Prospectus, September 26, 1979

SMALL CHANGE BY FOOD SERVICE; Goba\u27s prayer for all; Letter to editor: Apathy justified?; U. of I. wants YOU!; Submit originals NOW!; Visual Art grad returns; To be at U. of I. tonight: Otrabanda appears; Long livers learn disco, activities fill program; Weight Program starts; BEOG increases; Student government discusses issues; Mental retardation causes and helps; Krannert features the Young Illini; Parkland Board okays budget; College Community Board promotes togetherness; Local student FFA president; Sistercelebration; Birth Defects Any Cures?; Everybody lights up for Styx concert; U. of I. finds Twain treasures; Trilingual comedy this weekend; N.O.W. fights back in rally Fri.; Leaf burning can begin October 1; W.I.R.E. forms Oct. 1-7 p.m.; Classifieds; Karate meets; Illini ranked 13th: Penthouse lists bottom 20; New players, field, for baseball; V-ball wrap-up; Illini starting time changed; Fast Freddy Contest; Freddy goes 8-5https://spark.parkland.edu/prospectus_1979/1011/thumbnail.jp

Prospectus, January 23, 1980

CHANGES TO START THE 80S; College hosts Telethon; Board of Trustees meeting listed; Bad weather stations to tune to; Week in Review: World, Nation, State; Records were made to be broken: Alpine skiing in Illinois can be dangerous; SIU-C to have Guest Day; Five weeks of travel and study in Spain available in the summer; U. of I. visitation set for Feb. 8; Campus Question: Do you think the Americans should boycott the Moscow Olympics?; Play in the band; Medicare 7, 8 or 9 to perform; Batik exhibit on display; Three courses on gardening, pests, and diseases offered; Birthday celebration in Feb. for Susan B. Anthony features dramatic readings, and play; Slew of music courses available; Religion course and Creative Workshop offered; Prospectus makes format changes; Letters to the Editor: Handicapped are human, Thanks from PATH, Article comments, Likes SUPRHOLDR; Fall semester Honors List totals 510; Opening available in teacher aide program; Job hopping causes paycheck losses; Best films of the 70s rated; Coins may value more than the silver it has; U. of I. physicist predicts weather: Keep smiling -- next year will be worse; Krannert events are listed; Volunteers wanted to help U. of I. visually impaired students to study; Burnham accepted as pre-admission site; Statewide campaign recruits applicants for law enforcement positions; Mariott\u27s seeks talent; Classifieds; Setbacks don\u27t hamper Cobra play, yet; Women B-ballers keep on winning, snare PC Invitational crown; Women\u27s Schedule -- 1980; Boys\u27 Schedule; Parkland College Track Schedule 1980 Indoor; Women pull out close one to win over Lincoln Land; Bench Warmer: Olympic dream becoming a continuous nightmare; Three Cobras place first; Bowl games ruin Freddy\u27s average; B-ball even after win; Women\u27s softball to have meetinghttps://spark.parkland.edu/prospectus_1980/1041/thumbnail.jp

Prospectus, October 10, 1979

WORLD PREMIERE AT PC; WPCD Top 20; Foreigners plan celebration; Stugo surveys spring break; S.T.O. to give keg in raffle; Leslie views Parkland as an advantage; Survey will help design new food facilities; Nursing gets rolling with record enrollment; Child rearing at PC; Parkland Food Survey; Three part life at PC; Calif. group at PC Tues.; Avionics meeting; Feature: Numbers unimportant, just good music for Irish; Rally for no taxes Monday; Concerts: Kansas stages show; WPCD to add new program; Classifieds; EMT workshop conducted at PC; Prospectus to publish Images; Reviews: \u27Runner\u27 doesn\u27t stumble, Python religion, Buffest sings about islands, and islands, Talking Heads unafraid of the fear of music; V-ball sees the light, look for good week; Women Cobras prepare for season; Freddy continues loss skein; Fast Freddy Contest; Intramural Standingshttps://spark.parkland.edu/prospectus_1979/1009/thumbnail.jp

