1,118 research outputs found
Defining and Exploring Animal Sentience
One of the commentaries on the target article notes that animal sentience is difficult to define operationally. This response to the commentaries develops a working, usable definition of animal sentience and examines the relationships between animal emotions and sentience
Two-dimensional projections of an hypercube
We present a method to project a hypercube of arbitrary dimension on the
plane, in such a way as to preserve, as well as possible, the distribution of
distances between vertices. The method relies on a Montecarlo optimization
procedure that minimizes the squared difference between distances in the plane
and in the hypercube, appropriately weighted. The plane projections provide a
convenient way of visualization for dynamical processes taking place on the
hypercube.Comment: 4 pages, 3 figures, Revtex
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Smart packaging for photonics
Unlike silicon microelectronics, photonics packaging has proven to be low yield and expensive. One approach to make photonics packaging practical for low cost applications is the use of {open_quotes}smart{close_quotes} packages. {open_quotes}Smart{close_quotes} in this context means the ability of the package to actuate a mechanical change based on either a measurement taken by the package itself or by an input signal based on an external measurement. One avenue of smart photonics packaging, the use of polysilicon micromechanical devices integrated with photonic waveguides, was investigated in this research (LDRD 3505.340). The integration of optical components with polysilicon surface micromechanical actuation mechanisms shows significant promise for signal switching, fiber alignment, and optical sensing applications. The optical and stress properties of the oxides and nitrides considered for optical waveguides and how they are integrated with micromechanical devices were investigated
The TatC component of the twin-arginine protein translocase functions as an obligate oligomer
The Tat protein export system translocates folded proteins across the bacterial cytoplasmic membrane and the plant thylakoid membrane. The Tat system in Escherichia coli is composed of TatA, TatB and TatC proteins. TatB and TatC form an oligomeric, multivalent receptor complex that binds Tat substrates, while multiple protomers of TatA assemble at substrate-bound TatBC receptors to facilitate substrate transport. We have addressed whether oligomerisation of TatC is an absolute requirement for operation of the Tat pathway by screening for dominant negative alleles of tatC that inactivate Tat function in the presence of wild-type tatC. Single substitutions that confer dominant negative TatC activity were localised to the periplasmic cap region. The variant TatC proteins retained the ability to interact with TatB and with a Tat substrate but were unable to support the in vivo assembly of TatA complexes. Blue-native PAGE analysis showed that the variant TatC proteins produced smaller TatBC complexes than the wild-type TatC protein. The substitutions did not alter disulphide crosslinking to neighbouring TatC molecules from positions in the periplasmic cap but abolished a substrate-induced disulphide crosslink in transmembrane helix 5 of TatC. Our findings show that TatC functions as an obligate oligomer.</p
Concurrent Bounded Model Checking
The Definitive Version can be found in the ACM Digital Library here: http://dx.doi.org/10.1145/2693208.2693240issue_date: January 2015 numpages: 5 acmid: 2693240 keywords: Bounded Model Checking, Concurrency, Symbolic Executionissue_date: January 2015 numpages: 5 acmid: 2693240 keywords: Bounded Model Checking, Concurrency, Symbolic Executionissue_date: January 2015 numpages: 5 acmid: 2693240 keywords: Bounded Model Checking, Concurrency, Symbolic Executio
Optical application and measurement of torque on microparticles of isotropic nonabsorbing material
We show how it is possible to controllably rotate or align microscopic
particles of isotropic nonabsorbing material in a TEM00 Gaussian beam trap,
with simultaneous measurement of the applied torque using purely optical means.
