A Simulation Method Based on Material-Drying Oven Integration for Hot Air Drying of Lentinus edodes and Its Application

In this paper, a simulation method based on material-drying oven integration was developed for the hot air-drying process of Lentinus edodes. First of all, the drying characteristics were investigated under different drying conditions, and drying kinetic models were obtained at different air temperatures, relative humidities (RHs) and air flow rates. Then, drying kinetic derivative models to predict the drying process under different working conditions were obtained and used to calculate water evaporation rate, and the rate of water evaporation was introduced into the heat and mass transfer equations to develop mathematical models based on material-drying oven integration. Using the models, the pattern of temporal changes in air temperature, RH and air flow rate at any position inside the oven and moisture ratio (MR) was obtained. Finally, the drying characteristics were worked out using the integrated models. Overall, significant non-uniformity occurred during the drying process. As drying proceeded, non-uniformity decreased. In the direction of air flow, non-uniformity was more significant at positions closer to the oven’s top and bottom. In the transverse direction, non-uniformity was more significant at positions closer to the middle. In summary, the simulation method for hot air-drying of Lentinus edodes is meaningful for guiding the structural design of the drying chamber, the optimization of the drying process and the improvement of the product quality

A mining algorithm of user leader in social network

Mining user leader in social network is an important issue for user influence management.In this paper,a user leader mining algorithm in social network based on user influence assessments is proposed,which comprises aspects as follows:firstly,the model of proposed algorithm and its related definitions are described formally;secondly,a user leadership degree evaluation method is presented based on user influence and user activeness calculation;and finally,the user leader mining algorithm is proposed based on two factors of user leadership degree and user centrality.Furthermore,the experimental results show the feasibility and effectiveness of our proposed algorithm

Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke

Background Treatment of acute stroke, before a distinction can be made between ischemic and hemorrhagic types, is challenging. Whether very early blood-pressure control in the ambulance improves outcomes among patients with undifferentiated acute stroke is uncertain. Methods We randomly assigned patients with suspected acute stroke that caused a motor deficit and with elevated systolic blood pressure (≥150 mm Hg), who were assessed in the ambulance within 2 hours after the onset of symptoms, to receive immediate treatment to lower the systolic blood pressure (target range, 130 to 140 mm Hg) (intervention group) or usual blood-pressure management (usual-care group). The primary efficacy outcome was functional status as assessed by the score on the modified Rankin scale (range, 0 [no symptoms] to 6 [death]) at 90 days after randomization. The primary safety outcome was any serious adverse event. Results A total of 2404 patients (mean age, 70 years) in China underwent randomization and provided consent for the trial: 1205 in the intervention group and 1199 in the usual-care group. The median time between symptom onset and randomization was 61 minutes (interquartile range, 41 to 93), and the mean blood pressure at randomization was 178/98 mm Hg. Stroke was subsequently confirmed by imaging in 2240 patients, of whom 1041 (46.5%) had a hemorrhagic stroke. At the time of patients' arrival at the hospital, the mean systolic blood pressure in the intervention group was 159 mm Hg, as compared with 170 mm Hg in the usual-care group. Overall, there was no difference in functional outcome between the two groups (common odds ratio, 1.00; 95% confidence interval [CI], 0.87 to 1.15), and the incidence of serious adverse events was similar in the two groups. Prehospital reduction of blood pressure was associated with a decrease in the odds of a poor functional outcome among patients with hemorrhagic stroke (common odds ratio, 0.75; 95% CI, 0.60 to 0.92) but an increase among patients with cerebral ischemia (common odds ratio, 1.30; 95% CI, 1.06 to 1.60). Conclusions In this trial, prehospital blood-pressure reduction did not improve functional outcomes in a cohort of patients with undifferentiated acute stroke, of whom 46.5% subsequently received a diagnosis of hemorrhagic stroke. (Funded by the National Health and Medical Research Council of Australia and others

Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke

BackgroundTreatment of acute stroke, before a distinction can be made between ischemic and hemorrhagic types, is challenging. Whether very early blood-pressure control in the ambulance improves outcomes among patients with undifferentiated acute stroke is uncertain.MethodsWe randomly assigned patients with suspected acute stroke that caused a motor deficit and with elevated systolic blood pressure (≥150 mm Hg), who were assessed in the ambulance within 2 hours after the onset of symptoms, to receive immediate treatment to lower the systolic blood pressure (target range, 130 to 140 mm Hg) (intervention group) or usual blood-pressure management (usual-care group). The primary efficacy outcome was functional status as assessed by the score on the modified Rankin scale (range, 0 [no symptoms] to 6 [death]) at 90 days after randomization. The primary safety outcome was any serious adverse event.ResultsA total of 2404 patients (mean age, 70 years) in China underwent randomization and provided consent for the trial: 1205 in the intervention group and 1199 in the usual-care group. The median time between symptom onset and randomization was 61 minutes (interquartile range, 41 to 93), and the mean blood pressure at randomization was 178/98 mm Hg. Stroke was subsequently confirmed by imaging in 2240 patients, of whom 1041 (46.5%) had a hemorrhagic stroke. At the time of patients' arrival at the hospital, the mean systolic blood pressure in the intervention group was 158 mm Hg, as compared with 170 mm Hg in the usual-care group. Overall, there was no difference in functional outcome between the two groups (common odds ratio, 1.00; 95% confidence interval [CI], 0.87 to 1.15), and the incidence of serious adverse events was similar in the two groups. Prehospital reduction of blood pressure was associated with a decrease in the odds of a poor functional outcome among patients with hemorrhagic stroke (common odds ratio, 0.75; 95% CI, 0.60 to 0.92) but an increase among patients with cerebral ischemia (common odds ratio, 1.30; 95% CI, 1.06 to 1.60).ConclusionsIn this trial, prehospital blood-pressure reduction did not improve functional outcomes in a cohort of patients with undifferentiated acute stroke, of whom 46.5% subsequently received a diagnosis of hemorrhagic stroke. (Funded by the National Health and Medical Research Council of Australia and others; INTERACT4 ClinicalTrials.gov number, NCT03790800; Chinese Trial Registry number, ChiCTR1900020534.)