Experience of cardiac rehabilitation after coronary artery surgery: effects on health and risk factors

Objective:Cardiac rehabilitation (CR) programs are provided to support the recovery process following acute myocardial infarction and coronary artery bypass grafting (CABG). Attendance varies. We related attendance following CABG to severity of cardiac symptoms, general health status (Short Form-36) and prevalence of modifiable coronary artery disease (CAD) risk factors. METHODS: 209 patients due to undergo CABG were recruited and assessed preoperatively as well as at a mean of 16.4 months postoperatively. General health status was measured using the Short Form-36 questionnaire. Severity of cardiac symptoms was assessed on a visual analogue scale. Modifiable coronary artery disease risk factors (smoking, body mass index, hypertension and elevated cholesterol) and social deprivation index were noted

Postgerminative growth and lipid catabolism in oilseeds lacking the glyoxylate cycle

The glyoxylate cycle is regarded as essential for postgerminative growth and seedling establishment in oilseed plants. We have identified two allelic Arabidopsis mutants, icl-1 and icl-2, which lack the glyoxylate cycle because of the absence of the key enzyme isocitrate lyase. These mutants demonstrate that the glyoxylate cycle is not essential for germination. Furthermore, photosynthesis can compensate for the absence of the glyoxylate cycle during postgerminative growth, and only when light intensity or day length is decreased does seedling establishment become compromised. The provision of exogenous sugars can overcome this growth deficiency. The icl mutants also demonstrate that the glyoxylate cycle is important for seedling survival and recovery after prolonged dark conditions that approximate growth in nature. Surprisingly, despite their inability to catalyze the net conversion of acetate to carbohydrate, mutant seedlings are able to break down storage lipids. Results suggest that lipids can be used as a source of carbon for respiration in germinating oilseeds and that products of fatty acid catabolism can pass from the peroxisome to the mitochondrion independently of the glyoxylate cycle. However, an additional anaplerotic source of carbon is required for lipid breakdown and seedling establishment. This source can be provided by the glyoxylate cycle or, in its absence, by exogenous sucrose or photosynthesis

Post-settlement survival and growth of the Suminoe oyster, Crassostrea ariskensis, exposed to simulated emersion regimes

In high salinity habitats along the Middle and South Atlantic coasts of the United States the Eastern oyster, Crassostrea virginica occupies an intertidal refuge from predation, facilitated by its tolerance of aerial exposure and associated desiccation and temperature stress. Observations of the Suminoe oyster, C. ariakensis in its native environments in Asia reveal that this species is most commonly found subtidally or in the very low intertidal zone, suggesting that it may be less tolerant of aerial exposure. With serious consideration being given to introducing C. ariakensis to the mid-Atlantic region, it is important to understand the ability of this non-native species to invade and become established in the intertidal zone. We conducted experiments in an outdoor quarantined facility to compare the tolerances of C. virginica and C. ariakensis to varying levels of aerial exposure. Diploid C. virginica and C. ariakensis were set on 10 cm x 10 cm PVC tiles, held in a flow-though quarantine system exposed to ambient weather conditions, and subjected for eight weeks to four simulated tidal emersion regimes-(1) high intertidal (3.5 h emersion), (2) mid intertidal (2 h emersion), (3) low intertidal (1 h emersion), and (4) subtidal (constant immersion)-and four exposure orientations-(1,2) vertical north- and south-facing, and (3,4) horizontal up- and down-facing. Complete mortality of both species occurred in the high intertidal treatment by the end of week 1. No C. ariakensis had survived in the mid intertidal treatment by week 2 and very few remained alive in the low intertidal treatment. By the end of week 5, only 1.25% of the C. ariakensis had survived in the low intertidal treatment, whereas survival of C. ariakensis in the subtidal treatment was 36.88%. Significantly, C. virginica survival was 80.63% in the subtidal treatment and 67.50% and 28.13% on the vertically-oriented tiles (north- and south-facing treatments combined) in the low intertidal and mid intertidal treatments, respectively. Growth rates of C. virginica across tidal treatments were greatest in the subtidal treatment and C. ariakensis grew faster in the subtidal treatment than C. virginica. These results indicate that even with modest aerial exposure, under climatic conditions characteristic of summers in the mid-Atlantic region of the United States, C. ariakensis would suffer high rates of early post-settlement mortality, effectively restricting this non-native oyster species to subtidal environments if introduced to the region

