4,224 research outputs found
Some Methods for Assessing the Need for Non-linear Models in Business Cycle Analysis and Forecasting
There is a long tradition in business cycle analysis of arguing that non-linear models are needed to explain the business cycle. In recent years many non-linear models have been fitted to data on GDP for many countries, but particularly for the U.S. In this paper we set our criteria to evaluate the success of non-linear models in explaining the cycle and then evaluate three recent models in the light of these criteria. We find that the models are capable of explaining the "shape" of expansions, something linear models cannot do, but do so at the cost of making expansions longer than they should be and in producing transition probabilities to recessions that are too low.business cyles, non-linear models
A Finite-Size Scaling Study of a Model of Globular Proteins
Grand canonical Monte Carlo simulations are used to explore the metastable
fluid-fluid coexistence curve of the modified Lennard-Jones model of globular
proteins of ten Wolde and Frenkel (Science, v277, 1975 (1997)). Using both
mixed-field finite-size scaling and histogram reweighting methods, the joint
distribution of density and energy fluctuations is analyzed at coexistence to
accurately determine the critical-point parameters. The subcritical coexistence
region is explored using the recently developed hyper-parallel tempering Monte
Carlo simulation method along with histogram reweighting to obtain the density
distributions. The phase diagram for the metastable fluid-fluid coexistence
curve is calculated in close proximity to the critical point, a region
previously unattained by simulation.Comment: 17 pages, 10 figures, 2 Table
Phase Behavior of Short Range Square Well Model
Various Monte Carlo techniques are used to determine the complete phase
diagrams of the square well model for the attractive ranges
and . The results for the latter case are in agreement with
earlier Monte Carlo simulations for the fluid-fluid coexistence curve and yield
new results for the liquidus-solidus lines. Our results for
are new. We find that the fluid-fluid critical point is metastable for both
cases, with the case being just below the threshold value for
metastability. We compare our results with prior studies and with experimental
results for the gamma-II crystallin.Comment: 8 figures, 1 tabl
Genetic Variants and Phenotypic Characteristics ofSalmonellaTyphimurium-Resistant Mutants after Exposure to Carvacrol
The emergence of antimicrobial resistance has raised questions about the safety of essential oils and their individual constituents as food preservatives and as disinfection agents. Further research is required to understand how and under what conditions stable genotypic resistance might occur in food pathogens. Evolution experiments onSalmonellaTyphimurium cyclically exposed to sublethal and lethal doses of carvacrol permitted the isolation of SeSCar and SeLCar strains, respectively. Both evolved strains showed a significant increase in carvacrol resistance, assessed by minimum inhibitory and bactericidal concentrations, the study of growth kinetics in the presence of carvacrol, and the evaluation of survival under lethal conditions. Moreover, antibiotic susceptibility tests revealed a development of SeLCar resistance to a wide range of antibiotics. Whole genome sequencing allowed the identification of single nucleotide variations in transcriptional regulators of oxidative stress-response:yfhPin SeSCar andsoxRin SeLCar, which could be responsible for the increased resistance by improving the response to carvacrol and preventing its accumulation inside the cell. This study demonstrates the emergence of S. Typhimurium-resistant mutants against carvacrol, which might pose a risk to food safety and should therefore be considered in the design of food preservation strategies, or of cleaning and disinfection treatments
Role of solvent for globular proteins in solution
The properties of the solvent affect the behavior of the solution. We propose
a model that accounts for the contribution of the solvent free energy to the
free energy of globular proteins in solution. For the case of an attractive
square well potential, we obtain an exact mapping of the phase diagram of this
model without solvent to the model that includes the solute-solvent
contribution. In particular we find for appropriate choices of parameters upper
critical points, lower critical points and even closed loops with both upper
and lower critical points, similar to one found before [Macromolecules, 36,
5845 (2003)]. In the general case of systems whose interactions are not
attractive square wells, this mapping procedure can be a first approximation to
understand the phase diagram in the presence of solvent. We also present
simulation results for both the square well model and a modified Lennard-Jones
model.Comment: 18 pages, 9 figure
Capital allocation for credit portfolios with kernel estimators
Determining contributions by sub-portfolios or single exposures to
portfolio-wide economic capital for credit risk is an important risk
measurement task. Often economic capital is measured as Value-at-Risk (VaR) of
the portfolio loss distribution. For many of the credit portfolio risk models
used in practice, the VaR contributions then have to be estimated from Monte
Carlo samples. In the context of a partly continuous loss distribution (i.e.
