrophage-rich tissues and reproductive organs. In fry muscle we observed an increase in UCP2B expression in response to fasting and a decrease after refeeding in agreement with previous studies in human, mouse, rat, and marsupials. The converse expression pattern was observed for UCP2A mRNA which decreased during fasting, suggesting different metabolic roles for UCP2A and UCP2B in rainbow trout muscle. Phylogenetic analysis including other genes from the UCP core family located rainbow trout UCP2A and UCP2B with their orthologs and suggested an early divergence of vertebrate UCPs from a common ancestor gene. Conclusion We characterized two UCP2 genes in rainbow trout with similar genomic structures, amino acid sequences and distribution profiles. These genes appeared to be differentially regulated in response to fasting and refeeding in fry muscle. The genomic organization and phylogeny analysis support the hypothesis of a common ancestry between the vertebrate UCPs

Gauge Threshold Corrections for Local Orientifolds

We study gauge threshold corrections for systems of fractional branes at local orientifold singularities and compare with the general Kaplunovsky-Louis expression for locally supersymmetric N=1 gauge theories. We focus on branes at orientifolds of the C^3/Z_4, C^3/Z_6 and C^3/Z_6' singularities. We provide a CFT construction of these theories and compute the threshold corrections. Gauge coupling running undergoes two phases: one phase running from the bulk winding scale to the string scale, and a second phase running from the string scale to the infrared. The first phase is associated to the contribution of N=2 sectors to the IR beta functions and the second phase to the contribution of both N=1 and N=2 sectors. In contrast, naive application of the Kaplunovsky-Louis formula gives single running from the bulk winding mode scale. The discrepancy is resolved through 1-loop non-universality of the holomorphic gauge couplings at the singularity, induced by a 1-loop redefinition of the twisted blow-up moduli which couple differently to different gauge nodes. We also study the physics of anomalous and non-anomalous U(1)s and give a CFT description of how masses for non-anomalous U(1)s depend on the global properties of cycles.Comment: 44 page

A toy model of fractal glioma development under RF electric field treatment

A toy model for glioma treatment by a radio frequency electric field is suggested. This low-intensity, intermediate-frequency alternating electric field is known as the tumor-treating-field (TTF). In the framework of this model the efficiency of this TTF is estimated, and the interplay between the TTF and the migration-proliferation dichotomy of cancer cells is considered. The model is based on a modification of a comb model for cancer cells, where the migration-proliferation dichotomy becomes naturally apparent. Considering glioma cancer as a fractal dielectric composite of cancer cells and normal tissue cells, a new effective mechanism of glioma treatment is suggested in the form of a giant enhancement of the TTF. This leads to the irreversible electroporation that may be an effective non-invasive method of treating brain cancer.Comment: Submitted for publication in European Physical Journal

Model building with intersecting D6-branes on smooth Calabi-Yau manifolds

We study intersecting D6-branes in Calabi-Yau manifolds that are smooth hypersurfaces in weighted projective spaces. We develop the techniques for calculating intersection numbers between special Lagrangian sub-manifolds defined as fixed loci of anti-holomorphic involutions. We present global Pati-Salam and MSSM-like models that are supersymmetric up to a decoupled hidden sector.Comment: 29p

D-Terms from Generalized NS-NS Fluxes in Type II

Orientifolds of type II string theory admit a certain set of generalized NS-NS fluxes, including not only the three-form field strength H, but also metric and non-geometric fluxes, which are related to H by T-duality. We describe in general how these fluxes appear as parameters of an effective N=1 supergravity theory in four dimensions, and in particular how certain generalized NS-NS fluxes can act as charges for R-R axions, leading to D-term contributions to the effective scalar potential. We illustrate these phenomena in type IIB with the example of a certain orientifold of T^6/Z_4.Comment: 31+1 pages, uses utarticle.cls; v2: references adde

Non-geometric flux vacua, S-duality and algebraic geometry

The four dimensional gauged supergravities descending from non-geometric string compactifications involve a wide class of flux objects which are needed to make the theory invariant under duality transformations at the effective level. Additionally, complex algebraic conditions involving these fluxes arise from Bianchi identities and tadpole cancellations in the effective theory. In this work we study a simple T and S-duality invariant gauged supergravity, that of a type IIB string compactified on a $T^6/(Z_2 x Z_2)$ orientifold with O3/O7-planes. We build upon the results of recent works and develop a systematic method for solving all the flux constraints based on the algebra structure underlying the fluxes. Starting with the T-duality invariant supergravity, we find that the fluxes needed to restore S-duality can be simply implemented as linear deformations of the gauge subalgebra by an element of its second cohomology class. Algebraic geometry techniques are extensively used to solve these constraints and supersymmetric vacua, centering our attention on Minkowski solutions, become systematically computable and are also provided to clarify the methods.Comment: 47 pages, 10 tables, typos corrected, Accepted for Publication in Journal of High Energy Physic

AdS Vacua, Attractor Mechanism and Generalized Geometries

We consider flux vacua attractor equations in type IIA string theory compactified on generalized geometries with orientifold projections. The four-dimensional N=1 superpotential in this compactification can be written as the sum of the Ramond-Ramond superpotential and a term described by (non)geometric flux charges. We exhibit a simple model in which supersymmetric AdS and Minkowski solutions are classified by means of discriminants of the two superpotentials. We further study various configurations without Ramond-Ramond flux charges. In this case we find supersymmetric AdS vacua both in the case of compactifications on generalized geometries with SU(3) x SU(3) structures and on manifolds with an SU(3)-structure without nongeometric flux charges. In the latter case, we have to introduce correction terms into the prepotential in order to realize consistent vacua.Comment: 35 pages, accepted version in JHE

Moduli Redefinitions and Moduli Stabilisation

Field redefinitions occur in string compactifications at the one loop level. We review arguments for why such redefinitions occur and study their effect on moduli stabilisation and supersymmetry breaking in the LARGE volume scenario. For small moduli, although the effect of such redefinitions can be larger than that of the $\alpha'$ corrections in both the K\"ahler and scalar potentials, they do not alter the structure of the scalar potential. For the less well motivated case of large moduli, the redefinitions can dominate all other terms in the scalar potential. We also study the effect of redefinitions on the structure of supersymmetry breaking and soft terms.Comment: 21 pages, 3 figures; v2. references adde