Malle's conjecture for fair counting functions

We show that the naive adaptation of Malle's conjecture to fair counting functions is not true in general.Comment: 21 page

Prediction of forces and moments for hypersonic flight vehicle control effectors

This research project includes three distinct phases. For completeness, all three phases of the work are briefly described in this report. The goal was to develop methods of predicting flight control forces and moments for hypersonic vehicles which could be used in a preliminary design environment. The first phase included a preliminary assessment of subsonic/supersonic panel methods and hypersonic local flow inclination methods for such predictions. While these findings clearly indicated the usefulness of such methods for conceptual design activities, deficiencies exist in some areas. Thus, a second phase of research was conducted in which a better understanding was sought for the reasons behind the successes and failures of the methods considered, particularly for the cases at hypersonic Mach numbers. This second phase involved using computational fluid dynamics methods to examine the flow fields in detail. Through these detailed predictions, the deficiencies in the simple surface inclination methods were determined. In the third phase of this work, an improvement to the surface inclination methods was developed. This used a novel method for including viscous effects by modifying the geometry to include the viscous/shock layer

Factor Mapping and Metamodelling

In this work we present some techniques, within the realm of Global Sensitivity Analysis, which permit to address fundamental questions in term of model's understanding. In particular we are interested in developing tools which allow to determine which factor (or group of factors) are most responsible for producing model outputs Y within or outside specified bounds ranking the importance of the various input factors in terms of their influence on the variation of Y. On the other hand, we look for representing in a direct way (graphically, analytically, etc.) the relationship between input factors X_1,..., X_k and output Y in order to get a better understanding of the model itself.JRC.G.9-Econometrics and statistical support to antifrau

Wagging the Dogma Tissue-Specific Cell Cycle Control in the Mouse Embryo

AbstractThe family of cyclin-dependent kinases (Cdks) lies at the core of the machinery that drives the cell division cycle. Studies in cultured mammalian cells have provided insight into the cellular functions of many Cdks. Recent Cdk and cyclin knockouts in the mouse show that the functions of G1 cell cycle regulatory genes are often essential only in specific cell types, pointing to our limited understanding of tissue-specific expression, redundancy, and compensating mechanisms in the Cdk network

The contribution of the major planet search surveys to EChO target selection

The EChO core science will be based on a three tier survey, each with increasing sensitivity, in order to study the population of exo-planets from super-Earths to Jupiter-like planets, in the very hot to temperate zones (temperatures of 300 K - 3000 K) of F to M-type host stars. To achieve a meaningful outcome an accurate selection of the target sample is needed. In this paper we analyse the targets, suitable for EChO observations, expected to result from a sample of present and forthcoming detection surveys. Exoplanets currently known are already sufficient to provide a large and diverse sample. However we expect the results from these surveys to increase the sample of smaller planets that will allow us to optimize the EChO sample selection.Comment: Submitted to Experimental Astronom