This is a simple and general method of rotation, requiring only that the
particle is elongated along one direction. Thus, this method can be used to
rotate or align a wide range of naturally occurring particles. The ability to
measure the applied torque enables the use of this method as a quantitative
tool--the rotational equivalent of optical tweezers based force measurement. As
well as being of particular value for the rotation of biological specimens,
this method is also suitable for the development of optically-driven
micromachines.Comment: 8 pages, 6 figure
Glassiness and constrained dynamics of a short-range non-disordered spin model
We study the low temperature dynamics of a two dimensional short-range spin
system with uniform ferromagnetic interactions, which displays glassiness at
low temperatures despite the absence of disorder or frustration. The model has
a dual description in terms of free defects subject to dynamical constraints,
and is an explicit realization of the ``hierarchically constrained dynamics''
scenario for glassy systems. We give a number of exact results for the statics
of the model, and study in detail the dynamical behaviour of one-time and
two-time quantities. We also consider the role played by the configurational
entropy, which can be computed exactly, in the relation between fluctuations
and response.Comment: 10 pages, 9 figures; minor changes, references adde
Exploring morphological correlations among H2CO, 12CO, MSX and continuum mappings
There are relatively few H2CO mappings of large-area giant molecular cloud
(GMCs). H2CO absorption lines are good tracers for low-temperature molecular
clouds towards star formation regions. Thus, the aim of the study was to
identify H2CO distributions in ambient molecular clouds. We investigated
morphologic relations among 6-cm continuum brightness temperature (CBT) data
and H2CO (111-110; Nanshan 25-m radio telescope), 12CO (1--0; 1.2-m CfA
telescope) and midcourse space experiment (MSX) data, and considered the impact
of background components on foreground clouds. We report simultaneous 6-cm H2CO
absorption lines and H110\alpha radio recombination line observations and give
several large-area mappings at 4.8 GHz toward W49 (50'\times50'), W3
(70'\times90'), DR21/W75 (60'\times90') and NGC2024/NGC2023 (50'\times100')
GMCs. By superimposing H2CO and 12CO contours onto the MSX color map, we can
compare correlations. The resolution for H2CO, 12CO and MSX data was about 10',
8' and 18.3", respectively. Comparison of H2CO and 12CO contours, 8.28-\mu m
MSX colorscale and CBT data revealed great morphological correlation in the
large area, although there are some discrepancies between 12CO and H2CO peaks
in small areas. The NGC2024/NGC2023 GMC is a large area of HII regions with a
high CBT, but a H2CO cloud to the north is possible against the cosmic
microwave background. A statistical diagram shows that 85.21% of H2CO
absorption lines are distributed in the intensity range from -1.0 to 0 Jy and
the \Delta V range from 1.206 to 5 km/s.Comment: 18 pages, 22 figures, 5 tables. Accepted to be published in
Astrophysics and Space Scienc
Tomato: a crop species amenable to improvement by cellular and molecular methods
Tomato is a crop plant with a relatively small DNA content per haploid genome and a well developed genetics. Plant regeneration from explants and protoplasts is feasable which led to the development of efficient transformation procedures.
In view of the current data, the isolation of useful mutants at the cellular level probably will be of limited value in the genetic improvement of tomato. Protoplast fusion may lead to novel combinations of organelle and nuclear DNA (cybrids), whereas this technique also provides a means of introducing genetic information from alien species into tomato. Important developments have come from molecular approaches. Following the construction of an RFLP map, these RFLP markers can be used in tomato to tag quantitative traits bred in from related species. Both RFLP's and transposons are in the process of being used to clone desired genes for which no gene products are known. Cloned genes can be introduced and potentially improve specific properties of tomato especially those controlled by single genes. Recent results suggest that, in principle, phenotypic mutants can be created for cloned and characterized genes and will prove their value in further improving the cultivated tomato.
Finding a moral homeground: appropriately critical religious education and transmission of spiritual values
Values-inspired issues remain an important part of the British school curriculum. Avoiding moral relativism while fostering enthusiasm for spiritual values and applying them to non-curricular learning such as school ethos or children's home lives are challenges where spiritual, moral, social and cultural (SMSC) development might benefit from leadership by critical religious education (RE). Whether the school's model of spirituality is that of an individual spiritual tradition (schools of a particular religious character) or universal pluralistic religiosity (schools of plural religious character), the pedagogy of RE thought capable of leading SMSC development would be the dialogical approach with examples of successful implementation described by Gates, Ipgrave and Skeie. Marton's phenomenography, is thought to provide a valuable framework to allow the teacher to be appropriately critical in the transmission of spiritual values in schools of a particular religious character as evidenced by Hella's work in Lutheran schools
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