Escore funcional e de dor após cirurgia de hérnia de disco lombar e fisioterapia precoce = Funcional and pain score after lumbar disc surgery and early physiotherapy

Objetivos: Avaliar o efeito da intervenção fisioterapêutica no escore funcional e de dor dos pacientes submetidos à cirurgia de hérnia de disco lombar (HDL). Métodos: Estudo randomizado, controlado e cego, avaliando pacientes que internaram no Hospital São Lucas da PUCRS, no período de outubro de 2003 a maio de 2004, para realizar cirurgia de HDL. Amostra: 20 pacientes, 10 do grupo controle (cirurgia e repouso no pós-operatório) e 10 do grupo de intervenção (cirurgia e fisioterapia no pós-operatório). Intervenção fisioterapêutica: alongamento neural do ciático, alongamentos de Williams e uso da estimulação elétrica transcutânea três vezes ao dia, do primeiro dia pós-operatório até a alta hospitalar. Instrumentos para avaliar o escore de dor e de função, respectivamente: escala análogo-visual de dor e Roland Morris Questionnaire. Escores avaliados antes da cirurgia, no pós-operatório imediato e dois meses após os procedimentos. Resultados: Houve significância estatística na diferença do escore funcional (P = 0,009) e na redução da intensidade da dor (P = 0,028) dos pacientes no segundo mês pós-operatório, favorecendo o grupo com intervenção fisioterapêutica. Conclusões: A intervenção precoce de fisioterapia contribuiu para melhorar o estado funcional e reduzir a dor dos pacientes nos dois primeiros meses após o procedimento cirúrgico de HD

O diagnóstico dos tumóres do encéfalo pela ventriculografia

Continuação de: v. 18, n. 3, p. 85-102, mar. 193

No Túmulo do Professor Eduardo Sarmento Leite da Fonseca Discurso Proferido pelo Prof. Eliseu Paglioli

No Túmulo do Professor Eduardo Sarmento Leite da Fonseca Discurso Proferido pelo Prof. Eliseu Pagliol

Spontaneous subdural hematoma associated to Duret hemorrhage

AbstractSubdural hematoma (SH) is a neurosurgical emergency, usually caused by head trauma. Non-traumatic causes include aneurysm or arterial–venous malformation rupture, coagulopathy and others. We report the case of a 66year-old man who developed apparently unprovoked signs of increased intracranial pressure. Brain computed tomography scan showed an acute spontaneous SH, surgically treated. Throughout surgery, a ruptured cortical artery with intensive bleeding appeared and was cauterized. After surgery, patient remained comatose and a new CT demonstrated Duret hemorrhage at the brainstem. Acute spontaneous SH of arterial origin is rare and highly lethal, in which a good prognosis relies on early diagnosis and treatment

Micoses do Sistema Nervoso. Estudo de dois casos.

Micoses do Sistema Nervoso. Estudo de dois casos

The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission

Ongoing challenges in diagnosing focal cortical dysplasia (FCD) mandate continuous research and consensus agreement to improve disease definition and classification. An International League Against Epilepsy (ILAE) Task Force (TF) reviewed the FCD classification of 2011 to identify existing gaps and provide a timely update. The following methodology was applied to achieve this goal: a survey of published literature indexed with ((Focal Cortical Dysplasia) AND (epilepsy)) between 01/01/2012 and 06/30/2021 (n = 1349) in PubMed identified the knowledge gained since 2012 and new developments in the field. An online survey consulted the ILAE community about the current use of the FCD classification scheme with 367 people answering. The TF performed an iterative clinico-pathological and genetic agreement study to objectively measure the diagnostic gap in blood/brain samples from 22 patients suspicious for FCD and submitted to epilepsy surgery. The literature confirmed new molecular-genetic characterizations involving the mechanistic Target Of Rapamycin (mTOR) pathway in FCD type II (FCDII), and SLC35A2 in mild malformations of cortical development (mMCDs) with oligodendroglial hyperplasia (MOGHE). The electro-clinical-imaging phenotypes and surgical outcomes were better defined and validated for FCDII. Little new information was acquired on clinical, histopathological, or genetic characteristics of FCD type I (FCDI) and FCD type III (FCDIII). The survey identified mMCDs, FCDI, and genetic characterization as fields for improvement in an updated classification. Our iterative clinico-pathological and genetic agreement study confirmed the importance of immunohistochemical staining, neuroimaging, and genetic tests to improve the diagnostic yield. The TF proposes to include mMCDs, MOGHE, and “no definite FCD on histopathology” as new categories in the updated FCD classification. The histopathological classification can be further augmented by advanced neuroimaging and genetic studies to comprehensively diagnose FCD subtypes; these different levels should then be integrated into a multi-layered diagnostic scheme. This update may help to foster multidisciplinary efforts toward a better understanding of FCD and the development of novel targeted treatment options

Avaliação das propriedades eletrofisiológica de neurônios hipocampais humanos no modelo de 0-Mg2+

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O diagnóstico dos tumores do encéfalo pela ventriculografia

Extrato da obra "Ventriculografia cerebral" do mesmo autor. Edição da Livraria do Globo, 1938, Porto AlegreContinua em: v. 18, n. 4, p. 121-162, abr. 193

O diagnóstico dos tumores do encéfalo pela ventriculografia

Extrato da obra "Ventriculografia cerebral" do mesmo autor. Edição da Livraria do Globo, 1938, Porto AlegreContinua em: v. 18, n. 4, p. 121-162, abr. 193