Shared Print Initiatives

This paper provides an overview of the history, issues, challenges, opportunities, and obligations associated with shared print programs. Many of the library operational activities associated with participating in a shared print program have precedents or shared concerns with other operational work around collection development, preservation, and staffing in general. Activities at Emory University serve as examples for participating in shared print programs

Collections Data, Tools, and Strategy: Applying R, Tableau, and Excel to Print Assessment

As is the case at most academic libraries, collection assessment has become an essential component of collection management and development work. Although much of the assessment focus has disproportionately fallen on e-resources, print collections remain fruitful areas for evaluation and review. At Emory, print collections, including a complex approval plan, continue to be a significant component of our overarching collection strategy (in volume and expenditure). However, shifting priorities for library space and the growth of interdisciplinary programs and centers within the University are placing a higher demand on subject librarians for communication and coordinated decision-making regarding print acquisitions. As a result, we are currently preparing for a comprehensive print collection review, of which the approval plan is an integral component. This assessment will inform a more coherent print strategy, which effectively and efficiently meets research and teaching requirements as well as administrative needs. Using data cleaning and visualization tools, such as R, Excel, and Tableau, we have enriched our local usage data with detailed Gobi approval data (e.g., series, publisher, subject, etc.) and profile parameters. Merging these data types and enriching local use data will allow us to analyze the print collection in a more nuanced fashion and ask questions that do not require the LC classification framework. This analysis considers the development of additional tools and approaches that facilitate subject specialist communication with collection management and overall collaborative decision-making, especially in cross disciplinary areas

2016 top trends in academic libraries A review of the trends and issues affecting academic libraries in higher education

Every other year, the ACRL Research Planning and Review Committee produces a document on top trends in higher education as they relate to academic librarianship. The 2016 Top Trends report discusses research data services, digital scholarship, collection assessment trends, content provider mergers, evidence of learning, new directions with the ACRL Framework for Information Literacy, altmetrics, emerging staff positions, and open educational resources

2018 Top Trends in Academic Libraries

Every other year, the ACRL Research Planning and Review Committee produces a document on top trends in higher education as they relate to academic librarianship. Topics in this edition of ACRL Top Trends will be familiar to some readers who will hopefully learn of new materials to expand their knowledge. Other readers will be made aware of trends that are outside of their experience. This is the nature of trends in our current technological and educational environments: change is continual, but it affects different libraries at different rates. The 2018 top trends share several overarching themes, including the impact of market forces, technology, and the political environment on libraries

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Reports of conferences, institutes and seminars

This quarter’s column offers several reports from the Electronic Resources & Libraries Conference held in Austin, Texas, on March 4–7, as well as coverage of sessions from the American Library Association Annual Conference, which took place in New Orleans, Louisiana, June 21–26. A handful of reports were also collected from the Library Publishing Forum in Minneapolis, Minnesota, on May 21–23; Ex Libris Users in North America (ELUNA) in Spokane, Washington, on May 1–4; Acquisitions Institute at Timberline Lodge in Oregon on May 19–21, and finally the NASIG conference in Atlanta, Georgia, on June 8–11. Topics covered include electronic resource tracking, trials, and troubleshooting; equity and diversity in acquisitions; technical services workflows; systems migrations; and library publishing pedagogy and open access

Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma

We report here the molecular cloning of an approximately 1-Mb region of recurrent amplification at 20q13.2 in breast cancer and other tumors and the delineation of a 260-kb common region of amplification. Analysis of the 1-Mb region produced evidence for five genes, ZNF217, ZNF218, and NABC1, PIC1L (PIC1-like), CYP24, and a pseudogene CRP (Cyclophillin Related Pseudogene). ZNF217 and NABC1 emerged as strong candidate oncogenes and were characterized in detail. NABC1 is predicted to encode a 585-aa protein of unknown function and is overexpressed in most but not all breast cancer cell lines in which it was amplified. ZNF217 is centrally located in the 260-kb common region of amplification, transcribed in multiple normal tissues, and overexpressed in all cell lines and tumors in which it is amplified and in two in which it is not. ZNF217 is predicted to encode alternately spliced, Kruppel-like transcription factors of 1,062 and 1,108 aa, each having a DNA-binding domain (eight C2H2 zinc fingers) and a proline-rich transcription activation domain

Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma

We report here the molecular cloning of an ≈1-Mb region of recurrent amplification at 20q13.2 in breast cancer and other tumors and the delineation of a 260-kb common region of amplification. Analysis of the 1-Mb region produced evidence for five genes, ZNF217, ZNF218, and NABC1, PIC1L (PIC1-like), CYP24, and a pseudogene CRP (Cyclophillin Related Pseudogene). ZNF217 and NABC1 emerged as strong candidate oncogenes and were characterized in detail. NABC1 is predicted to encode a 585-aa protein of unknown function and is overexpressed in most but not all breast cancer cell lines in which it was amplified. ZNF217 is centrally located in the 260-kb common region of amplification, transcribed in multiple normal tissues, and overexpressed in all cell lines and tumors in which it is amplified and in two in which it is not. ZNF217 is predicted to encode alternately spliced, Kruppel-like transcription factors of 1,062 and 1,108 aa, each having a DNA-binding domain (eight C2H2 zinc fingers) and a proline-rich transcription activation domain