Swarm-intelligent search for gravitational waves from eccentric binary mergers

We implement an eccentric search for compact binary mergers based on particle swarm optimization. The orbital eccentricity is an invaluable input for understanding the formation scenarios of the binary mergers and can play a pivotal role in finding their electromagnetic counterparts. Current modelled searches rely on pre-computed template banks that are computationally expensive and resistant towards expanding the search parameter space dimensionality. On the other hand, particle swarm optimization offers a straightforward algorithm that dynamically selects template points while exploring an arbitrary dimensional parameter space. Through extensive evaluation using simulated signals from spin-aligned eccentric binary mergers, we discovered that the search exhibits a remarkable autonomy in capturing the effects of both eccentricity and spin. We describe our search pipeline and revisit some of the merger candidates from the gravitational wave transient catalogs

Mpemba effect in a system of an overdamped particle in a double well potential: exact results and other properties

The Mpemba effect refers to the anomalous relaxation phenomenon wherein an initially hotter system equilibrates faster than an initially colder system when both are quenched to the same low temperature. Experiments on a single colloidal particle trapped in a carefully shaped double well potential have demonstrated the effect. In this paper, we present an exact analysis, based on the eigenspectrum analysis of the corresponding Fokker-Planck equation, of the Mpemba effect in such systems by considering a piece-wise linear double well potential. The role of metastable states in the energy landscape as well as the initial distribution of the population of the particle in its confined domain is discussed. We also show that a metastable state is not a necessary condition for the Mpemba effect.Comment: 13 pages, 9 figure

Anti-termite activity of essential oil and its components from Myristica fragrans against Microcerotermes beesoni

The essential oil obtained by hydrodistillation of the fruits of Myristica fragrans was analyzed by GC and GC-MS. Twenty eight compounds were identified representing 95.9% of the oil. The major constituents of the oil were α-pinene (6.4%), Sabinene (37.7%), β-pinene (7.3%), myrcene (3.5%),Limonene (4.7%),Terpine-4-ol (5.8%), safrole (3.4%) and myristicin (6.8%).The essential oil and its major constituents were evaluated at different dilution against Microcerotermes beesoni, test termite. The LC50 value of fruit essential oil is 28.6 mg/g. Furthermore, exposure to myristicin caused 100% mortality at a dosage of 5 mg/g after 14d. @JASEMJ. Appl. Sci. Environ. Manage. Sept, 2011, Vol. 15 (3) 559 - 56

Assessment of Ground Water Quality of Ghazipur District, Eastern Uttar Pradesh, India, Special Reference to Arsenic Contamination

Now a days water quality has solicited a major global concern due to ever increasing human developmental activities that over exploit and pollute the water resources on surface and underground. Situation is very worst in developing as well as developed nations. In this context the status of water quality of Gazhipur district of Eastern Uttar Pradesh of India was carried out for the present study to identify the arsenic contamination of ground water. Arsenic contamination in ground water in India was first identified in lower Ganga plain of West Bengal later on Bihar, Jharkhand and also apprehended in Uttar Pradesh. Keeping the view to arsenic contamination in adjacent district Ballia, the present investigation therefore has been undertaken the possible arsenic contamination in and around Ghazipur district of eastern Uttar Pradesh

Cold Injury Prevention and Management in High Altitude Extreme Environments Pharmacological and Therapeutical Interventions

