Developing of the smart textile for energy expenditure monitoring

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Quantum stress tensor for massive vector field in the space-time of a cylindrical black hole

The components of the renormalized quantum Energy-Momentum tensor for a massive vector field coupled to the gravitational field configuration of a static Black-String are analytically evaluated using the Schwinger-DeWitt approximation. The general results are employed to investigate the pointwise energy conditions for the quantized matter field, and it is shown that they are violated at some regions of the spacetime, in particular the horizon of the black hole.Comment: 4 pages, 3 figure

Quantization of massive scalar fields over static black string backgrounds

The renormalized mean value of the corresponding components of the Energy-Momentum tensor for massive scalar fields coupled to an arbitrary gravitational field configuration having cylindrical symmetry are analytically evaluated using the Schwinger-DeWitt approximation, up to second order in the inverse mass value. The general results are employed to explicitly derive compact analytical expressions for the Energy-Momentum tensor in the particular background of the Black-String spacetime. In the case of the Black String considered in this work, we proof that a violation of the weak energy condition occur at the horizon of the space-time for values of the coupling constant, that include as particular cases the most interesting of minimal and conformal coupling.Comment: 4 page

Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders

Vogt-Koyanagi-Harada syndrome (VKH) and vitiligo are autoimmune diseases that target melanocytes. VKH affects several organs such as the skin, hair follicle, eyes, ears, and meninges, whereas vitiligo is often limited to the skin and mucosa. Many studies have identified immune genes, pathways and cells that drive the pathogeneses of VKH and vitiligo, including interleukins, chemokines, cytotoxic T-cells, and other leukocytes. Here, we present case studies of 2 canines with VKH and 1 with vitiligo, which occurred spontaneously in client-owned companion dogs. We performed comparative transcriptomics and immunohistochemistry studies on lesional skin biopsies from these cases in order to determine if the immunopathogenesis of autoimmune responses against melanocytes are conserved. In dogs, we found enrichment of T cell gene signatures, with upregulation of IFNG, TNF, PRF1, IL15, CTSW, CXCL10, and CCL5 in both VKH and vitiligo in dogs compared to healthy controls. Similar findings were reported in humans, suggesting that these genes play a role in the pathogenesis of spontaneous VKH and vitiligo. T cell-associated genes, including FOXP3 and TBX21, were enriched, while IGFBP5, FOXO1, and PECAM1 were decreased compared to healthy controls. Further, we identified TGFB3, SFRP2, and CXCL7 as additional potential drivers of autoimmune pigmentary disorders. Future studies exploring the immunopathogenesis of spontaneous autoimmunity will expand our understanding of these disorders, and will be useful in developing targeted therapies, repurposing drugs for veterinary and human medicine, and predicting disease prognosis and treatment response

Maintaining a Linked Data Cloud and Data Service for Second World War History

One of the great promises of Linked Data is to provide a shared data infrastructure into which new data can be imported and aligned with, forming a sustainable, ever growing Linked Data Cloud (LDC). This paper studies and evaluates this idea in the context of the WarSampo LDC that provides a data infrastructure for Second World War related ontologies and data in Finland, including several mutually linked graphs, totaling ca 12 million triples. Two data integration case studies are presented, where the original WarSampo LDC and the related semantic portal were first extended by a dataset of hundreds of war cemeteries and thousands of photographs of them, and then by another dataset of over 4450 Finnish prisoners of war. As a conclusion, lessons learned are explicated, based on hands-on experience in maintaining the WarSampo LDC in a production environment.Peer reviewe