Quantum dot emission from site-controlled ngan/gan micropyramid arrays

InxGa1−xN quantum dots have been fabricated by the selective growth of GaN micropyramid arrays topped with InGaN/GaN quantum wells. The spatially, spectrally, and time-resolved emission properties of these structures were measured using cathodoluminescence hyperspectral imaging and low-temperature microphotoluminescence spectroscopy. The presence of InGaN quantum dots was confirmed directly by the observation of sharp peaks in the emission spectrum at the pyramid apices. These luminescence peaks exhibit decay lifetimes of approximately 0.5 ns, with linewidths down to 650 me

Smart Focal Plane Technologies for VLT Instruments

As we move towards the era of ELTs, it is timely to think about the future role of the 8-m class telescopes. Under the OPTICON programme, novel technologies have been developed that are intended for use in multi-object and integral-field spectrographs. To date, these have been targeted at instrument concepts for the European ELT, but there are also significant possibilities for their inclusion in new VLT instruments, ensuring the continued success and productivity of these unique telescopes.Comment: 5 pages, to appear in the proceedings of the ESO Workshop "Science with the VLT in the ELT era

Developments in Practice V: IT Sourcing: Build, Buy, or Market

This paper describes the logical evolution of IT service provisioning through various delivery models over time concentrating on the rent era as well as the market era - an emerging external IT services marketplace that offers rich opportunities for IT organizations to become more cost-effective in the future. With the market era, IT organizations speculate that strategic business applications for mission-critical applications will remain in-house but delivery for standard and meta-industry applications, processes, and technology will be off-site. Thus, for most companies, it is likely that external IT providers will form part of their future service delivery package and that some IT departments will become both consumers and sellers of components. The implications of these developments for IT management are articulated and the elements of an IT sourcing strategy presented

Measurement of species flux from a bubble using an acousto-electrochemical technique

An acousto-electrochemical technique is presented which, for the first time, offers the potential for measuring the flux of dissolved species in a liquid resulting from bubbles of a specific chosen size in the population. Laboratory trials are presented, but the device itself was damaged in the surf zone and no data was obtained from the ocean deployment. Nevertheless, the preceding laboratory tests demonstrate the viability of the technique. The device responds to perturbations of the fluid around a small electrode. Three such sources of motion must be characterised if it is to achieve the objective stated above. First, the perturbations resulting form the translatory motions of bubbles in the liquid. To obtain bubble radius resolution in the measurement of mass flux, however, it is necessary to apply to driving (‘pump’) sound field. Bubbles close to resonance will, in addition to a translatory motion, impart to the liquid a component of mass flux at the pump frequency. This is detected. However to show that this is the result of bubble wall pulsation, and not someother coupling, the amplitude of the pump field is increased until the electrochemical sensor detects Faraday waves on the bubble wall. Not only does this prove the relation between mass flux to bubble wall motion, it provides a second route by which the radius-resolved component of mass flux might be identified. In these preliminary laboratory tests, electrochemical detection of these motions was achieved through the observation of current produced by the reduction of a suitable redox agent present within the liquid phase of the solution employed. Preparations were made to obtain preliminary data from the Hurst Spit 2000 surf zone trial, but the device was damaged by the environment

Summer and Autumn Movements and Habitat Use by Belugas in the Canadian High Arctic and Adjacent Areas