Prospectus, December 5, 1979

MAC EXCITES CU; Canteen tries deli; Disposable lighters are like dynamite; Bad weather procedures; MTD raises prices; Across the globe; In the nation; Around the state; Letters to the editor: Response to Scott, Article clarified, Iran: no blackmail; Campus Question: Will MTD increase affect you; Ski Club celebrates; Promotion committee hopes to rejuvenate downtown Urbana; Tooth Buzz; \u27A Christmas Carol\u27 off key; Reviews: \u27Mac\u27 outclassed itself; Classifieds; Faculty Focus: Sex at high noon; Comebacks become cardiac Cobras trademark; Orange Fever catching CU; Women hit highs and lowshttps://spark.parkland.edu/prospectus_1979/1001/thumbnail.jp

Prospectus, October 24, 1979

SURVEY MAKES WAVES; The Week in Review: Across the globe, In the nation, Throughout the state, Around the town, Etc….; Briefs: College to host math contest, Parkland Players present \u27Dracula\u27, Summary of board listed, Champaign council approves bonds, Women\u27s program seeks young blood, Monticello council to discuss tax rate, Program on strokes to be presented, Arthritis program to be presented, Future educators program tomorrow, Nutritionm health, disease are topics, Store celebrates 1st; Letter to editor: Dean congratulates foreigners; Weekly Calendar; Area high schools to visit campus; S.T.O. raffle winners are announced; Give a little blood, then see blood; Women at Home on Tuesday; Editorial: Censorship at WPCD?; PATH raises grievances; Pumpkins and costumes in contest next week; Lincoln Square has art show; Oktoberfest today: a taste of German; Reviews: Ending to the beat has better taste, B-52s: a glimpse of future and past; Classifieds; Music club has enthusiasm; Athletic and rec fields near completion; V-ball gains momentum; Golf team advances to state; Elam blows off competition: harriers 3rd; PC hosts golf, gets 2nd; Fast Freddy loses again; Fast Freddy Contesthttps://spark.parkland.edu/prospectus_1979/1007/thumbnail.jp

Prospectus, May 7, 1980

STAERKEL ANNOUNCES ADDITIONS, CHANGES TO TAKE PLACE BEFORE FALL; Inflation plan announced; Interest-gathering accounts: big financial changes for U.S.; Walsh, Wienke to be 1980-81 co-editors; Resolution is just a suggestion; Youngersters voicing opinions on candidates; Trikes: the new mode of transportation; Special Olympics teaches student; Spring fever in college; Krannert events are listed; Letters to the Editor; REO still favorite in the Midwest; Dates to live by; Movie tells of anti-war movement in \u2760s; Rec students provide overnight camp-out; The sky\u27s the limit; Classifieds; C-U \u27turned upside down\u27 by punch of Journey and Ramones; Training for women; Trackmen win Region, smash state records; Parkland bows out of Section, prepares for conference tourney; Cobras lose at State; Complete Parkland Statisticshttps://spark.parkland.edu/prospectus_1980/1027/thumbnail.jp

Prospectus, October 17, 1979

CANTEEN STILL IN TROUBLE; Language: Big adjustment; Across the globe; In the nation; Throughout the state; Around the town; Fire guts Athenaeum; Briefs: \u27Living Newspaper\u27 performs Oct. 23, German foods, Seniors to visit, Costumes display, Apply no more, Ciricle K events, Krannert events; Letter to editor: Ohio inmate wants pen-pal; Field trips to view artwork; French cooking offered Weds.; I.O.E. to evaluate Parkland College Oct. 30; Everyone would like a Vette; Feature: Fast Freddie wows women; Reviews: \u27Long Run\u27 ran, Science fiction and yesteryear unite in \u27time after time\u27, STYX book-album; Jumping out of a plane -- FOR FUN; Classifieds; Concerts: Frampton -- yea, Simms -- nay, Kenny Loggins storms C-U; Cross Country running well; Outlaws are a crowd pleaser; Sports: Cobras win 4 more; Superman Fast Freddy did it again? 4-9; Freddy\u27s picks; Fast Freddy Contest; Intramural Standingshttps://spark.parkland.edu/prospectus_1979/1008/thumbnail.jp

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570