Latest results on gamma-ray pulsars with Fermi

The Fermi Large Area Telescope (LAT) has been scanning the gamma-ray sky since 2008. The number of pulsars detected by the LAT now exceeds 200, making them by far the largest class of Galactic gamma-ray emitters. I discuss some of the latest pulsar discoveries made by the LAT, in particular those made since the release of the Pass 8 data.Comment: 5 pages, to appear in Il Nuovo Cimento

Fermi-LAT searches for gamma-ray pulsars

The Large Area Telescope (LAT) on the Fermi satellite is the first gamma-ray instrument to discover pulsars directly via their gamma-ray emission. Roughly one third of the 117 gamma-ray pulsars detected by the LAT in its first three years were discovered in blind searches of gamma-ray data and most of these are undetectable with current radio telescopes. I review some of the key LAT results and highlight the specific challenges faced in gamma-ray (compared to radio) searches, most of which stem from the long, sparse data sets and the broad, energy-dependent point-spread function (PSF) of the LAT. I discuss some ongoing LAT searches for gamma-ray millisecond pulsars (MSPs) and gamma-ray pulsars around the Galactic Center. Finally, I outline the prospects for future gamma-ray pulsar discoveries as the LAT enters its extended mission phase, including advantages of a possible modification of the LAT observing profile.Comment: Proceedings of the IAU Symposium 291, IAU XXVIII General Assembly, Beijing, China, August 2012: "Neutron Stars and Pulsars: Challenges and Opportunities after 80 years", Editor: Joeri van Leeuwen. To be published by Cambridge University Press. 6 page

The two tails of PSR J2055+2539 as seen by Chandra: analysis of the nebular morphology and pulsar proper motion

We analyzed two Chandra observations of PSR J2055+2539 (for a total integration time of $\sim$130 ks) in order to measure its proper motion and study its two elongated nebular features. We did not detect the proper motion, setting an upper limit of 240 mas yr$^{-1}$ (3$\sigma$ level), that translates into an upper limit on the transverse velocity of $\sim$700 km s$^{-1}$, for an assumed distance of 600 pc. A deep H$\alpha$ observation did not reveal the bow-shock associated with a classical pulsar wind nebula, thus precluding an indirect measurement of the proper motion direction. We determined the main axes of the two nebulae, which are separated by an angle of 160.8$^{\circ} \pm 0.7^{\circ}$, using a new approach based on the Rolling Hough Transformation (RHT). We analyzed the shape of the first 8' (out of the 12' seen by XMM-Newton) of the brighter, extremely collimated one. Based on a combination of our results from a standard analysis and a nebular modeling obtained from the RHT, we find that the brightest nebula is curved on an arcmin-scale, with a thickness ranging from $\sim9$" to $\sim31$" and a possible (single or multiple) helicoidal pattern. We could not constrain the shape of the fainter nebula. We discuss our results in the context of other known similar features, with particular emphasis on the Lighthouse nebula (associated with PSR J1101$-$6101). We speculate that a peculiar geometry of the powering pulsar may play an important role in the formation of such features.Comment: 12 pages, 9 figures, 1 table; accepted by Astronomy & Astrophysic

6U MeV CubeSat Mission: A low-cost approach towards gamma-ray astronomy

The low-energy gamma-ray (0.1-30 MeV) sky has been poorly observed since the decommissioning of the COMPTEL instrument on board the Compton Gamma-ray Observer (CGRO) satellite in 2000. The study of photons from this energy band (the MeV "gap") is, however, crucial to answer many unsolved questions in high-energy and multi-messenger astrophysics. Although several MeV gamma-ray missions have been proposed (e.g. AMEGO, e-ASTROGAM), these are mostly in the planning phase, and their launch is not expected until the next decade, at the earliest. Recently, there has been a proliferation of CubeSat missions proposed as "pathfinder" alternatives due to their low cost and faster cycles of implementation. Indeed, a MeV CubeSat for gamma-ray astronomy can be a suitable demonstrator for future, larger-scale MeV payloads. In this paper, a gamma-ray payload design with a silicon tracker and CsI calorimeter is proposed. We report the results of simulations to assess the performance of this payload possibility and compare these with other previous gamma-ray instruments.Comment: Submitted in Journal of Astronomical Telescopes, Instruments, and Systems(SPIE). Manuscript# 23097G. 31 pages and 7 figure

Unraveling the Nature of Unidentified High Galactic Latitude Fermi/LAT Gamma-ray Sources with Suzaku