Twenty-one adult belugas (8M, 13F) were live-captured and instrumented with satellite-linked transmitters in the summer and fall of 1996. Twelve were captured in estuaries along the coast of Somerset Island in July and nine were captured in September in Croker Bay, SE Devon Island. This paper reports on the summer and autumn movements and dive depths of these animals from late July 1996 until the last tags ceased transmitting in November 1996. Of the 12 captured in July, 11 provided data for 30-126 days (mean = 84 days). Most of the animals moved rapidly to southern Peel Sound, where they all spent the month of August, making frequent deep dives, some of which were to depths near or at the seabed of the Franklin Trench. The belugas also used several bays along the coast of Prince of Wales Island and another one on Melville Peninsula. They left southern Peel Sound between late August and early September and moved rapidly to the south coast of Devon Island, many using Maxwell Bay and Croker Bay for several days. All belugas instrumented in Croker Bay in September, as well as the summer-tagged individuals that were still transmitting, moved east and north along the south and east coasts of Devon Island, eventually reaching Jones Sound and north Baffin Bay. They used many bays along the east coast of Devon Island and dove to depths often exceeding 200 m in the surrounding waters. Fifteen of the tags continued to transmit during the period when belugas are normally observed migrating along the West Greenland coast (late September-early October). Only one of the tagged animals moved to Greenland waters in late September. The others remained in the area known in winter as the North Water. The autumn tracking results suggest that the North Water may harbour a larger winter population of belugas than was previously suspected.Durant l'été et l'automne de 1996, on a capturé 21 bélugas adultes (8 mâles, 13 femelles), qu'on a équipés d'émetteurs-satellite. Douze d'entre eux ont été capturés en juillet dans des estuaires de l'île Somerset et neuf autres l'ont été en septembre dans la baie Croker du sud-est de l'île Devon. Cet article fait état des déplacements et profondeurs de plongée de ces animaux en été et en automne, de la fin juillet 1996 jusqu'à ce que les émetteurs cessent de transmettre, en novembre 1996. Sur 12 individus capturés en juillet, 11 ont transmis des données pendant 30 à 126 jours (moy. = 84 jours). La plupart des animaux se sont déplacés rapidement vers le sud du détroit de Peel où ils ont tous passé le mois d'août, plongeant fréquemment à de grandes profondeurs dont certaines atteignaient ou presque le fond marin de la fosse Franklin. Les bélugas ont aussi utilisé plusieurs baies le long de la côte de l'île Prince of Wales et une autre dans la péninsule Melville. Ils ont quitté le sud du détroit de Peel entre fin août et début septembre et se sont déplacés rapidement vers la côte sud de l'île Devon. Plusieurs d'entre eux ont passé quelques jours dans les baies Maxwell et Croker. Tous les bélugas équipés d'instruments dans la baie Croker en septembre, ainsi que ceux relâchés en été et qui continuaient à transmettre, se sont déplacés vers l'est et le nord en suivant les côtes sud et est de l'île Devon, finissant par atteindre le détroit de Jones et le nord de la baie de Baffin. Ils ont occupé de nombreuses baies sur la côte est de l'île Devon et effectué des plongées atteignant souvent plus de 200 m dans les eaux avoisinantes. Quinze des émetteurs ont continué à transmettre durant la période où on observe normalement des bélugas en migration au large de la côte du Groenland occidental (fin septembre - début octobre). Un seul des animaux portant un émetteur a pénétré dans les eaux groenlandaises à la fin septembre. Les autres sont restés dans une zone connue en hiver sous le nom de "North Water" (Eau du Nord). Ces résultats suggèrent qu'en hiver le "North Water" abrite une population de bélugas plus abondante qu'on ne le pensait antérieurement

Hematology and Plasma Chemistry as Indicators of Health and Ecological Status In Beluga Whales, Delphinapterus Leucas