continuous except for a positive point mass on zero), we investigate how to
combine kernel estimation methods with importance sampling to achieve more
efficient (i.e. less volatile) estimation of VaR contributions.Comment: 22 pages, 12 tables, 1 figure, some amendment
Integrating Social Justice Practices into Graduate Training: Collaborating with Stakeholders to Adapt Professional Development in Puerto Rico
Treating trauma has become an international social justice concern, with increasing numbers of graduate training programs prioritizing how to conceptualize needs and interventions within a trauma-informed framework. Minimal research and guidelines exist for adapting these trauma-informed practices for the local community context. Additionally, trauma-informed practices often fail to consider ongoing structural issues faced by oppressed communities such as poverty and racism. Social work, psychology, and counseling graduate training programs often rely on a cultural competency framework instead of a social justice framework that addresses racism and Whiteness. During our graduate Counseling and School Psychology training program at the University of Massachusetts Boston, we collaborated with stakeholders at a school and community center in San Juan, Puerto Rico to culturally adapt and deliver trainings in trauma-informed practices for staff using an ecological validity framework. Using our work in Puerto Rico as a case study, this paper addresses the cultural adaptation of trauma-informed practices and factors to consider when implementing trauma-informed practices, emphasizing the need for creating safety. Strategies for embedding this trauma-informed work into mental health graduate training programs and recommendations for working with individuals from marginalized groups in school settings are discussed
Can One Make Any Crash Prediction in Finance Using the Local Hurst Exponent Idea?
We apply the Hurst exponent idea for investigation of DJIA index time-series
data. The behavior of the local Hurst exponent prior to drastic changes in
financial series signal is analyzed. The optimal length of the time-window over
which this exponent can be calculated in order to make some meaningful
predictions is discussed. Our prediction hypothesis is verified with examples
of '29 and '87 crashes, as well as with more recent phenomena in stock market
from the period 1995-2003.Some interesting agreements are found.Comment: LaTeX 2e, 7 figures (included), 17 page
Extreme events in Italy from documentary sources: Venice as a case study
Venice risks to be submerged as a consequence of two problems: local land subsidence and sea level rise due to global warming. They both contribute to what is referred as Apparent Sea Level Rise (ASLR). Flooding Tides (locally:
Acqua Alta) submerge Venice with an exponentially increasing frequency. The Acqua Alta is generated by a number of factors, the main of them being the Sirocco
wind blowing over the Adriatic Sea, that ultimately displaces waters towards Venice. These extreme events have been investigated by using the documentary description of past floods, accurately reported over the last millennium, and tide gauge records for the recent period. A fundamental problem is to know the trend of the ASLR, possibly distinguishing between land subsidence and sea level components. Instrumental data go back to 1872 and a key point is to extend ourkno wledge back in time. Long-term ASLR has been investigated with the help of a biological indicator, i.e. the height of the green belt of the algae that live in the tidal range and whose upper front shows the average high tide level. Fortunately, in the first half
of the 18th century, this indicator was accurately drawn by the famous painter Antonio Canaletto (1697-1768) and his pupils, mainly Bernardo Bellotto (1722-1780), in their photographic paintings made with an optical camera obscura. It has been possible to compare the tidal level, as it was in the 1700s and today. After careful spot investigation and minor corrections for some changes to the hydrological system occurred in the meantime, the bulk submersion of Venice estimated from the paintings is 61 ± 11 cm with average yearly trend 1.9 mm y−1
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