2,909 research outputs found
Self-Forces on Electric and Magnetic Linear Sources in the Space-Time of a Cosmic String
In this paper we calculate the magnetic and electric self-forces, induced by
the conical structure of a cosmic string space-time, on a long straight wire
which presents either a constant current or a linear charge density. We also
show how these self-forces are related by a Lorentz tranformation and, in this
way, explain what two different inertial observers detect in their respective
frames.Comment: 10 pages, LaTeX, to be published in Phys. Rev. D
Expanded Vandermonde powers and sum rules for the two-dimensional one-component plasma
The two-dimensional one-component plasma (2dOCP) is a system of mobile
particles of the same charge on a surface with a neutralising background.
The Boltzmann factor of the 2dOCP at temperature can be expressed as a
Vandermonde determinant to the power . Recent advances in
the theory of symmetric and anti-symmetric Jack polymonials provide an
efficient way to expand this power of the Vandermonde in their monomial basis,
allowing the computation of several thermodynamic and structural properties of
the 2dOCP for values up to 14 and equal to 4, 6 and 8. In this
work, we explore two applications of this formalism to study the moments of the
pair correlation function of the 2dOCP on a sphere, and the distribution of
radial linear statistics of the 2dOCP in the plane
Spin Bottlenecks in the Quantum Hall Regim
We present a theory of time-dependent tunneling between a metal and a
partially spin-polarized two-dimensional electron system (2DES). We find that
the leakage current which flows to screen an electric field between the metal
and the 2DES is the sum of two exponential contributions whose relative weights
depend on spin-dependent tunneling conductances, on quantum corrections to the
electrostatic capacitance of the tunnel junction, and on the rate at which the
2DES spin-polarization approaches equilibrium. For high-mobility and
homogeneous 2DES's at Landau level filling factor , we predict a ratio
of the fast and slow leakage rates equal to where is the number
of reversed spins in the skyrmionic elementary charged excitations.Comment: 4 pages, 3 figures, submitted to Phys. Rev. Let
Effect of temperature anisotropy on various modes and instabilities for a magnetized non-relativistic bi-Maxwellian plasma
Using kinetic theory for homogeneous collisionless magnetized plasmas, we
present an extended review of the plasma waves and instabilities and discuss
the anisotropic response of generalized relativistic dielectric tensor and
Onsager symmetry properties for arbitrary distribution functions. In general,
we observe that for such plasmas only those electromagnetic modes whose
magnetic field perturbations are perpendicular to the ambient magneticeld,
i.e.,B1 \perp B0, are effected by the anisotropy. However, in oblique
propagation all modes do show such anisotropic effects. Considering the
non-relativistic bi-Maxwellian distribution and studying the relevant
components of the general dielectric tensor under appropriate conditions, we
derive the dispersion relations for various modes and instabilities. We show
that only the electromagnetic R- and L- waves, those derived from them and the
O-mode are affected by thermal anisotropies, since they satisfy the required
condition B1\perpB0. By contrast, the perpendicularly propagating X-mode and
the modes derived from it (the pure transverse X-mode and Bernstein mode) show
no such effect. In general, we note that the thermal anisotropy modifies the
parallel propagating modes via the parallel acoustic effect, while it modifies
the perpendicular propagating modes via the Larmor-radius effect. In oblique
propagation for kinetic Alfven waves, the thermal anisotropy affects the
kinetic regime more than it affects the inertial regime. The generalized fast
mode exhibits two distinct acoustic effects, one in the direction parallel to
the ambient magnetic field and the other in the direction perpendicular to it.
In the fast-mode instability, the magneto-sonic wave causes suppression of the
firehose instability. We discuss all these propagation characteristics and
present graphic illustrations
Explicit solution of the quantum three-body Calogero-Sutherland model
Quantum integrable systems generalizing Calogero-Sutherland systems were
introduced by Olshanetsky and Perelomov (1977). Recently, it was proved that
for systems with trigonometric potential, the series in the product of two wave
functions is a deformation of the Clebsch-Gordan series. This yields recursion
relations for the wave functions of those systems. In this note, this approach
is used to compute the explicit expressions for the three-body
Calogero-Sutherland wave functions, which are the Jack polynomials. We
conjecture that similar results are also valid for the more general
two-parameters deformation introduced by Macdonald.Comment: 10 page
Random Walks with Long-Range Self-Repulsion on Proper Time
We introduce a model of self-repelling random walks where the short-range
interaction between two elements of the chain decreases as a power of the
difference in proper time. Analytic results on the exponent are obtained.
They are in good agreement with Monte Carlo simulations in two dimensions. A
numerical study of the scaling functions and of the efficiency of the algorithm
is also presented.Comment: 25 pages latex, 4 postscript figures, uses epsf.sty (all included)
IFUP-Th 13/92 and SNS 14/9
On absolute moments of characteristic polynomials of a certain class of complex random matrices
Integer moments of the spectral determinant of complex
random matrices are obtained in terms of the characteristic polynomial of
the Hermitian matrix for the class of matrices where is a
given matrix and is random unitary. This work is motivated by studies of
complex eigenvalues of random matrices and potential applications of the
obtained results in this context are discussed.Comment: 41 page, typos correcte
ABCD of Beta Ensembles and Topological Strings
We study beta-ensembles with Bn, Cn, and Dn eigenvalue measure and their
relation with refined topological strings. Our results generalize the familiar
connections between local topological strings and matrix models leading to An
measure, and illustrate that all those classical eigenvalue ensembles, and
their topological string counterparts, are related one to another via various
deformations and specializations, quantum shifts and discrete quotients. We
review the solution of the Gaussian models via Macdonald identities, and
interpret them as conifold theories. The interpolation between the various
models is plainly apparent in this case. For general polynomial potential, we
calculate the partition function in the multi-cut phase in a perturbative
fashion, beyond tree-level in the large-N limit. The relation to refined
topological string orientifolds on the corresponding local geometry is
discussed along the way.Comment: 33 pages, 1 figur
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Ferroptosis is a form of regulated cell death that is caused by the iron-dependent peroxidation of lipids1,2. The glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4) prevents ferroptosis by converting lipid hydroperoxides into non-toxic lipid alcohols3,4. Ferroptosis has previously been implicated in the cell death that underlies several degenerative conditions2, and induction of ferroptosis by the inhibition of GPX4 has emerged as a therapeutic strategy to trigger cancer cell death5. However, sensitivity to GPX4 inhibitors varies greatly across cancer cell lines6, which suggests that additional factors govern resistance to ferroptosis. Here, using a synthetic lethal CRISPR-Cas9 screen, we identify ferroptosis suppressor protein 1 (FSP1) (previously known as apoptosis-inducing factor mitochondrial 2 (AIFM2)) as a potent ferroptosis-resistance factor. Our data indicate that myristoylation recruits FSP1 to the plasma membrane where it functions as an oxidoreductase that reduces coenzyme Q10 (CoQ) (also known as ubiquinone-10), which acts as a lipophilic radical-trapping antioxidant that halts the propagation of lipid peroxides. We further find that FSP1 expression positively correlates with ferroptosis resistance across hundreds of cancer cell lines, and that FSP1 mediates resistance to ferroptosis in lung cancer cells in culture and in mouse tumour xenografts. Thus, our data identify FSP1 as a key component of a non-mitochondrial CoQ antioxidant system that acts in parallel to the canonical glutathione-based GPX4 pathway. These findings define a ferroptosis suppression pathway and indicate that pharmacological inhibition of FSP1 may provide an effective strategy to sensitize cancer cells to ferroptosis-inducing chemotherapeutic agents
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