The capture of beluga whales, Delphinapterus leucas, for instrumentation or tagging afforded the opportunity to collect blood, which was analyzed to evaluate the animals' health and gain information on basic physiological systems. Here, we report on hematological and plasma chemical constituents in samples obtained from 183 belugas, 55 of which were handled during attempts to apply tracking instruments. The other 128 samples were either drawn from live belugas captured for exhibit in zoological parks or research or obtained from the fresh carcasses of whales taken by Inuit hunters. The data span a 15-year period beginning in 1983 and represent various beluga stocks in the Canadian Arctic. The majority of the specimens were collected during the summer or estuarine phase of the belugas' annual cycle. Comparisons by age group, sex, stock, season, and year revealed significant differences in most of the cellular and chemical constituents examined. These results demonstrate some of the variability that might be encountered when examining a "random" selection of belugas at a particular location and time. Immature-sized whales had higher leucocyte counts, electrolyte concentrations, enzyme activity, total protein, albumin, hemoglobin, and some metabolites than older animals. Sex alone was associated with few hematological and plasma chemical differences. Seasonal variation in thyroid hormone activity was linked to marked environmental changes associated with the transition from cold oceanic waters to relatively warm estuaries. Two belugas recaptured 19 and 24 days after instrumentation showed changes in leucocyte counts, hematocrit, and a variety of plasma chemical constituents, some of which indicate inflammation and a likely physiological response to handling and tagging stresses.On a profité du fait qu'on capturait des bélougas, Delphinapterus leucas, en vue de les équiper d'instruments ou de les marquer, pour prélever des échantillons de sang qu'on a ensuite analysés afin d'évaluer l'état de santé des individus et de collecter de l'information sur leurs grands systèmes physiologiques. Nous présentons ici un rapport sur les constituants hématologiques et chimiques du plasma dans des échantillons provenant de 183 bélougas, dont 55 ont été manipulés au cours de tentatives visant à les équiper d'instruments de poursuite. Les 128 autres échantillons ont été obtenus soit de bélougas vivants capturés en vue d'être placés dans des zoos ou pour la recherche, soit de carcasses fraîches de baleines prises par les chasseurs inuits. Les données couvrent une période de 15 ans, commençant en 1983, et représentent divers stocks de bélougas de l'océan Arctique canadien. La plupart des spécimens ont été recueillis durant l'été ou durant la phase estuarienne du cycle annuel du bélouga. Des comparaisons par groupe d'âge, sexe, stock, saison et année ont révélé des différences marquées dans la plupart des constituants cellulaires et chimiques examinés. Ces résultats font ressortir une certaine variabilité à laquelle on peut s'attendre quand on étudie un échantillon "aléatoire" de bélougas pris à un endroit et à un moment donnés. Par rapport à des individus plus âgés, les baleines qui n'avaient pas atteint leur taille adulte avaient un compte de globules blancs plus élevé, de même qu'une plus forte concentration d'électrolytes, une plus grande activité enzymatique, et un taux plus fort d'albumine, d'hémoglobine et de certains métabolites. Le sexe seul n'était associé qu'à quelques différences hématologiques et chimiques du plasma. Une variation saisonnière de l'activité des hormones thyroïdiennes était liée à des changements nets du milieu correspondant à la transition des eaux froides océaniques aux estuaires relativement chauds. Deux bélougas recapturés 19 et 24 jours après avoir été équipés d'instruments montraient des changements dans le compte de globules blancs, dans l'hématocrite et dans divers constituants chimiques du plasma, dont certains révèlent une inflammation et probablement une réaction physiologique au stress dû à la manipulation et au marquage

Remembrance of Odors Past Human Olfactory Cortex in Cross-Modal Recognition Memory

AbstractEpisodic memory is often imbued with multisensory richness, such that the recall of an event can be endowed with the sights, sounds, and smells of its prior occurrence. While hippocampus and related medial temporal structures are implicated in episodic memory retrieval, the participation of sensory-specific cortex in representing the qualities of an episode is less well established. We combined functional magnetic resonance imaging (fMRI) with a cross-modal paradigm, where objects were presented with odors during memory encoding. We then examined the effect of odor context on neural responses at retrieval when these same objects were presented alone. Primary olfactory (piriform) cortex, as well as anterior hippocampus, was activated during the successful retrieval of old (compared to new) objects. Our findings indicate that sensory features of the original engram are preserved in unimodal olfactory cortex. We suggest that reactivation of memory traces distributed across modality-specific brain areas underpins the sensory qualities of episodic memories