Enquête VISAT (travail posté et hypertension artérielle)

Objectif : Nous avons étudié le lien entre le travail posté et l'hypertension artérielle, dans une cohorte, en milieu professionnel, issue de l'enquête VISAT. Résultats : Dans notre étude, le travail posté n'apparaît pas être un facteur de risque d'HTA. Par contre, des liens significatifs ont été mis en évidence entre l'HTA et d'autres contraintes liées à l'organisation du temps de travail. Les sujets hypertendus étaient 2 fois plus à risque d'être obligés de se lever avant 5H. Les sujets obligés de ne pas dormir la nuit étaient plus à risque d'avoir des pressions artérielles plus élevées. Conclusion : Les contraintes organisationnelles concernant les horaires de travail semblent jouer un rôle sur des facteurs de risque cardiovasculaires établis.TOULOUSE3-BU Santé-Centrale (315552105) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Rectangular waveguide-to-CPW transition without air-bridge in the Ka-band

International audienceThe proposed waveguide-to-CPW transition is uniplanar, in line with the waveguide, and without air-bridge. Composed of a finline taper and a circular phase-shifter, it presents in simulation an insertion loss and a return loss better than 0.63 and 16.8 dB between 27 and 31 GHz. Measurements of the back-to-back structure are presented. (c) 2007 Wiley Periodicals, Inc

Characterisation and in vivo ecotoxicity evaluation of double-wall carbon nanotubes in larvae of the amphibian Xenopus laevis

International audienceBecause of their outstanding properties, carbon nanotubes (CNTs) are being assessed for inclusion in many manufactured products. Due to their massive production and growing number of potential applications, the impact of CNTs on the environment must be taken into consideration. The present investigation evaluates the ecotoxicological potential of double-walled carbon nanotubes (DWNTs) in the amphibian larvae Xenopus laevis at a large range of concentrations in water (from 10 to 500 mg L−1). Acute toxicity and genotoxicity were analysed after 12 days of static exposure in laboratory conditions. Acute toxicity was evaluated according to the mortality and the growth of larvae. The genotoxic effects were analysed by scoring the micronucleated erythrocytes of the circulating blood of larvae according to the International Standard micronucleus assay. Moreover, histological preparations of larval intestine were prepared after 12 days of exposure for observation using optical and transmission electron microscopy (TEM). Finally, the intestine of an exposed larva was prepared on a slide for analyse by Raman imaging. The results showed no genotoxicity in erythrocytes of larvae exposed to DWNTs in water, but acute toxicity at every concentration of DWNTs studied which was related to physical blockage of the gills and/or digestive tract. Indeed, black masses suggesting the presence of CNTs were observed inside the intestine using optical microscopy and TEM, and confirmed by Raman spectroscopy analysis. Assessing the risks of CNTs requires better understanding, especially including mechanistic and environmental investigations

Rapid viscoelastic changes are a hallmark of early leukocyte activation

International audienc

Author Correction: EMPReSS: standardized phenotype screens for functional annotation of the mouse genome

International audienceCorrection to: Nature Genetics, published online 1 November 2005.In the version of this article initially published, members of the Eumorphia Consortium appeared in the Supplementary Information but were not included in the main article. The full list of members appears below