Cold injury refers to local or systemic body response that occurs due to massive loss of body heat when the body is exposed to extremely cold temperatures. The current modalities for the prevention and management of cold injury(ies) are very limited due to the paucity of availability of targeted therapeutics. Pathophysiological cascades in cold injury include: (a) desensitization of sensory neurons can be manifest as a result of altered pathophysiological functions viz., Ca2+ imaging, calcitonin gene-related peptide release, expressions of inflammatory mediators (PGE2: prostaglandin E2, NGF: nerve growth factors), (b) inflammatory markers viz.; interleukins (IL-1β, IL-6, and IL-10), tumor necrosis factor-alpha (TNF-α), and CD62E/endothelial-leukocyte adhesion molecule 1 (E-selectin); (c) oxidative stress markers associated with cold injury measured through serum level of protein carbonyl, 4-hydroxy-2-nonenal (4-HNE), superoxide dismutase (SODs), advanced oxidative protein products (AOPP) and nitrotyrosine; (d) endothelial damage: nitric oxide (NO), prostacyclin (PGI2), reactive oxygen species (ROS), Von-Willebrand factor (VWF), CD31/PECAM-1 (platelet/endothelial cell adhesion molecule 1), CD36/SR-B3 (scavenger receptor class B member 3) and tissue-type plasminogen activator (TTPA). In this review paper, we elaborate on the current state-of-the-art pharmacological interventions for cold injury that may be beneficial in developing novel and targeted therapeutics for the prevention, management, and treatment of cold injury

Presentation of an ingested foreign body as a vesical calculus: a common condition, but uncommon presentation

Vesical calculus is a common entity in children of developing countries. Foreign body ingestion is a common occurrence in the pediatric population. An ingested foreign body eroding into the urinary bladder and leading to the formation of a vesical calculus is an extremely rare condition. We encountered a 14-year-old girl who presented with a vesical calculus and a history of ingestion of a nut bolt 7 years earlier. After cystolithotomy and retrieval of the calculus, we noticed that the nut bolt formed its core. As it is an extremely uncommon presentation, it is being reported here, with a brief review of the literature.Keywords: foreign body calculus, foreign body ingestion, vesical calculus, vesicointestinal fistul

Diverse MicroRNAs-mRNA networks regulate the priming phase of mouse liver regeneration and of direct hyperplasia

OBJECTIVES: Adult hepatocytes are quiescent cells that can be induced to proliferate in response to a reduction in liver mass (liver regeneration) or by agents endowed with mitogenic potency (primary hyperplasia). The latter condition is characterized by a more rapid entry of hepatocytes into the cell cycle, but the mechanisms responsible for the accelerated entry into the S phase are unknown. MATERIALS AND METHODS: Next generation sequencing and Illumina microarray were used to profile microRNA and mRNA expression in CD‐1 mice livers 1, 3 and 6 h after 2/3 partial hepatectomy (PH) or a single dose of TCPOBOP, a ligand of the constitutive androstane receptor (CAR). Ingenuity pathway and DAVID analyses were performed to identify deregulated pathways. MultiMiR analysis was used to construct microRNA‐mRNA networks. RESULTS: Following PH or TCPOBOP we identified 810 and 527 genes, and 102 and 10 miRNAs, respectively, differentially expressed. Only 20 genes and 8 microRNAs were shared by the two conditions. Many miRNAs targeting negative regulators of cell cycle were downregulated early after PH, concomitantly with increased expression of their target genes. On the contrary, negative regulators were not modified after TCPOBOP, but Ccnd1 targeting miRNAs, such as miR‐106b‐5p, were downregulated. CONCLUSIONS: While miRNAs targeting negative regulators of the cell cycle are downregulated after PH, TCPOBOP caused downregulation of miRNAs targeting genes required for cell cycle entry. The enhanced Ccnd1 expression may explain the more rapid entry into the S phase of mouse hepatocytes following TCPOBOP

Anti-termite activity of essential oil and its components from Myristica fragrans against Microcerotermes beesoni

The essential oil obtained by hydrodistillation of the fruits of Myristica fragrans was analyzed by GC and GC-MS. Twenty eight compounds were identified representing 95.9% of the oil. The major constituents of the oil were \u3b1-pinene (6.4%), Sabinene (37.7%), \u3b1-pinene (7.3%), myrcene (3.5%),Limonene (4.7%),Terpine-4-ol (5.8%), safrole (3.4%) and myristicin (6.8%).The essential oil and its major constituents were evaluated at different dilution against Microcerotermes beesoni , test termite. The LC50 value of fruit essential oil is 28.6 mg/g. Furthermore, exposure to myristicin caused 100% mortality at a dosage of 5 mg/g after 14d