We report on the results of deep X-ray follow-up observations of four unidentified Fermi/LAT gamma-ray sources at high Galactic latitudes using Suzaku. The studied objects were detected with high significance during the first 3 months of Fermi/LAT operation, and subsequently better localized in the Fermi/LAT 1 year catalog (1FGL). Possible associations with pulsars and active galaxies have subsequently been discussed, and our observations provide an important contribution to this debate. In particular, an X-ray point source was found within the 95% confidence error circle of 1FGL J1231.1-1410. X-ray spectrum is well-fitted by a blackbody with an additional power-law. This supports the recently claimed identification of this source with a millisecond pulsar (MSP) PSR J1231-1411. Concerning 1FGL J1311.7-3429, two X-ray sources were found within the LAT error circle. Even though the X-ray spectral and variability properties were accessed, their nature and relationship with the gamma-ray source remain uncertain. We found several weak X-ray sources in the field of 1FGL J1333.2+5056, one coinciding with CLASS J1333+5057. We argue the available data are consistent with the association between these two objects. Finally, we have detected an X-ray source in the vicinity of 1FGL J2017.3+0603. This object was recently suggested to be associated with a newly discovered MSP PSR J2017+0603, because of the spatial-coincidence and the gamma-ray pulse detection. We have only detected the X-ray counterpart of the CLASS J2017+0603, while we determined an X-ray flux upper limit at the pulsar position. All in all, our studies indicate while a significant fraction of unidentified high Galactic latitude gamma-ray sources is related to the pulsar and blazar phenomena, associations with other classes of astrophysical objects are still valid options.Comment: Accepted for publication in the Ap

Prospects for Pulsar Studies at MeV Energies

Enabled by the Fermi Large Area Telescope, we now know young and recycled pulsars fill the gamma-ray sky, and we are beginning to understand their emission mechanism and their distribution throughout the Galaxy. However, key questions remain: Is there a large population of pulsars near the Galactic center? Why do the most energetic pulsars shine so brightly in MeV gamma rays but not always at GeV energies? What is the source and nature of the pair plasma in pulsar magnetospheres, and what role does the polar cap accelerator play? Addressing these questions calls for a sensitive, wide-field MeV telescope, which can detect the population of MeV-peaked pulsars hinted at by Fermi and hard X-ray telescopes and characterize their spectral shape and polarization.Comment: 8 pages, 4 figures, Astro2020 Science White Paper submitted to the National Academies of Science

Systematic review on women's values and preferences concerning breast cancer screening and diagnostic services

Background: There is still lack of consensus on the benefit‐harm balance of breast cancer screening. In this scenario, women's values and preferences are crucial for developing health‐related recommendations. In the context of the European Commission Initiative on Breast Cancer, we conducted a systematic review to inform the European Breast Guidelines. Methods: We searched Medline and included primary studies assessing women's values and preferences regarding breast cancer screening and diagnosis decision making. We used a thematic approach to synthesise relevant data. The quality of evidence was determined with GRADE, including GRADE CERQual for qualitative research. Results: We included 22 individual studies. Women were willing to accept the psychological and physical burden of breast cancer screening and a significant risk of overdiagnosis and false‐positive mammography findings, in return for the benefit of earlier diagnosis. The anxiety engendered by the delay in getting results of diagnostic tests was highlighted as a significant burden, emphasising the need for rapid and efficient screening services, and clear and efficient communication. The confidence in the findings was low to moderate for screening and moderate for diagnosis, predominantly because of methodological limitations, lack of adequate understanding of the outcomes by participants, and indirectness. Conclusions: Women value more the possibility of an earlier diagnosis over the risks of a false‐positive result or overdiagnosis. Concerns remain that women may not understand the concept of overdiagnosis. Women highly value time efficient screening processes and rapid result delivery and will accept some discomfort for the peace of mind screening may provide

Characteristics and impact of interventions to support healthcare providers’ compliance with guideline recommendations for breast cancer: a systematic literature review

BackgroundBreast cancer clinical practice guidelines (CPGs) offer evidence-based recommendations to improve quality of healthcare for patients. Suboptimal compliance with breast cancer guideline recommendations remains frequent, and has been associated with a decreased survival. The aim of this systematic review was to characterize and determine the impact of available interventions to support healthcare providers' compliance with CPGs recommendations in breast cancer healthcare.MethodsWe searched for systematic reviews and primary studies in PubMed and Embase (from inception to May 2021). We included experimental and observational studies reporting on the use of interventions to support compliance with breast cancer CPGs. Eligibility assessment, data extraction and critical appraisal was conducted by one reviewer, and cross-checked by a second reviewer. Using the same approach, we synthesized the characteristics and the effects of the interventions by type of intervention (according to the EPOC taxonomy), and applied the GRADE framework to assess the certainty of evidence.ResultsWe identified 35 primary studies reporting on 24 different interventions. Most frequently described interventions consisted in computerized decision support systems (12 studies); educational interventions (seven), audit and feedback (two), and multifaceted interventions (nine). There is low quality evidence that educational interventions targeted to healthcare professionals may improve compliance with recommendations concerning breast cancer screening, diagnosis and treatment. There is moderate quality evidence that reminder systems for healthcare professionals improve compliance with recommendations concerning breast cancer screening. There is low quality evidence that multifaceted interventions may improve compliance with recommendations concerning breast cancer screening. The effectiveness of the remaining types of interventions identified have not been evaluated with appropriate study designs for such purpose. There is very limited data on the costs of implementing these interventions.ConclusionsDifferent types of interventions to support compliance with breast cancer CPGs recommendations are available, and most of them show positive effects. More robust trials are needed to strengthen the available evidence base concerning their efficacy. Gathering data on the costs of implementing the proposed interventions is needed to inform decisions about their widespread implementation